Composition with effect of preventing and treating complications of dialysis patient, and preparation method and application of composition

Abstract

The invention provides a composition with the effect of preventing and treating complications of a dialysis patient, and a preparation method and application of the composition. The composition is prepared from the components in parts by mass: 5-33 parts of whey proteins, 1-20 parts of casein or salts of the casein, 1-50 parts of maltodextrin, 1-10 parts of corn syrup and 5-75 parts of sunflower seed oil. The blood potassium level can be controlled to be lower than 5.0 mmol / L, the blood phosphorus level is controlled to be lower than 1.78 mmol / L, the complications such as protein malnutrition,hyperphosphatemia, hyperkalemia and hypertension of the dialysis patient are comprehensively relieved, the dialysis interval time of the dialysis patient is prolonged, and the harm of dialysis to thebody is reduced. In addition, the composition in each unit dose is brewed with 60 mL of water, the liquid intake burden is relieved and is equivalent to the osmotic pressure of the human body, gastrointestinal tolerance is better, and patient compliance is higher.

Description

technical field [0001] The invention belongs to the field of biomedicine, and in particular relates to a composition capable of preventing and treating complications of dialysis patients, a preparation method thereof and an application thereof. Background technique [0002] Dialysis therapy uses hemodialysis and / or peritoneal dialysis to excrete components (such as solutes or water, etc.) in the body fluid of the dialysis patient through a semipermeable membrane. Hemodialysis uses the principle of semi-permeable membranes to expel various harmful metabolites and excess electrolytes from the body through diffusion, purify the patient's blood, correct water, electrolyte and acid-base balance, etc. Peritoneal dialysis uses the peritoneum as a semi-permeable membrane, uses gravity to pour the prepared dialysate into the patient's peritoneal cavity through the catheter, and then constantly replaces the peritoneal dialysate to remove metabolites and toxic substances in the body an...

AI Technical Summary

Problems solved by technology

[0008] 5. Anemia

But there are following defects: the one, chestnut powder has increased the complexity of preparation technology and production cost; Complications of blood potassium; third, the composition and proportion of nutrients do not meet the requirements of guidelines for kidney disease, making it difficult to comprehensively improve protein energy deficiency, hyperphosphatemia, hyperkalemia, renal hypertension, and postdialysis hypotension in dialysis patients , anemia and other complications

[0017] In summary, the nutritional protein powder disclosed in the prior art for patients with kidney disease and dialysis has many defects: (1) The product mostly uses soybean protein as a raw material, and lacks the high purity, reasonable amino acid composition, high absorption, and high growth rate of whey protein concentrate. (2) Most of the products contain fructooligosaccharides, inulin, chestnut powder, etc., and the protein and energy composition ratio of the composition is difficult to meet the clinical needs of dialysis patients. Its comprehensive effect on improving the complications of dialysis patients is not good; (3) frequent use increases the treatment cost of patients and increases the burden of medical insurance, and the patient consumes a large amount of water, which increases the burden on the kidneys of patients with kidney disease and increases the risk of severe kidney disease

(4) Existing products or methods for improving complications of renal dialysis patients mostly use drugs or nutritional supplements to improve a certain complication of dialysis patients, and their comprehensive effect on improving dialysis complications is very limited

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