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Cartilage injury degree assessment method based on multimodality magnetic resonance

A technique of cartilage damage and magnetic resonance, applied in medical science, veterinary instruments, sensors, etc., can solve problems such as long test time

Inactive Publication Date: 2019-05-03
THE SECOND PEOPLES HOSPITAL OF SHENZHEN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When evaluating the degree of cartilage damage, MRI is mostly used for imaging analysis. MRI imaging is clear and without any radiation, but it takes a long time to test. T2mapping imaging is one of the most widely used cartilage MR physiological imaging technologies. T2mapping imaging By measuring the T2 relaxation time of articular cartilage to reflect the biochemical changes of articular cartilage, the present invention aims to study the degree of reflection of magnetic resonance imaging T2mapping on changes in cartilage tissue, so as to determine the reliability of T2mapping for detecting the degree of cartilage damage

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The present invention provides a technical solution: a method for evaluating the degree of cartilage damage based on multimodal magnetic resonance, the method comprising the following steps:

[0020] S1: Prepare 15 healthy adult miniature rams, randomly divide them into 3 groups, 5 in each group, and name them as group A, group B and group C respectively;

[0021] S2: The three groups of rams were modeled separately, and then the anterior cruciate ligament of the left knee joint of the rams in group A was excised for osteoarthritis modeling, and the left knee joint of the rams in group B was avulsed Bone fracture modeling was performed on the left knee joint of the rams in group C; bone contusion modeling was performed;

[0022] S3: Multimodal magnetic resonance cartilage imaging, and then delayed gadolinium-enhanced magnetic resonance cartilage imaging was performed on the miniature rams in group A, group B, and group C using T2mapping technology based on multimodal ma...

Embodiment 2

[0031] The present invention provides a technical solution: a method for evaluating the degree of cartilage damage based on multimodal magnetic resonance, the method comprising the following steps:

[0032] S1: Prepare 15 healthy adult miniature rams, randomly divide them into 3 groups, 5 in each group, and name them as group A, group B and group C respectively;

[0033] S2: The three groups of rams were modeled separately, and then the anterior cruciate ligament of the left knee joint of the rams in group A was excised for osteoarthritis modeling, and the left knee joint of the rams in group B was avulsed Bone fracture modeling was performed on the left knee joint of the rams in group C; bone contusion modeling was performed;

[0034] S3: Multimodal magnetic resonance cartilage imaging, and then delayed gadolinium-enhanced magnetic resonance cartilage imaging was performed on the miniature rams in groups A, B, and C using T2mapping technology based on multimodal magnetic reso...

Embodiment 3

[0043] The present invention provides a technical solution: a method for evaluating the degree of cartilage damage based on multimodal magnetic resonance, the method comprising the following steps:

[0044] S1: Prepare 15 healthy adult miniature rams, randomly divide them into 3 groups, 5 in each group, and name them as group A, group B and group C respectively;

[0045] S2: The three groups of rams were modeled separately, and then the anterior cruciate ligament of the left knee joint of the rams in group A was excised for osteoarthritis modeling, and the left knee joint of the rams in group B was avulsed Bone fracture modeling was performed on the left knee joint of the rams in group C; bone contusion modeling was performed;

[0046] S3: Multimodal magnetic resonance cartilage imaging, and then delayed gadolinium-enhanced magnetic resonance cartilage imaging was performed on the miniature rams in group A, group B, and group C using T2mapping technology based on multimodal ma...

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Abstract

The invention discloses a cartilage injury degree assessment method based on multimodality magnetic resonance. The cartilage injury degree assessment method comprises the steps of S1, preparing 15 healthy adult small rams; S2, respectively constructing moulds on 3 groups of the rams; S3, imaging the multimodality magnetic resonance cartilage; S4, recording number; S5, performing tissue analysis; and S6, performing data analysis. Through the three groups namely A, B and C of the rams, the fluctuating change of T2 value of the rams at the 0th week, the 3rd week, the 6th week and the 9th week andthe content of glycosaminoglycan in the articular cartilage (GAG), the correlation analysis is performed on the content of collagen, so that the obtained T2 mapping technique is used for expressing the accuracy of the cartilage injury.

Description

technical field [0001] The invention relates to the field of multimodal magnetic resonance, in particular to a cartilage damage assessment method based on multimodal magnetic resonance. Background technique [0002] Nuclear magnetic resonance imaging (MRI) uses the principle of nuclear magnetic resonance (NMR for short), according to the different attenuation of the released energy in different structural environments inside the material, and detects the emitted electromagnetic waves by applying a gradient magnetic field. Knowing the position and type of the atomic nuclei that make up the object can be used to draw a structural image inside the object. When evaluating the degree of cartilage damage, MRI is mostly used for imaging analysis. MRI imaging is clear and without any radiation, but it takes a long time to test. T2mapping imaging is one of the most widely used cartilage MR physiological imaging technologies. T2mapping imaging By measuring the T2 relaxation time of a...

Claims

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Application Information

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IPC IPC(8): A61B5/055A61D1/00
Inventor 段莉王大平徐晓李兴福熊建义欧阳侃黄江鸿邓志钦蒯声政
Owner THE SECOND PEOPLES HOSPITAL OF SHENZHEN
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