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Traditional Chinese medicine composition for treating anoxic kidney injury disease and preparation method and application thereof

A composition and kidney injury technology, applied in drug combinations, pharmaceutical formulations, urinary system diseases, etc., can solve problems such as the inability to fully fit the course and pathological characteristics of chronic renal failure diseases, and the difficulty of in-depth research on chronic renal failure diseases. The preparation method is simple, the effect is remarkable, and the effect of good application prospect

Active Publication Date: 2019-11-15
SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The deficiency of the existing animal models of chronic renal failure lies in that it fails to fully reflect the important pathological factors of ischemia-hypoxia in the kidney, and cannot fully fit the course and pathological characteristics of chronic renal failure disease progression, which brings certain benefits to the in-depth study of chronic renal failure. difficulty

Method used

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  • Traditional Chinese medicine composition for treating anoxic kidney injury disease and preparation method and application thereof
  • Traditional Chinese medicine composition for treating anoxic kidney injury disease and preparation method and application thereof
  • Traditional Chinese medicine composition for treating anoxic kidney injury disease and preparation method and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Embodiment 1 Chinese medicine composition (one)

[0042] The raw materials are taken according to the following proportions by weight: 9 parts of Codonopsis pilosula, 9 parts of fairy spleen, 6 parts of aconite, 10 parts of salvia miltiorrhiza, 6 parts of rhubarb, 6 parts of perilla leaves, 9 parts of peach kernels, 4 parts of Cordyceps mycelium, 9 parts of raw Puhuang, 3 parts of Sun-cured Cimicifuga, and 9 parts of Wulingzhi.

Embodiment 2

[0043] Embodiment 2 Chinese medicine composition (two)

[0044] The raw materials are taken according to the following proportions by weight: 15 parts of Codonopsis pilosula, 15 parts of fairy spleen, 12 parts of Radix Aconite, 20 parts of Salvia miltiorrhiza, 12 parts of rhubarb, 12 parts of perilla leaves, 15 parts of peach kernels, 8 parts of Cordyceps mycelium, 15 parts of raw Puhuang, 12 parts of sun-cured cohosh, and 15 parts of Wulingzhi.

Embodiment 3

[0045] Embodiment 3 Chinese medicine composition (three)

[0046] The raw materials are taken according to the following proportions by weight: 9 parts of Codonopsis pilosula, 15 parts of fairy spleen, 6 parts of Radix Aconiti, 20 parts of Salvia miltiorrhiza, 6 parts of rhubarb, 12 parts of perilla leaves, 9 parts of peach kernels, 8 parts of Cordyceps mycelium, 9 parts of raw Puhuang, 12 parts of Sun-cured Cimicifuga, and 9 parts of Wulingzhi.

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Abstract

The invention relates to a traditional Chinese medicine composition for treating anoxic kidney injury disease. The traditional Chinese medicine composition is prepared from the following raw materialsin parts by weight: 12 parts of dangshen roots, 12 parts of epimedium, 9 parts of prepared common monkshood branched roots, 15 parts of danshen roots, 9 parts of prepared rhubarb roots, 9 parts of perilla leaves, 12 parts of peach kernels, 6 parts of cordyceps sinensis hypha, 12 parts of cattail pollen, 9 parts of roasted largetrifoliolious bugbane rhizomes and 12 parts of trogopterus dung. The invention also comprises application of the traditional Chinese medicine composition in preparing medicaments for treating anoxic kidney injury disease. The composition has the advantages that: 1, theselected raw materials conform to the compatibility principle of 'monarch, minister, assistant and guide', the synergistic effect is achieved, the curative effect is good, and the raw materials are screened through tests to obtain the optimal proportion, so that the composition has the advantage of obvious effect; 2, the medicine preparation method is simple and convenient, and the source of the raw material medicines is wide; and 3, the composition provides a new treatment scheme for patients suffering from anoxic renal injury disease, improves the survival rate of the patients, and has goodapplication prospect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating hypoxic kidney injury, a preparation method and application thereof. Background technique [0002] Chronic renal failure (hereinafter referred to as chronic renal failure) is a clinical syndrome in which renal function slowly declines until failure on the basis of various chronic kidney diseases, and its main pathological changes are glomerular sclerosis and renal interstitial Fibrosis is the main pathological basis for the progression of chronic kidney disease of various causes to end-stage renal disease. According to the epidemiological survey in China, the prevalence of chronic renal failure is as high as 10.8%, and with the rising incidence of secondary kidney disease, the incidence of chronic renal failure is still rising, which has brought great harm to the family and society. heavy financial burd...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P13/12A61K35/24
CPCA61K35/24A61K36/068A61K36/296A61K36/344A61K36/535A61K36/537A61K36/708A61K36/71A61K36/714A61K36/736A61K36/88A61K2236/331A61K2236/39A61K2236/51A61K2236/55A61P13/12A61K2300/00
Inventor 王琛王蒙杨婧徐琳杨雪军叶朝阳
Owner SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M