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A traditional Chinese medicine composition for treating hypoxic kidney injury, preparation method and application thereof

A composition and kidney injury technology, applied in drug combinations, pharmaceutical formulations, urinary system diseases, etc., can solve problems such as the inability to fully fit the course and pathological characteristics of chronic renal failure diseases, and the difficulty of in-depth research on chronic renal failure diseases. The preparation method is simple, the effect is remarkable, and the curative effect is good

Active Publication Date: 2021-08-10
SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The deficiency of the existing animal models of chronic renal failure lies in that it fails to fully reflect the important pathological factors of ischemia-hypoxia in the kidney, and cannot fully fit the course and pathological characteristics of chronic renal failure disease progression, which brings certain benefits to the in-depth study of chronic renal failure. difficulty

Method used

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  • A traditional Chinese medicine composition for treating hypoxic kidney injury, preparation method and application thereof
  • A traditional Chinese medicine composition for treating hypoxic kidney injury, preparation method and application thereof
  • A traditional Chinese medicine composition for treating hypoxic kidney injury, preparation method and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Embodiment 1 Chinese medicine composition (one)

[0042] The raw materials are taken according to the following proportions by weight: 9 parts of Codonopsis pilosula, 9 parts of fairy spleen, 6 parts of aconite, 10 parts of salvia miltiorrhiza, 6 parts of rhubarb, 6 parts of perilla leaves, 9 parts of peach kernels, 4 parts of Cordyceps mycelium, 9 parts of raw Puhuang, 3 parts of Sun-cured Cimicifuga, and 9 parts of Wulingzhi.

Embodiment 2

[0043] Embodiment 2 Chinese medicine composition (two)

[0044] The raw materials are taken according to the following proportions by weight: 15 parts of Codonopsis pilosula, 15 parts of fairy spleen, 12 parts of Radix Aconite, 20 parts of Salvia miltiorrhiza, 12 parts of rhubarb, 12 parts of perilla leaves, 15 parts of peach kernels, 8 parts of Cordyceps mycelium, 15 parts of raw Puhuang, 12 parts of sun-cured cohosh, and 15 parts of Wulingzhi.

Embodiment 3

[0045] Embodiment 3 Chinese medicine composition (three)

[0046] The raw materials are taken according to the following proportions by weight: 9 parts of Codonopsis pilosula, 15 parts of fairy spleen, 6 parts of Radix Aconiti, 20 parts of Salvia miltiorrhiza, 6 parts of rhubarb, 12 parts of perilla leaves, 9 parts of peach kernels, 8 parts of Cordyceps mycelium, 9 parts of raw Puhuang, 12 parts of Sun-cured Cimicifuga, and 9 parts of Wulingzhi.

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Abstract

The invention relates to a traditional Chinese medicine composition for treating hypoxic kidney injury disease. The traditional Chinese medicine composition is made of the following raw materials in parts by weight: 12 parts of Codonopsis pilosula, 12 parts of Xianling spleen, 9 parts of Paofuzi, and 15 parts of Danshen , 9 parts of rhubarb, 9 parts of perilla leaves, 12 parts of peach kernels, 6 parts of Cordyceps mycelia, 12 parts of raw cattail, 9 parts of sun-cured cohosh, and 12 parts of Wulingzhi. The invention also includes the application of the traditional Chinese medicine composition in the preparation of medicine for treating hypoxic kidney injury. Its advantages are as follows: 1. The selected raw materials conform to the compatibility principle of "jun, minister, assistant and envoy", and have synergistic effects, and the curative effect is good, and the optimal ratio of each raw drug is obtained through experimental screening, which has the advantages of remarkable effect. 2. The preparation method of the medicine of the present invention is simple and convenient, and each raw material medicine has a wide range of sources. 3. The present invention provides a new treatment plan for patients suffering from hypoxic kidney injury diseases, improves the survival rate of such patients, and has a good application prospect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating hypoxic kidney injury, a preparation method and application thereof. Background technique [0002] Chronic renal failure (hereinafter referred to as chronic renal failure) is a clinical syndrome in which renal function slowly declines until failure on the basis of various chronic kidney diseases, and its main pathological changes are glomerular sclerosis and renal interstitial Fibrosis is the main pathological basis for the progression of chronic kidney disease of various causes to end-stage renal disease. According to the epidemiological survey in China, the prevalence of chronic renal failure is as high as 10.8%, and with the rising incidence of secondary kidney disease, the incidence of chronic renal failure is still rising, which has brought great harm to the family and society. heavy financial burd...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/88A61P13/12A61K35/24
CPCA61K35/24A61K36/068A61K36/296A61K36/344A61K36/535A61K36/537A61K36/708A61K36/71A61K36/714A61K36/736A61K36/88A61K2236/331A61K2236/39A61K2236/51A61K2236/55A61P13/12A61K2300/00
Inventor 王琛王蒙杨婧徐琳杨雪军叶朝阳
Owner SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M