A kind of effective part of Dendrobium melon and its preparation method and application

An effective part, the technology of Dendrobium melon, is applied in the direction of medical preparations, applications, and pharmaceutical formulas containing active ingredients, which can solve the problem that the effective part and composition of the extract cannot be clarified, and achieve strong inhibition of α-glucosidase activity , strong antioxidant capacity, strong effect on HT22 cell damage
CN110354205BActive Publication Date: 2021-11-16SUN YAT SEN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SUN YAT SEN UNIV
Publication Date
2021-11-16

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Abstract

The invention relates to the technical field of traditional Chinese medicines, and specifically discloses an effective fraction of Dendrobium melon, a preparation method and application thereof. The main secondary metabolite compound type of the effective part of Dendrobium melon is glycoside compound. The main glycoside components of the effective part of Dendrobium officinalis are pimarane-type monoglycoside, flickinflimoside B, diglycoside fliflidioside A, (+)-syringaresin-O-β-D-glucopyranoside and the like. In vitro activity studies show that the effective fraction of Dendrobium melonii of the present invention has good DPPH free radical and OH free radical scavenging activity, α-glucosidase inhibitory activity, and inhibitory activity of glutamate-induced HT22 cell damage. The effective part of Dendrobium candidum can be developed into an auxiliary drug or health care product for treating Alzheimer's disease, liver protection, type II diabetes and other diseases.
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Description

technical field

[0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a Dendrobium melon (Dendrobium officinalis) Flickingeria fimbriata ) effective part and its preparation method and application. Background technique

[0002] Dendrobium with melon, that is, golden Dendrobium with tassels ( Flickingeria fimbriata ) for Orchid ( Orchidaceae ) Dendrobium ( Flickingeria ) plants, mainly produced in Guangdong (Meizhou area), Guangxi, Hainan, Yunnan, Guizhou and other places. The traditional Chinese medicine Dendrobium candidum is Dendrobium candidum ( Flickingeria fimbriata ) dry whole plant with pseudobulbs, also known as Dendrobium with Melon. The traditional Chinese medicine Dendrobium officinale is recorded in the "Guangdong Provincial Standards of Chinese Medicinal Materials". It tastes sweet and slightly cold. It returns to the stomach, lung and kidney meridians. It is used for yin deficiency and body fluid deficienc...

Claims

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