Dedicated dispersion liquid for preparing high-resolution chromosome for karyotyping analysis
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- BEIJING INST OF HUMAN GENETICS & REPRODUCTION MEDICINE LTD CHINA
- Publication Date
- 2019-03-29
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Abstract
Description
technical field
[0001] The invention belongs to the field of biotechnology and relates to the special preparation of high-resolution chromosome dispersion liquid for karyotype analysis. Background technique
[0002] Chromosomes are the carriers of genes. There are 23 pairs of 46 chromosomes in normal human cells, of which 22 pairs and 44 are autosomes, and the other pair is 2 sex chromosomes. Chromosomes may undergo quantitative and structural changes, resulting in various genetic defects, congenital genetic diseases, embryo suspension and spontaneous abortion, tumors, etc. Diseases caused by chromosomal abnormalities are generally called chromosomal diseases.
[0003] Chromosomal detection is currently mostly used in clinical practice such as reproduction, obstetrics and gynecology, newborns, blood diseases, tumors and other specialties. Although the method is relatively simple, it is still the gold standard for prenatal diagnosis by using the chromosome banding technique...