Applications of Amurensin H derivatives in preparation of drugs for treating liver related diseases

A technology of glupapentin and its derivatives, which is applied in the field of biomedicine and can solve the problems of few research reports
CN110433152AInactive Publication Date: 2019-11-12INST OF MATERIA MEDICA CHINESE ACAD OF MEDICAL SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF MATERIA MEDICA CHINESE ACAD OF MEDICAL SCI
Publication Date
2019-11-12
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses applications of Amurensin H derivatives shown as a formula (I), (II) and (III) and pharmaceutically acceptable salt thereof in the preparation of drugs for treating and / or preventing liver related diseases, and also discloses the preparation method of a compound, and applications of the pharmaceutical composition of the compound in the preparation of the drugs for treatingand / or preventing the liver related diseases.
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Description

technical field

[0001] The present invention relates to the field of biomedicine, in particular to a class of glupapentin derivatives or their medically acceptable salts, and the application of pharmaceutical compositions containing these derivatives in the preparation of drugs for treating and / or preventing liver-related diseases . Background technique

[0002] The development of new drugs based on active natural products is one of the important ways of modern drug development. Natural products have the characteristics of wide sources, low toxicity and few side effects. Discovering natural lead compounds with significant activity from traditional Chinese herbal medicines, through structural modification, combined with systematic in vivo and in vitro activity tests and comprehensive evaluation of druggability, to find safe and efficient candidate compounds as clinically useful prototype drugs, is the key to drug research and development. important direction. Oligomeric st...

Claims

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