8 results about "Soft Capsule Dosage Form" patented technology

The invention discloses an enteric-coated Shuanghuanglian soft capsule and a preparation method thereof. The enteric-coated Shuanghuanglian soft capsule comprises traditional Chinese medicine fructus forsythiae, honeysuckle, a scutellaria baicalensis extract and an enteric-coated soft capsule shell material, the preparation method comprises the following steps: performing enzyme deactivation by boiling water, performing wet crushing, performing solid-liquid separation, concentrating filtrate, performing alcohol precipitation, and performing vacuum drying to extract the components of fructus forsythiae, honeysuckle and scutellaria baicalensis. The enteric-coated Shuanghuanglian soft capsule dosage form belongs to a completely sealed capsule shell, so that the loss of volatile components is avoided. The enteric-coated soft capsule is insoluble in a gastric solution, and can be dissolved and released when reaching an intestinal environment, so that the damage of gastric acid to medicinal components is avoided, and the characteristic that medicinal components of honeysuckle and fructus forsythiae are absorbed in a small intestine section in literature records is met. Wet grinding extraction is adopted to replace decoction extraction, heat-sensitive active ingredients in the prescription are prevented from being damaged by heat, volatile oil is synchronously collected in the concentration process, the defect that volatile oil contained in fructus forsythiae and honeysuckle in the prior art cannot be collected is overcome, and the effective components of the prescription are prepared in the medicament more completely. In the preparation process, hydrochloric acid is not added for adjusting the pH during scutellaria baicalensis extraction, so that side effects caused by introduction of Cl <-> into the medicament are avoided, and the medicament safety is improved.

The invention belongs to the technical field of health care products or medicines, and discloses a high-purity alkaline compound vitamin C composition, and a liposome soft capsule and a preparation method thereof. The invention firstly provides a composition composed of sodium ascorbate, sodium erythorbate and the like, and the sodium erythorbate and trisodium citrate are utilized to synergistically construct a chemical dual-stability barrier. On the basis, the composition is further encapsulated through a low-temperature oxygen-free liposome preparation process to form a physical protection barrier capable of improving bioavailability, and the composition is prepared into a soft capsule dosage form. According to the preparation method disclosed by the invention, low-temperature and inert gas protection measures run through all the time, and the preparation method not only comprises superfine grinding and mixing of the core composition, but also comprises low-temperature and high-pressure homogenization and subsequent filling processes of the lipidosome. The final product is alkalescent and good in stability, and the absorption rate of active ingredients is remarkably improved through a liposome delivery system.

The invention belongs to the technical field of medicines, and particularly relates to an icaritin tablet and a preparation method thereof. According to the tablet prescription, the problem of in-vitro dissolution of an indissolvable drug icaritin is solved, and compared with commercially available icaritin soft capsules, the tablet has greater advantages in manufacturing cost and production efficiency compared with a soft capsule dosage form. The tablet process is easy to implement and suitable for industrial production.

The present application relates to the technical field of biological medicine, in particular to a capsule with the function of relieving physical fatigue, a preparation method and application thereof, the composition contains coenzyme Q10 and mangosteen shell extract as core active ingredients in a specific mass ratio, and preferably, sea buckthorn seed extract is added. The present application further provides two optimized extraction processes of the mangosteen shell extract and the sea buckthorn seed extract. In addition, the composition is further mixed with oily bases, suspending agents, emulsifying agents and other excipients to form a soft capsule dosage form. Through the synergistic effect of various active ingredients, the product can effectively improve the body's endurance, accelerate the removal of metabolic products and enhance the antioxidant capacity, thereby significantly relieving physical fatigue. The product has the characteristics of naturalness, safety, high efficiency, high bioavailability and the like, and can be used for preparing food, health food or medicine for relieving physical fatigue.

The present invention relates to the use of a pharmaceutical carrier in the preparation of an antidiabetic pharmaceutical composition. In particular, the present invention relates to the use of a pharmaceutical carrier in the preparation of an antidiabetic pharmaceutical composition, wherein the pharmaceutical carrier consists of well-mixed sesame oil and beeswax, and the antidiabetic pharmaceutical composition consists of oryzanol and berberine hydrochloride as active ingredients, wherein oryzanol is present in an amount of 1-5% by weight, berberine hydrochloride is present in an amount of 5-50% by weight, beeswax is present in an amount of 1-20% by weight, and sesame oil is present in an amount of 40-85% by weight, based on the total weight of the pharmaceutical composition.The present invention further relates to an antidiabetic pharmaceutical composition as above, which is subjected to compression, washing, drying and screening, and filling into a vial to obtain a soft capsule dosage form product. The product has advantages such as stable control of blood glucose, lowering of blood glucose level and blood lipids, protection of liver function, and reduction of gastrointestinal irritation.

Disclosed are methods of using a naproxen fill formulation suitable for encapsulation into a soft gel dosage unit to treat inflammation and pain. Methods include administering naproxen to a subject in need thereof to treat pain and inflammation. Methods can include administering naproxen together with another medicament to a subject in need thereof to treat an additional condition such as a cough, cold, allergy, congestion, etc.

The invention relates to the technical field of biological medicine, in particular to a capsule with a function of relieving physical fatigue and a preparation method and application thereof, the composition comprises coenzyme Q10 and mangosteen shell extract as core active ingredients according to a specific mass ratio, and sea buckthorn seed extract can be preferably added. The invention also provides two optimized extraction processes of the mangosteen shell extract and the sea buckthorn seed extract, in addition, the composition is further scientifically matched with auxiliary materials such as an oily matrix, a suspending aid and an emulsifier to prepare a soft capsule dosage form, and the product has a synergistic effect through a plurality of active ingredients, so that the effect of improving the bioavailability of the product is achieved. The composition can effectively improve body endurance, accelerate metabolite removal and enhance oxidation resistance so as to significantly relieve physical fatigue, has the characteristics of naturalness, safety, high efficiency, high bioavailability and the like, and can be used for preparing food, health food or medicine for relieving physical fatigue.