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Adsorption device, adsorption microscope detection device and laser scanning microscope

A detection device and microscope technology, which is applied in the field of laser scanning microscopes, can solve the problems of high resolution requirements for three-dimensional nonlinear laser scanning imaging, being easily affected by vibration, and affecting imaging quality, etc.

Pending Publication Date: 2019-05-14
BEIJING CHAOWEIJING BIOLOGICAL TECH CO LTD
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Problems solved by technology

[0004] However, the detection device based on the robotic arm in the above-mentioned 3D nonlinear laser scanning microscope has a large volume and the probe corresponds to a large skin area of ​​the human body, so that the detection device is easily affected by the shaking of the human body during specific operations, while the 3D non-linear laser scanning microscope The resolution requirement of linear laser scanning imaging is generally high, and it is easily affected by vibration, thus affecting the imaging quality

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  • Adsorption device, adsorption microscope detection device and laser scanning microscope
  • Adsorption device, adsorption microscope detection device and laser scanning microscope
  • Adsorption device, adsorption microscope detection device and laser scanning microscope

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Embodiment Construction

[0041] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments It is a part of embodiments of the present invention, but not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention.

[0042]The existing detection equipment based on fluorescence signals and second harmonic signals to obtain the morphology of biological cells is mainly a three-dimensional nonlinear laser scanning microscope. At present, the laser scanning microscope is mainly a laser scanning microscope based on a mechanical arm, namely The detection device of th...

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Abstract

The embodiment of the invention provides an adsorption device, an adsorption microscope detection device and a laser scanning microscope. The adsorption device comprises a shell body, a sucking disc,a coverslip and a motion device, the sucking disc is embedded in a sucking disc hole, and the coverslip is fixed to a sealing opening of the sucking disc to form inner closed space and outer adsorption space; a fixed bracket of the motion device is fixed to the side wall of the shell body, and relative sliding connection between a limit block and the fixed bracket drives a minitype microscope probe to move up and down. According to the adsorption device, the adsorption microscope detection device and the laser scanning microscope, the outer adsorption space making the adsorption device adsorbed on the skin and the inner closed space used for arrangement of the probe are formed by the shell body, the sucking disc and the coverslip, so that after the adsorption device is adsorbed on the skin, the minitype microscope probe outputs an inner signal and receives an external signal by transmitting through the coverslip, the whole adsorption device is miniaturized, it is avoided that the probeis subjected to vibration influence caused by moving of a living body, and the adsorption device is simple in operation and convenient to use.

Description

technical field [0001] The embodiments of the present invention relate to the technical field of laser scanning microscopes, in particular to an adsorption device, an adsorption microscope detection device and a laser scanning microscope. Background technique [0002] With the continuous development of medicine and biology, people have made significant progress in the study of cell morphology, tissue structure or fiber state in the stomach of animals, especially through the excitation of pulsed laser radiation in the near-infrared region and by suitable high sensitivity. Receiver detection, obtain fluorescence signal and second harmonic signal, so as to obtain the relevant technology of living biological cell morphology, and achieved remarkable results. [0003] Based on fluorescence signals, second harmonic signals and CARS (Coherent anti-Stokes Raman Scattering, correlated anti-Stokes Raman scattering) signals, related detection equipment to obtain biological cell morpholo...

Claims

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Application Information

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IPC IPC(8): A61B5/00
Inventor 吴润龙王爱民江文茂胡炎辉吴丹磊徐阳阳程和平
Owner BEIJING CHAOWEIJING BIOLOGICAL TECH CO LTD
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