Medical cooling polymer hydrogel cold therapy patch

A technology of polymer hydrogel and cold therapy, which is applied in other medical devices, cooling appliances for therapeutic treatment, medical preparations containing active ingredients, etc., can solve the problem of limited cooling range of hydrogel cold therapy patches, etc. Achieve good biodegradability and compatibility, not easy to evaporate, and improve the effect of surface touch

Inactive Publication Date: 2019-05-03
余标
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing hydrogel cold therapy patches have limited cooling range

Method used

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  • Medical cooling polymer hydrogel cold therapy patch

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preparation example Construction

[0028] A kind of medical cooling polymer hydrogel cold therapy paste, its preparation method comprises the following steps:

[0029](1) In a reaction kettle equipped with a reflux condenser, a dropping funnel and a thermometer, add half of the total amount of pure water and picoline, then add selenium dioxide, react at 60°C for 1~2h, and then add dropwise Methane iodide, the reaction kettle and the dropping funnel should be sealed with shading. After 1 hour of reaction, add PVA, silk protein, purple sweet potato powder, and xanthan gum to raise the temperature to 80°C, and stir for 30-60 minutes to obtain mixture A; (2 ) Add half of the total amount of sodium hydroxide, mixture A, polyphosphazene, calcium chloride and sodium tetraborate into the reaction kettle, mix and stir at room temperature, add polyethylene glycol dropwise within 8 minutes, and finish adding dropwise within 6 minutes Polypropylene glycol, then add the remaining sodium hydroxide, the remaining purified wat...

Embodiment 2

[0031] A medical cooling polymer hydrogel cold therapy patch, which is mainly prepared from the following raw materials in parts by weight:

[0032] 13~17 parts of polyphosphazene, 6.3 parts of selenium dioxide, 13 parts of silk protein, 7 parts of purple potato powder, 21 parts of calcium chloride, 9 parts of xanthan gum, 67 parts of purified water, 5 parts of picoline, polyethylene 19 parts of glycol, 2.1 parts of methyl iodide, 8.5 parts of sodium hydroxymethyl cellulose, 33 parts of PVA, 1.3 parts of sodium tetraborate, 1.6 parts of sodium hydroxide, 5.3-8.1 parts of polypropylene glycol, 3.5-5.3 parts of Chinese medicine mixture.

[0033] Further, the polyethylene glycol is PEG-600.

[0034] Further, the degree of polymerization of the PVA is 3500-4000, the degree of alcoholysis is 85-99.7 (mol)%, and the content of -COONa group in the PVA molecule is 0.95-1.2 mol / kg.

[0035] Further, the traditional Chinese medicine mixture is 3.7 parts by weight of borneol, 2.4 parts ...

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Abstract

The present invention discloses a medical cooling polymer hydrogel cold therapy patch and belongs to the technical field of medical polymer materials. The medical cooling polymer hydrogel cold therapypatch is mainly prepared from the following raw materials: polyphosphazene, selenium dioxide, silk fibroin, purple sweet potato powder, calcium chloride, xanthan gum, purified water, methylpyridine,polyethylene glycol, methyl iodide, sodium carboxymethyl cellulose, PVA, sodium tetraborate, sodium hydroxide, polypropylene glycol and a mixture of traditional Chinese medicines. The anti-aging hydrogel cold therapy patch is simple in preparation technology, suitable in gel strength and long in duration of cold compress curative effects, an ideal cold compress patch product, and suitable for large-scale production applications. A hydrogel layer combines traditional hydrogel cold compress and calcium chloride cold compress, and is good in auxiliary treatment effects, free of any side effects and easy to use.

Description

technical field [0001] The invention relates to the technical field of medical polymer materials, in particular to a medical cooling polymer hydrogel cold therapy patch. Background technique [0002] The cold compress is improved according to the traditional cold compress methods (such as cold water, ice water, alcohol, etc.), and the TDDS new drug release system prepared on the basis of polymer gel is the core. It consists of a backing layer, a gel layer, and an anti-aging sticky layer composition. Through the vaporization of the water contained in the polymer gel and the natural cooling ingredients to take away the heat, local cooling can be achieved. The drug ingredients in it are combined with the hydrogel, and through hydration, the drug ingredients can quickly penetrate the fat layer. It penetrates into the subcutaneous tissue, directly reaches the lesion, acts on the affected area, and achieves the effects of cold compress to relieve pain, percutaneous absorption, an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/70A61P19/02A61P19/04A61P19/06A61P21/00A61P29/00A61M37/00A61F7/02A61K31/045A61K35/413
Inventor 余标
Owner 余标
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