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Liquid dietary supplement formulation compositions

A composition, the technology of an aqueous composition, applied in the field of preparation ingredients for oral administration, liquid dietary supplement preparation composition

Inactive Publication Date: 2019-02-22
曼普雷特·S·沃德瓦
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the concentrations of calcium and magnesium minerals in these dosage forms are relatively low compared to those in suspension products, thus requiring relatively large doses to meet the recommended daily allowance

Method used

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  • Liquid dietary supplement formulation compositions
  • Liquid dietary supplement formulation compositions
  • Liquid dietary supplement formulation compositions

Examples

Experimental program
Comparison scheme
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preparation example Construction

[0150] The method of the present invention includes a preparation method or a production method. Various manufacturing techniques can be used to prepare the compositions described herein. Preferably, the composition is prepared by one or more simple manufacturing processes comprising dissolving or mixing the ingredients in water. However, other production processes may also be used. Non-limiting examples of commonly used production processes may include: mixing the ingredients in an aqueous solution, mixing one or more aqueous solutions; removing water from the diluted composition by evaporation, dialysis, ultrafiltration, or freeze-drying to obtaining desired concentrations of calcium and magnesium compounds and optional ingredients; and by using combinations of these production processes to obtain desired concentrations of calcium and magnesium compounds and optional ingredients. Also, where optional ingredients are poorly soluble, solubilization, suspension and / or emulsif...

Embodiment approach

[0153] Based on the foregoing description, other non-limiting embodiments of the present invention are described as follows:

[0154] 31x. A method of fortifying a beverage or food with calcium and magnesium, the method comprising:

[0155] Add at least about 1 μl to about 60 ml of the composition of embodiment 1x to about a cup of drink or about 1 serving of food, or, correspondingly, a larger or smaller amount of the composition to a larger or In smaller amounts of drink or food.

[0156] 32x. A method of fortifying a beverage or food with calcium and magnesium, the method comprising:

[0157] Add at least one drop or about 50 μl to about 30 ml of the composition described in embodiment 1x to a glass of drink or a serving of food, or, correspondingly, add a larger or smaller amount of the composition to a larger or more In small amounts of drink or food.

[0158] 33x. A method of fortifying a beverage or food with calcium, magnesium, and other optional ingredients, the me...

Embodiment 1

[0174] Twenty-five formulations were prepared with varying concentrations of calcium chloride and magnesium chloride dissolved in distilled water. As shown in Table 1, the formulations contained different ratios of elemental calcium and elemental magnesium in the formulation. For each of these ratios, formulations were prepared at total concentrations (total concentrations of calcium compound and magnesium compound) of 1M, 1.5M, 2.0M, 2.5M and 3.0M. All formulations were visually clear, indicating complete dissolution of the calcium and magnesium compounds. A bacterial suspension of Escherichia coli (E. coli) was spiked into aliquots of each of the twenty-five formulations and mixed. A positive control was prepared by spiking and mixing the same E. coli suspension in distilled water. Spiked samples were incubated at room temperature for one day, and then dilutions were plated on Petrifilm plates (designed for total aerobic counts) to assess microbial growth or inhibition. T...

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PUM

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Abstract

This invention relates to liquid dietary supplement formulation compositions that provide dietary minerals and additional optional ingredients beneficial for health; methods of design and manufactureof such compositions; and methods to enable convenient oral ingestion of the formulation ingredients, by adding the formulations to drinking water, beverages, foods, or meals. The formulation compositions of this invention generally include water, water-soluble calcium compound(s), water-soluble magnesium compound(s), and additional optional ingredients, wherein the sum of the concentrations of the calcium and magnesium compounds is most preferably 2 molar or more, up to the point of saturation. The formulations of this invention possess inherent resistance to microbial growth. The formulations of this invention and variations thereof can be used as dietary supplements to increase intake of beneficial minerals, to mineralize water, to fortify foods or beverages, and can also be used to prepare a variety of additional liquid formulations by varying the calcium and magnesium compounds, and / or by adding one or more compatible ingredient(s).

Description

[0001] This application is a divisional application of the Chinese invention patent application with the application number 201280069471.7, the application date is December 12, 2012, and the invention name is "Liquid Dietary Supplement Preparation Composition". [0002] Cross References to Related Applications [0003] This application claims priority to US Provisional Application No. 61 / 569,790, filed December 13, 2011, and US Non-Provisional Application No. 13 / 712,328, filed December 12, 2012. technical field [0004] The present invention relates generally to dietary supplements, and, more particularly, the present invention relates to liquid dietary supplement formulation compositions, which generally include water-soluble dietary minerals and other optional health-benefiting ingredients; the present invention It relates to methods for designing and producing such formulation compositions and methods for facilitating oral administration of the formulation components by ad...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/00A23L33/16
CPCC02F1/68A23L2/52A23L33/16A61K33/06A61K33/14A61K2300/00
Inventor 曼普雷特·S·沃德瓦
Owner 曼普雷特·S·沃德瓦