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Tyrosinase inhibitor, whitening and skin refining lotion and preparation method thereof

A technology of tyrosinase and whitening skin water, which is applied in skin care preparations, pharmaceutical formulas, cosmetic preparations, etc., can solve the problems of poor tyrosinase inhibition, and achieve excellent inhibition, inhibitory activity, Raw materials are easy to effect

Inactive Publication Date: 2019-04-05
GUANGZHOU KENENG COSMETICS RES CO LTD +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In view of the poor effect of the Chinese herbal medicine whitening and freckle-removing preparations in the prior art, and the problems such as poor tyrosinase inhibitory effect, the present invention firstly provides a tyrosinase inhibitor

Method used

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  • Tyrosinase inhibitor, whitening and skin refining lotion and preparation method thereof
  • Tyrosinase inhibitor, whitening and skin refining lotion and preparation method thereof
  • Tyrosinase inhibitor, whitening and skin refining lotion and preparation method thereof

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no. 1 approach

[0032] The first embodiment of the present invention provides a tyrosinase inhibitor, comprising: kudzu root extract and saffron extract. The tyrosinase inhibitor of the invention can well inhibit the activity of tyrosinase, and has excellent whitening effect when used in cosmetics, especially when used in whitening and fine skin water.

[0033] Pueraria lobata (wild) Ohwi is the dry root of Pueraria lobata (wild) Ohwi or Puerariathomsonil Benth, which is also known as Pueraria lobata (wild) Ohwi. There are 11 species of Pueraria in my country, and except for Pueraria kudzu which is mainly cultivated artificially, the rest are mainly wild. The Chinese Pharmacopoeia (1990 edition) recorded two original plants of the genus Pueraria mirifica and Pueraria pueraria.

[0034] The main components of kudzu root are: starch, cellulose, protein and total flavonoids, and also contain a small amount of fat, pectin, tannins and alkaloids. There are 11 kinds of amino acids and 11 kinds of...

no. 2 approach

[0041] The second embodiment of the present invention provides a whitening skin toner, including the tyrosinase inhibitor of the first embodiment of the present invention, based on the total mass of the whitening toner, the tyrosinase inhibitor The addition amount of agent is 0.01~8%, preferably 0.1-5%, for example: the addition amount of described tyrosinase inhibitor can be 0.5%, 1%, 1.5%, 2.5%, 3%, 3.5%, 4%, 4.5%, 5.5%, 6%, 7%, etc. In the present invention, by adding a suitable content of the tyrosinase inhibitor of the present invention, the activity of tyrosinase can be inhibited, so that the whitening skin lotion of the present invention has an excellent whitening effect. When the addition amount of tyrosinase inhibitor is less than 0.01%, the amount of melanin content reduction is little, can not play the effect of whitening; When the addition amount of tyrosinase inhibitor is greater than 8%, tyrosinase inhibitor The content is too high, the cost is too high, and the...

no. 3 approach

[0062] The third embodiment of the present invention provides a preparation method of the whitening skin lotion according to the second embodiment, including the step of mixing the components of the cosmetic.

[0063] Specifically, the preparation method of described whitening and fine skin water comprises the following steps:

[0064] Step 1, adding water, humectant, thickener, optional chelating agent, pH regulator and some preservatives into a stirring pot, stirring and heating to 75-85°C;

[0065] Step 2, cooling to 40-50°C, adding solubilizer, fragrance, tyrosinase inhibitor, skin conditioner, optional antioxidant and remaining preservative and stirring evenly;

[0066] Step 3. Cool to 30-40°C, discharge after passing the inspection, and let stand for 12-48 hours;

[0067] Step 4. After passing the inspection, subpackage, pack, re-inspect, and put the finished product into storage.

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Abstract

The invention provides a tyrosinase inhibitor, whitening and skin refining lotion and a preparation method thereof. The tyrosinase inhibitor is prepared from 0.2 to 99 percent of radix puerariae extracts and 1 to 99.8 percent of saffron extracts based on the total mass of the tyrosinase inhibitor. The inhibition effect of the tyrosinase inhibitor on the activity of the tyrosinase is excellent; noside effect exists on the human body. Further, the recipe of the whitening and skin refining lotion is mild; the activity of the tyrosinase can be effectively inhibited, so that the whitening effect is achieved.

Description

technical field [0001] The invention relates to a tyrosinase inhibitor, whitening skin lotion and a preparation method thereof, belonging to the field of cosmetics. Background technique [0002] Tyrosinase is a key enzyme in the process of melanin formation. Tyrosinase (tyrosinase) has a variety of characteristic catalytic activities. It can be used not only as tyrosine hydroxylase, dopa oxidase, but also as 5,6-dihydroxyindole oxidase, which plays a role in the process of melanin production. play a vital role. , tyrosinase converts tyrosine to dopa through monophenolase activity, and converts dopa to dopaquinone through diphenolase activity, which are the key rate-limiting steps in tyrosinase-catalyzed melanin formation. It is generally believed that tyrosinase activity plays a major role in skin melanin deposition. The role of whitening agents is to reduce the production of melanin and achieve the effect of whitening the skin by inhibiting the activity of tyrosinase or ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/9794A61Q19/02
CPCA61K2800/782A61Q19/02A61K8/9789A61K8/9794
Inventor 杨登亮戴嘉彬刘德海李华真江兰兰林盛杰张伟杰张楚标
Owner GUANGZHOU KENENG COSMETICS RES CO LTD
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