Nano-micelle with in-situ hydrogen production function and preparation method and application thereof
A nanomicelle, in-situ technology, applied in the field of nanomedical materials, can solve the problems of limited application, volatile hydrogen molecules, and difficult to store stably, and achieve the effect of inhibiting tumor growth.
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[0028] The present invention provides a nanomicelle with in-situ hydrogen production and its preparation method and application. In order to make the purpose, technical scheme and effect of the present invention clearer and clearer, the present invention will be further described in detail below. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.
[0029] An embodiment of the present invention provides a nanomicelle with in situ hydrogen generation, wherein the nanomicelle includes: fluorinated chitosan, [FeFe] hydrogenase and chemotherapeutic drugs, and the [FeFe] hydrogenase and chemotherapeutic The drug is loaded in the inner core of the nano-micelle, and the fluorinated chitosan constitutes the outer shell of the nano-micelle.
[0030] This example provides a nanomicelle with in-situ hydrogen production, which is composed of a fluorinated chitosan polymer with cell membran...
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