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Composition for alleviating nasal dryness, preparation method and application method thereof

A nasal dryness and composition technology, which is applied in the medical field, can solve the problems of aggravating nasal dryness, lack of dry rhinitis material components, and impracticability, and achieve the effects of preventing excessive edema, scientific prescription proportioning, and high practicability

Active Publication Date: 2021-11-09
WENZHOU MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The method of removing external causes is the most reliable, but it is often impossible to achieve it in real life without contacting external stimuli
At present, most of the nasal cavity care products on the market have the functions of inhibiting the growth of nasal bacteria, inhibiting the secretion of inflammatory factors, shrinking mucosal blood vessels, and anti-allergic effects. Nasal drops can even worsen symptoms of nasal dryness

Method used

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preparation example Construction

[0034] The present invention also provides a preparation method of the composition for alleviating nasal dryness, comprising the following steps:

[0035] A. Mix lubricant, moisturizing agent, microcirculation improving agent and skin repairing agent, add about 50 parts by weight of distilled water and stir evenly at normal temperature and pressure;

[0036] B. Add an osmotic regulator to the mixture in step A, then add distilled water to 100 parts by weight, stir at normal temperature and pressure to dissolve.

[0037] The composition of the present invention is different from common nasal drops in the prior art, which are usually based on the removal of pathogens as the starting point of research and development, or common nursing products to inhibit the growth of nasal bacteria, inhibit the secretion of inflammatory factors, shrink mucosal blood vessels, and resist allergies. , and starting from improving the nasal environment, lubricants (glycerol, butylene glycol, medic...

Embodiment 1

[0040] A composition for relief of nasal dryness comprising glycerol, hyaluronic acid, sodium chloride, dextran 40, dipotassium glycyrrhizinate and allantoin.

[0041] Prepare 100g of this composition, and take each component by weight as follows:

[0042] Glycerol: 10g;

[0043] Hyaluronic acid: 0.25g;

[0044] Sodium chloride: 12g;

[0045] Dextran 40: 0.1g;

[0046] Allantoin: 0.2g;

[0047] Dipotassium glycyrrhizinate: 0.2g;

[0048] Add distilled water to 100g.

[0049] The preparation process of the composition is:

[0050] First add about 50g of distilled water to the weight of glycerol, hyaluronic acid, dextran 40, allantoin, and dipotassium glycyrrhizinate and stir evenly at room temperature and pressure, then add sodium chloride, add distilled water to 100g, and stir After standing for 10 minutes, it becomes the original solution, and when used, it is diluted 100 times with normal saline or mineral water to obtain the finished product.

Embodiment 2

[0052] A composition for relieving nasal dryness, comprising butylene glycol, aloe extract, sodium chloride, dextran 40, allantoin.

[0053] Prepare 100g of this composition, and take each component by weight as follows:

[0054] Butanediol: 5g;

[0055] Aloe Vera Extract: 0.15g;

[0056] Sodium chloride: 15g;

[0057] Dextran 40: 0.1g;

[0058] Allantoin: 0.1g;

[0059] Add distilled water to 100g.

[0060] The preparation process of the composition for alleviating nasal dryness is as follows:

[0061] First add about 50 g of distilled water to the above-mentioned butanediol, aloe extract, sodium chloride, dextran 40, and allantoin and stir evenly at normal temperature and pressure, then add sodium chloride, add distilled water to 100 g, and stir for 10 Minutes, after standing still, it becomes the original solution, which is diluted 100 times with normal saline or mineral water, and the finished product is sprayed or dropped in the nasal cavity.

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Abstract

The invention discloses a composition for alleviating nasal dryness, the composition includes a lubricant, a moisturizing agent, an osmotic regulator, a microcirculation improving agent and a skin repairing agent, and every 100 parts by weight of the composition contains the following parts by weight Lubricants: 5-10 parts; Moisturizers: 0.1-0.25 parts; Osmotic regulators: 10-15 parts; Microcirculation improvers: 0.1 parts; Skin repair agents: 0.1-0.5 parts ; The balance is distilled water. The composition of the present invention can give full play to its excellent lubricating and moisturizing function, while maintaining the appropriate humidity of the nasal environment, it is conducive to nasal ventilation; at the same time, the microcirculation improving agent and skin repairing agent can improve the microcirculation caused by dryness in the nasal cavity. Wounds, keep the nasal mucosa intact and healthy, and can improve a variety of nasal problems. The composition of the invention has safe components, high practicability, scientific prescription ratio and easy popularization.

Description

technical field [0001] The invention relates to the field of medical technology, in particular to a composition for alleviating nasal dryness, a preparation method and an application method thereof. Background technique [0002] Rhinitis sicca is generally believed to be caused by long-term stimulation of external physical or chemical substances, such as long-term mechanical stimulation of dust, the influence of overheated and overdry air, etc. The disease is a common occupational chronic rhinitis. When rhinitis sicca is not treated in time and affects the olfactory mucosa, olfactory disturbance will occur, affecting mental and physical development, and respiratory obstruction will cause brain hypoxia and cause dizziness and lethargy. In addition, due to poor exhalation, breathing through the mouth will directly stimulate the pharynx and cause pharyngitis. If things go on like this, the lips will thicken and the teeth will develop outwards, resulting in facial deformities. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/08A61K47/10A61K47/22A61K47/26A61K47/28A61K47/36A61K47/46A61P11/02
CPCA61K9/0043A61K9/08A61K47/10A61K47/22A61K47/26A61K47/28A61K47/36A61K47/46A61P11/02
Inventor 周铁丽陈涛曹建明方人驰喻凯航
Owner WENZHOU MEDICAL UNIV
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