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Separated adsorption device, microscope detection device and laser scanning microscope

A technology of adsorption device and detection device, which is applied in the field of laser scanning microscope, can solve the problems of high resolution requirement of three-dimensional nonlinear laser scanning imaging, easy to be affected by vibration, detection device is easily affected by human body shaking, etc.

Pending Publication Date: 2019-05-14
BEIJING CHAOWEIJING BIOLOGICAL TECH CO LTD
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Problems solved by technology

[0004] However, the detection device based on the robotic arm in the above-mentioned 3D nonlinear laser scanning microscope has a large volume and the probe corresponds to a large skin area of ​​the human body, so that the detection device is easily affected by the shaking of the human body during specific operations, while the 3D non-linear laser scanning microscope The resolution requirement of linear laser scanning imaging is generally high, and it is easily affected by vibration, thus affecting the imaging quality

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  • Separated adsorption device, microscope detection device and laser scanning microscope
  • Separated adsorption device, microscope detection device and laser scanning microscope
  • Separated adsorption device, microscope detection device and laser scanning microscope

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Embodiment Construction

[0041] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments It is a part of embodiments of the present invention, but not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention.

[0042]The existing detection equipment based on fluorescence signals and second harmonic signals to obtain the morphology of biological cells is mainly a three-dimensional nonlinear laser scanning microscope. At present, the laser scanning microscope is mainly a laser scanning microscope based on a mechanical arm, namely The detection device of th...

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Abstract

The embodiment of the invention provides a separated adsorption device, a microscope detection device and a laser scanning microscope, wherein the separated adsorption device comprises an outer shell,a base with a sucker, a cover glass and a moving device, the sucker is embedded into a sucker hole, and the cover glass is fixed at a sucker sealing opening to form a built-in space and an outer adsorption space; a fixed bracket of the moving device is fixed on the side wall of the outer shell, and a limiting block is relatively and slidably connected with the fixed bracket to drive a micro microscope probe to move up and down. According to the separated adsorption device, the microscope detection device and the laser scanning microscope, the outer adsorption space for adsorbing the adsorption device on skin and the built-in space for arranging the probe are formed by the outer shell, the sucker and the cover glass, so that after the device is adsorbed on skin, the micro microscope probeoutputs an internal signal and receives an external signal through the cover glass, the whole device is miniaturized, the vibration influence on the probe caused by the activity of a living body is avoided, and the micro microscope probe is simple to operate and convenient to use.

Description

technical field [0001] Embodiments of the present invention relate to the technical field of laser scanning microscopes, in particular to a separate adsorption device, a microscope detection device and a laser scanning microscope. Background technique [0002] With the continuous development of medicine and biology, people have made significant progress in the study of cell morphology, tissue structure or fiber state in the stomach of animals, especially through the excitation of pulsed laser radiation in the near-infrared region and by suitable high sensitivity. Receiver detection, obtain fluorescence signal and second harmonic signal, so as to obtain the relevant technology of living biological cell morphology, and achieved remarkable results. [0003] Based on fluorescence signals, second harmonic signals and CARS (Coherent anti-Stokes Raman Scattering, correlated anti-Stokes Raman scattering) signals, related detection equipment to obtain biological cell morphology occup...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00
Inventor 吴润龙王爱民江文茂程和平
Owner BEIJING CHAOWEIJING BIOLOGICAL TECH CO LTD
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