Cardiac adenocarcinoma auxiliary diagnostic kit related to a group of genes

A technique for adenocarcinoma of the cardia and auxiliary diagnosis, which is applied in the fields of biomedicine and molecular biology, and can solve the problems of difficult clinical practice, low specificity and low sensitivity.
CN110187112BActive Publication Date: 2020-02-11THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV
Publication Date
2020-02-11

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Abstract

The invention relates to a cardia adenocarcinoma auxiliary diagnosis kit related to a group of genes, belongs to the technical field of biomedicine and molecular biology, and particularly relates to an ELISA kit for auxiliary diagnosis of cardia adenocarcinoma. The kit comprises a solid phase carrier and six antibodies which are respectively coated on the solid phase carrier, wherein the six antibodies are as follows: BCL2L1 antibody, DLC1 antibody, CDKN2A antibody, CDKN2B antibody, NRG1 antibody, ErbB4 antibody. Experiments prove that the group of related gene expression product has high expression in the serum of a cardia adenocarcinoma patient, the expression level of the related gene in the human serum is detected by the ELISA kit, and the detection result can be used for auxiliary diagnosis of the cardia adenocarcinoma such as early-onset screening, prognosis evaluation and the like, and the ELISA kit for auxiliary diagnosis of cardia adenocarcinoma has profound clinical significance and important popularization and application prospect.
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Description

technical field

[0001] The invention relates to a kit for early screening or auxiliary diagnosis of cardia adenocarcinoma by detecting a group of gene expression levels, belonging to the technical fields of biomedicine and molecular biology. Background technique

[0002] Gastric Cardia Adenocarcinoma (GCA) is a malignant tumor located in the anatomical position of the human cardia, which endangers people's quality of life and life, and brings a heavy burden to the patient's family and the country. In the past few decades, the incidence of GCA in high-incidence areas in my country has been increasing year by year, increasing by seven times, and the incidence of GCA is higher than other malignant tumors. Henan Province in my country has the highest incidence rate of cardia adenocarcinoma in the world, reaching 190 / 100,000, and the incidence rate is still rising.

[0003] Previous studies have identified several risk factors associated with the development of GCA, including li...

Claims

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