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Preparation method of rose sleep helping capsules

The technology of rose flower and rose flower extract is applied in the field of preparation of rose flower sleep aid capsules, which can solve problems such as increased burden on the liver and kidney, and achieve the effects of promoting sleep quality, being easy to take, and having stable properties.

Pending Publication Date: 2019-03-15
方林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Some existing drugs for treating insomnia are mainly chemical synthetic drugs, long-term use will increase the burden on the liver and kidneys, and have side effects

Method used

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  • Preparation method of rose sleep helping capsules
  • Preparation method of rose sleep helping capsules
  • Preparation method of rose sleep helping capsules

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Step 1, preparation of rose rough extract: mix rose and water in a weight ratio of 1:6, extract at 70°C for 1 hour, filter the extract through filter cloth, concentrate under reduced pressure until the volume is reduced by 40%, and obtain Rose crude extract;

[0027] Step 2, refinement of rose extract: adding adsorbent to the crude rose extract for adsorption treatment, the adsorption time is 0.5h, the adsorption temperature is 25°C, and the adsorbent used is cellulose acetate modified chitosan microspheres , the adsorbent is filtered out to obtain rose extract; the preparation method of the cellulose acetate modified chitosan microspheres is: step a, the preparation contains 2wt% chitosan, 0.5wt% PEG 4000, 1wt% For the aqueous solution of citric acid, mix the aqueous solution with liquid paraffin at a volume ratio of 1:0.5, add dispersant Tween 80 0.01 times the weight of chitosan, stir evenly, heat up to 40°C, and then add 15wt% of Formaldehyde solution, the molar ra...

Embodiment 2

[0034] Step 1, preparation of rose rough extract: mix rose and water in a weight ratio of 1:8, extract at 80°C for 3 hours, filter the extract through a filter cloth, concentrate under reduced pressure until the volume is reduced by 50%, and obtain Rose crude extract;

[0035]Step 2, the refinement of rose extract: add adsorbent to the crude extract of rose for adsorption treatment, the adsorption time is 2h, the adsorption temperature is 35°C, the adsorbent used is cellulose acetate modified chitosan microspheres, The adsorbent is filtered out to obtain rose flower extract; the preparation method of the cellulose acetate modified chitosan microspheres is: step a, the preparation contains 4wt% chitosan, 1 wt% PEG 4000, 1.5wt% For the aqueous solution of citric acid, mix the aqueous solution and liquid paraffin according to the volume ratio of 1:0.8, add dispersant Tween 80 which is 0.03 times the weight of chitosan, stir evenly, heat up to 45°C, and then add 20wt% of Formalde...

Embodiment 3

[0042] Step 1, preparation of crude rose extract: mix rose and water in a weight ratio of 1:7, extract at 75°C for 2 hours, filter the extract through a filter cloth, concentrate under reduced pressure until the volume is reduced by 45%, and obtain Rose crude extract;

[0043] Step 2, the refinement of rose extract: add adsorbent to the crude extract of rose for adsorption treatment, the adsorption time is 1h, the adsorption temperature is 30°C, the adsorbent used is cellulose acetate modified chitosan microspheres, The adsorbent is filtered out to obtain rose flower extract; the preparation method of the cellulose acetate modified chitosan microspheres is: step a, preparing 3wt% chitosan, 0.8wt% PEG 4000, 1.2wt% For the aqueous solution of citric acid, mix the aqueous solution and liquid paraffin at a volume ratio of 1:0.6, add Tween 80, a dispersant 0.02 times the weight of chitosan, stir evenly, heat up to 42°C, and then add dropwise 15-20wt % formaldehyde solution, the mo...

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Abstract

The invention relates to a preparation method of rose sleep helping capsules and belongs to the technical field of health-care products. The preparation method comprises the following steps: extracting roses and spina date seeds to obtain extract capable of promoting sleep quality; and purifying and decontaminating the extract to prepare the soft capsules. The extraction method provided by the invention can remove impurities affecting the storage stability of the soft capsules in the extract effectively, and the obtained soft capsules have the characteristic of being easy to take and stable inproperty.

Description

technical field [0001] The invention relates to a method for preparing a rose flower sleep aid capsule, which belongs to the technical field of health care products. Background technique [0002] Many people in life are easily troubled by the problem of insomnia. If the problem of insomnia is left alone, it may cause harm to our life. Nowadays, many people think that insomnia is a minor disease, and they don’t need to see a doctor, take medicine and injections, but they don’t know that insomnia complications will bring great difficulty to the treatment. Long-term insomnia will lead to serious mental complications such as anxiety, depression, and mania as the disease progresses. Patients of this type are unwilling to take the initiative to contact new things and new environments, and it is extremely difficult to cooperate with doctors' treatment. Once the recovery period is stimulated, the recurrence of the disease will also increase. Long-term insomnia will cause intelle...

Claims

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Application Information

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IPC IPC(8): A61K36/738A61K9/48A61P25/20
CPCA61K9/4866A61K36/725A61K36/738A61K2236/331A61K2236/51A61P25/20A61K2300/00
Inventor 方林
Owner 方林
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