Unlock instant, AI-driven research and patent intelligence for your innovation.

Cosmetic skincare compositions

A cosmetic composition and compound technology, applied in the field of cosmetic treatment, can solve the problems of skin barrier damage, low stratum corneum quality, damage and the like

Active Publication Date: 2019-11-01
BOOTS PURE DRUG CO LTD
View PDF5 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A consequence of this inflammation is increased proliferation of keratinocytes, followed by their poor maturation and differentiation, leading to lower quality stratum corneum and consequent disruption and / or damage to the skin barrier

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Cosmetic skincare compositions
  • Cosmetic skincare compositions
  • Cosmetic skincare compositions

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0150] Interleukin-6 (IL-6) test

[0151] The biological activity of interleukin-6 (IL-6) in skin cells was measured. IL-6 is a cytokine and is used as a biomarker of inflammation. Skin cells (keratinocytes or fibroblasts) were subjected to UV stress to induce an IL-6 response in the presence of an active substance or a mixture of active substances to determine that the active substance or mixture of active substances inhibited IL-6. 6 Responsive activity.

[0152] The cultured skin cells (keratinocytes or fibroblasts) were seeded in a 96-well plate at a density of 5000 cells per well in cell growth medium with supplements, and incubated at 37°C for 24 hours. Determination of cell numbers for plating purposes is performed according to standard methods known in the art.

[0153] After incubation, the cell growth medium was replaced with 100 μl of PBS without calcium and magnesium and containing the desired relevant concentration of active substance(s). Controls included u...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

According to the present invention there is provided a cosmetic composition comprising: (i) a polyphenolic antioxidant agent; and (ii) a sphingosine compound.

Description

technical field [0001] The present invention relates to cosmetic compositions providing improved skin protection and methods of cosmetic treatment using said compositions. Background technique [0002] Skin is the first line of defense that acts as a barrier between us and our environment. The skin is a complex organ consisting of three layers: epidermis, dermis and hypodermis. [0003] The epidermis is the outermost layer, which itself consists of multiple layers. The outermost part of the epidermis, called the stratum corneum, is relatively waterproof and prevents most bacteria, viruses, and other foreign substances from entering the body when undamaged. It also prevents the loss of water, heat and other vital components of the body. [0004] The majority of cells (90-95%) in the epidermis are keratinocytes. They arise from the proliferation of keratinocyte stem cells in the deepest layer of the epidermis called the basal layer. The resulting keratinocytes further div...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/41A61Q17/00A61Q17/04A61K8/9789A61K8/9794A61K8/9771A61P17/02
CPCA61K8/41A61Q17/00A61Q17/04A61K8/97A61K2800/522A61P17/02A61K8/68A61K8/9789
Inventor 利安娜·玛丽·詹姆斯克莱尔·海伦娜·奥康纳
Owner BOOTS PURE DRUG CO LTD