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A cross water maze for behavioral testing

A technology of water maze and cross, applied in the field of cross water maze, can solve the problems of uncombined equipment and single training method, and achieve the effect of improving spatial learning ability and exploration ability

Active Publication Date: 2021-10-19
NINGBO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, many literatures tend to agree that exercising more and thinking often can reduce the risk of dementia, but the existing equipment only reflects a single training method, such as treadmill and wheel exercise, which provide a sense of direction and purpose. Pure exercise mode, while water maze, Y maze and elevated cross maze provide a pure thinking activity mode, and there is no equipment that combines the two needs

Method used

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  • A cross water maze for behavioral testing
  • A cross water maze for behavioral testing
  • A cross water maze for behavioral testing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment one: if figure 1 with figure 2 As shown, a cross water maze for behavior testing includes a circular water tank 1, a cross maze 2 is fixedly arranged in the center of the water tank 1, the cross maze 2 is located above the water surface, and the cross maze 2 includes a first labyrinth with an open top surface Passage 3, the second labyrinth passage 4, the 3rd labyrinth passage 5 and the 4th labyrinth passage 6, the connecting end of the first labyrinth passage 3, the connecting end of the second labyrinth passage 4, the connecting end of the 3rd labyrinth passage 5 and the fourth The connection end of labyrinth passage 6 connects and surrounds central passage 7, and the free end of the first maze passage 3 is provided with entrance 8, and the second maze passage 4 is provided with the variable-speed treadmill 9 that stimulates animal movement, and on the 3rd maze passage 5, The fourth maze channel 6 and the central channel 7 are provided with electrical sti...

Embodiment 2

[0036] Embodiment 2: Other structures are the same as Embodiment 1, the difference is that the free end of the third labyrinth channel 5 is closed, and the first electric shock zone 51 includes a first copper sheet (not shown in the figure) and a first electric grid (not shown in the figure), the first copper sheet (not shown in the figure) is arranged on the inner walls of both sides of the third labyrinth channel 5, and the first electric grid (not shown in the figure) is laid on the middle bottom surface of the third labyrinth channel 5 Above, the first electric grid (not shown in the figure) is electrically connected to the second control switch 241, and the first copper sheet (not shown in the figure) is electrically connected to the first electric grid (not shown in the figure). Wherein, the first electric grid is an existing technology.

[0037] In this specific embodiment, the second electric shock zone 61 includes a second copper sheet (not shown in the figure) and a ...

Embodiment 3

[0038] Embodiment three, other structures are identical with embodiment two, and its difference is: the inner and outer walls of the first labyrinth passage 3 are marked with yellow, the inner and outer walls of the second labyrinth passage 4 are marked with green, and the inner and outer walls of the third labyrinth passage 5 are marked with green. Marked in red, the inner and outer walls of the fourth labyrinth passage 6 are marked in blue.

[0039] In this specific embodiment, a thermostatic controller (not shown in the figure) is arranged in the water tank 1, and the thermostatic controller is changed to the prior art.

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Abstract

The invention discloses a cross water maze for behavior testing. The cross maze includes a first labyrinth channel, a second labyrinth channel, a third labyrinth channel and a fourth labyrinth channel, a connecting end of the first labyrinth channel and a connecting end of the second labyrinth channel , the connecting end of the third labyrinth channel and the connecting end of the fourth labyrinth channel are connected to form a central channel, the free end of the first labyrinth channel is provided with an entrance, the second labyrinth channel is provided with a variable-speed treadmill to stimulate animal movement, and the third labyrinth channel Electrical stimulation units are arranged on the upper, fourth and central passages of the maze, and the free end of the fourth maze passage is provided with an exit, and a lift-type target platform for animals to stand on one foot is also set in the water tank, and the lift-type target platform is close to the entrance Its advantage is not only to ensure the amount of exercise of experimental animals, but also to ensure that the movement has a sense of position and direction, which is conducive to research and application in the fields of senile dementia, intelligence and aging, new drug development / screening / evaluation, learning and memory, and preventive medicine.

Description

technical field [0001] The invention relates to a behavior testing device for animal learning ability, in particular to a cross water maze for behavior testing. Background technique [0002] The Morris water maze has a circular tank with a diameter of 1.2m and a target platform with a diameter of 10cm. It uses the motivation of experimental animals to escape from the water environment, forces them to swim, and learns to find hidden platforms in the water. It is mainly used for testing experimental animals. The ability to learn and remember the sense of spatial position and direction (spatial orientation) is the classic experiment of choice for learning and memory research. The Y maze is divided into electrical stimulation type and food reward type. It consists of three identical arms and a connection area. The angle between the three arms is 120°. According to the escape response or feeding drive of experimental animals after electric shock, the number and time of animals e...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01K15/02
CPCA01K15/02A01K15/027
Inventor 李丽萍王钦文刘志涛李婉怡王福艳苗苗裘艺莎朱依依常岚
Owner NINGBO UNIV
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