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Postpartum stasis removing tablet and preparation method thereof

A technology of removing blood stasis and angelica, which is applied in the field of postpartum blood stasis removing tablets and its preparation, can solve the problems of incomplete extraction of active ingredients of medicinal materials, unstable drug quality, and easy volatilization of volatile oils, and achieve easy industrial production, easy operation, and guaranteed curative effect Effect

Inactive Publication Date: 2019-10-18
广西万寿堂药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the volatile oil in the original preparation process is easy to volatilize during production and storage, the quality of the drug is likely to be unstable, and the active ingredients of the medicinal material are not fully extracted, and the efficacy of the drug is difficult to guarantee

Method used

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  • Postpartum stasis removing tablet and preparation method thereof
  • Postpartum stasis removing tablet and preparation method thereof
  • Postpartum stasis removing tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] R1. Take Motherwort, Angelica, Rhizoma Chuanxiong and Paojiang respectively, clean and dry;

[0055] R2. Weigh the components by the following parts by weight: Motherwort 1248g, Angelica 156g, Rhizoma Chuanxiong 178g, Paojiang 78g;

[0056] R3. Take 20g each of motherwort, angelica, and chuanxiong, and grind them into fine powder for later use;

[0057] R4. Take the remaining Angelica sinensis, Rhizoma Chuanxiong and Paojiang respectively and grind them to 30 meshes, mix them evenly, add 6 times the amount of water to extract the volatile oil for 5 hours, collect the volatile oil, and use the distilled water and medicinal residue for later use;

[0058]R5. Take the volatile oil in step R4 to prepare volatile oil inclusion complexes: weigh and take hydroxypropyl-β-cyclodextrin according to the ratio of hydroxypropyl-β-cyclodextrin: volatile oil=6:1 (g:ml) ;Take purified water equivalent to 8 times the amount of hydroxypropyl-β-cyclodextrin and heat it to 90°C; add hydro...

Embodiment 2

[0065] R1. Take Motherwort, Angelica, Rhizoma Chuanxiong and Paojiang respectively, clean and dry;

[0066] R2. Weigh the components by the following parts by weight: Motherwort 1248g, Angelica 156g, Rhizoma Chuanxiong 178g, Paojiang 78g;

[0067] R3. Take 20g each of motherwort, angelica, and chuanxiong, and grind them into fine powder for later use;

[0068] R4. Take the remaining Angelica sinensis, Ligusticum chuanxiong and Paojiang respectively and grind them to 50 meshes, mix them evenly, add 6 times the amount of water to extract the volatile oil for 5 hours, collect the volatile oil, and use the distilled water and medicinal residue for later use;

[0069] R5. Take the volatile oil in step R4 to prepare volatile oil inclusion complexes: weigh and take hydroxypropyl-β-cyclodextrin according to the ratio of hydroxypropyl-β-cyclodextrin: volatile oil=6:1 (g:ml) ;Heat purified water equivalent to 8 times the amount of hydroxypropyl-β-cyclodextrin to 100°C; add hydroxypropy...

Embodiment 3

[0076] R1. Take Motherwort, Angelica, Rhizoma Chuanxiong and Paojiang respectively, clean and dry;

[0077] R2. Weigh the components by the following parts by weight: Motherwort 1248g, Angelica 156g, Rhizoma Chuanxiong 178g, Paojiang 78g;

[0078] R3. Take 20g each of motherwort, angelica, and chuanxiong, and grind them into fine powder for later use;

[0079] R4. Take the remaining Angelica sinensis, Ligusticum chuanxiong and Paojiang and grind them to 40 meshes, mix them evenly, add 6 times the amount of water to extract the volatile oil for 5 hours, collect the volatile oil, and use the distilled water and medicinal residue for later use;

[0080] R5. Take the volatile oil in step R4 to prepare volatile oil inclusion complexes: weigh and take hydroxypropyl-β-cyclodextrin according to the ratio of hydroxypropyl-β-cyclodextrin: volatile oil=6:1 (g:ml) ;Take purified water equivalent to 8 times the amount of hydroxypropyl-β-cyclodextrin and heat it to 95°C; add hydroxypropyl-...

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Abstract

The invention discloses a postpartum stasis removing tablet and a preparation method thereof. The postpartum stasis removing tablet is mainly prepared from, by weight, 1248 parts of herba leonuri, 156parts of angelica sinensis, 178 parts of rhizome of chuanxiong and 78 parts of rhizoma zingiberis preparata. The preparation method effectively reduces the volatilization of volatile oil during production and storage, reduces the loss of active ingredients, increases the stability of drugs, overcomes the shortcomings that the volatile oil is volatilized easily, the drugs are instable, and the loss of the active ingredients is large, increases the content of the active ingredients in extracts, and ensures the curative effect of the product; clinical test results show that the product has a better curative effect on treating unthorough removal of postpartum extravasated blood, is safe and reliable to take, and has no adverse side effects.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a postpartum stasis-removing tablet and a preparation method thereof. Background technique [0002] Postpartum Zhuyu Tablets are recorded in the Ministry of Health's Drug Standards for Traditional Chinese Medicine Prescriptions Volume 15 WS3-B-2882-98. It is prepared from motherwort, angelica, Chuanxiong and Paojiang four traditional Chinese medicines and auxiliary materials. It has the function of promoting blood circulation and regulating menstruation. The function of blood stasis and pain relief is used for postpartum congestion and abdominal pain in young women. The original preparation process of postpartum Zhuyu Tablets is that 20g of motherwort, angelica and chuanxiong in the prescription are crushed into fine powder and used as medicine, the remaining angelica, chuanxiong and paojiang extract the volatile oil, and then the dregs and the remaining motherwort are decocted with wate...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/28A61K47/69A61K36/9068A61P15/00
CPCA61K9/28A61K36/232A61K36/236A61K36/533A61K36/9068A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K47/6951A61P7/04A61P15/00A61P29/00A61K2300/00
Inventor 韦德韦锦阳毛金玲
Owner 广西万寿堂药业有限公司
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