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Optical coherence tomography method and system with transverse ultra-high resolution

An optical coherence tomography and transverse technology, which is applied in the field of transverse ultra-high resolution optical coherence tomography methods and systems, can solve the problems of limited ability to improve the transverse spatial resolution, and achieve ultra-high transverse spatial resolution and large application range effect

Active Publication Date: 2019-01-18
江苏度微光学科技有限公司
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Problems solved by technology

However, these methods are still limited by the diffraction limit of the optical system, and the ability to improve the lateral spatial resolution is limited.

Method used

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  • Optical coherence tomography method and system with transverse ultra-high resolution
  • Optical coherence tomography method and system with transverse ultra-high resolution
  • Optical coherence tomography method and system with transverse ultra-high resolution

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Embodiment

[0021] figure 1 Shown is a schematic diagram of an ultra-high lateral resolution optical coherence tomography system: the system includes 1 broadband light source, 2 fiber isolators, 3 fiber couplers, 4 fiber polarization controllers, 5 reference arms, 6 sample arms, and 7 detection arms and 8 computers. The 2 optical fiber isolators prevent the reverse transmission optical signal from entering the 1 broadband light source; the 4 optical fiber polarization controllers adjust the polarization direction of the reference light to control the contrast of the coherent signal between the reference light and the sample light; It is composed of a straight lens and a plane mirror installed on an electronically controlled translation stage; the 6 sample arms include 9 light field switching modules, 10 scanning modules and 11 imaging lenses, and different illumination light field modes are automatically adjusted through the light field switching module, The scanning module realizes one-...

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Abstract

The invention discloses an optical coherence tomography method and a system with transverse ultra-high resolution. The method comprises: controlling illumination field of a sample arm by switching light fields; acquiring two-dimensional or three-dimensional scanning sample information in multiple sets of different illumination modes; performing digital coherence synthesis of an ultra-high resolution point spread function according to a point spread function corresponding to different illumination modes; weighted stacking sample information in all illumination modes to obtain an intermediate processed image; using the ultra-high resolution point spread function to deconvolve the intermediate processing image; and reconstructing an optical coherence tomography image with the transverse ultra-high resolution. Compared with existing optical coherence tomography, the method and the system modulates the illumination field by physically constructing different illumination modes, performs thedigital coherence synthesis of the ultra-high resolution point spread function, and reconstructs an ultra-high transverse spatial resolution image according to deconvolution algorithm, thereby expanding application range of the optical coherence tomography and the system.

Description

technical field [0001] The present invention relates to an optical coherence tomography technology, in particular to a transverse ultra-high resolution optical coherence tomography method and system. Background technique [0002] Optical coherence tomography (OCT) is an emerging optical imaging technology that can perform non-contact, non-invasive, rapid, high-resolution imaging, and is mainly used in the clinical diagnosis of ophthalmology, cardiovascular and other diseases , archaeology, non-destructive testing of integrated circuits, glass panels and photovoltaic modules, etc. [0003] As one of the most important technical indicators of optical imaging technology, spatial resolution has always been constrained by the diffraction limit of the optical imaging system. How to break through this limit to obtain higher resolution is the driving force to promote the continuous development of various optical imaging technologies including OCT technology. In the OCT system, the...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01B9/02G01N21/47
CPCG01B9/02091G01N21/47
Inventor 马庆匡翠方罗向东杨春雷
Owner 江苏度微光学科技有限公司
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