Method for studying mechanism of gynura divaricata influencing inflammatory factors in type-II diabetic mice

A technology of inflammatory factors and Baizicai, which is applied in the field of diabetes research and can solve problems that have not been studied in depth

Inactive Publication Date: 2019-09-27
GUANGXI UNIV OF CHINESE MEDICINE
View PDF4 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Baizicai has the function of protecting the liver, but the mechanism of fresh

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for studying mechanism of gynura divaricata influencing inflammatory factors in type-II diabetic mice
  • Method for studying mechanism of gynura divaricata influencing inflammatory factors in type-II diabetic mice
  • Method for studying mechanism of gynura divaricata influencing inflammatory factors in type-II diabetic mice

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0047] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0048] This specific embodiment adopts following technical scheme: its operating steps are as follows:

[0049] 1. Prepare experimental materials

[0050] 1.1. Experimental drug preparation:

[0051] The experimental drug was collected in Guigang, Guangxi. It is the whole plant of the genus Panax notoginseng in the Compositae family. It was identified by Associate Professor Guo Min from the Department of Medicinal Plants, Guangxi University of Traditional Chi...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Lengthaaaaaaaaaa
Login to view more

Abstract

The invention discloses a method for studying the mechanism of gynura divaricata influencing inflammatory factors in type-II diabetic mice, and relates to diabetes research. The method comprises the following steps: adaptively feeding 50 mice for one week, then randomly dividing into a blank control group and a model group, and feeding with normal feed and high-fat and high-sugar feed; after feeding for 4 weeks, fasting and but feeding with water for 12h overnight, weighing and marking; and injecting STZ for three days, fasting and but feeding with water for 12h overnight, firstly experimenting in advance by using a glucometer and test paper, then monitoring the tail blood glucose of the mice by using a microglucometer, and determinating, wherein the fasting blood glucose being greater than or equal to 11.1mmol/L is used as a model standard for the type-II diabetes. Type-II diabetes mouse models are replicated through coordination of a high-fat diet and intraperitoneal injection of streptozotocin, and influence on the inflammatory factors in the mice after intervention of the fresh gynura divaricate is evaluated, so that a clearer theory is provided for the treatment of the type-II diabetes by the gynura divaricate and further development of a Guangxi-characteristic Chinese herbal medicine.

Description

technical field [0001] The invention relates to the technical field of diabetes research, in particular to a research method for the mechanism of the influence of Chinese cabbage on inflammatory factors in type II diabetic mice. Background technique [0002] With the improvement of people's living standards and changes in lifestyle, the number of diabetic patients is also increasing rapidly, especially young people who eat too much, lack of exercise, and the trend of diabetes rejuvenation is obvious. According to the press release of Beijing Diabetes Prevention Association in 2015, by 2013 The number of patients in my country accounts for about 1 / 3 of the world's total. Diabetes has become one of the diseases with the highest morbidity and mortality in the world, and its high mortality, disability rate and high cost of treating diabetes and its complications, It has caused a serious social and economic burden to the country and the people. China is a country with a large popu...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K49/00A61K36/28A61P3/10
CPCA61K36/28A61K49/0008A61P3/10
Inventor 韦乃球
Owner GUANGXI UNIV OF CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap