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Preparation method of medicine mixer

A drug mixer and mixture technology, which is applied in heating and other directions, can solve the problems of drug dissolution, easy blockage of blood vessels, granulation, etc., and achieve the effects of long service life, high comfort and high safety

Inactive Publication Date: 2020-02-21
HUNAN NOVOL MEDICINE CHARTERS MATERIAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to overcome the existence of traditional powder injection infusion dispensing. During the dispensing, it is necessary to dissolve the medicine, oscillate and mix it, and repeatedly extract the medicine liquid. During this process, repeated punctures are likely to produce rubber plug particles, and the rubber plug particles enter the human body. It is easy to block blood vessels, produce granulation, inflammation and other problems

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Step 1 of a preparation method of a drug mixer: mixing pp raw materials and additives to form a uniform mixture;

[0022] Step 2: Feed the mixture into the twin-screw extruder at a temperature of 190-230°C, and then extrude the strands;

[0023] Step 3: Put the strands into the water cooling box for water cooling, and cool the temperature of the strands to 40-60°C, so that the strands have both toughness and brittleness, which facilitates the pelletizing of the strands;

[0024] Step 4: Pelletize the cooled strands, blow dry them, and inject the obtained materials according to the shape of the product.

[0025] Preferably, the PP raw material in the step 1 is composed of polypropylene, ethylene-hexene-propylene copolymer, styrene-ethylene-butylene-styrene copolymer and ethylene-propylene copolymer, and the polypropylene The weight ratio is 45% to 75%; the weight ratio of the ethylene-hexene-propylene copolymer is 5% to 15%; the weight ratio of the styrene-ethylene-buty...

Embodiment 2

[0027] Step 1 of a preparation method of a drug mixer: mixing pp raw materials and additives to form a uniform mixture;

[0028] Step 2: Feed the mixture into the twin-screw extruder at a temperature of 190-230°C, and then extrude the strands;

[0029] Step 3: Put the strands into the water cooling box for water cooling, and cool the temperature of the strands to 40-60°C, so that the strands have both toughness and brittleness, which facilitates the pelletizing of the strands;

[0030] Step 4: Pelletize the cooled strands, blow dry them, and inject the obtained materials according to the shape of the product.

[0031] Preferably, the additive is composed of an antioxidant and an acid scavenger, and the antioxidant includes pentaerythritol tetraphenylpropionate and triphosphite; the acid scavenger is hydrotalcite; The additive does not exceed 0.3% of the total weight of the mixture.

Embodiment 3

[0033] Step 1 of a preparation method of a drug mixer: mixing pp raw materials and additives to form a uniform mixture;

[0034] Step 2: Feed the mixture into the twin-screw extruder at a temperature of 190-230°C, and then extrude the strands;

[0035] Step 3: Put the strands into the water cooling box for water cooling, and cool the temperature of the strands to 40-60°C, so that the strands have both toughness and brittleness, which facilitates the pelletizing of the strands;

[0036] Step 4: Pelletize the cooled strands, blow dry them, and inject the obtained materials according to the shape of the product.

[0037] Preferably, the step 4 is sterilized at a temperature of 121° C. after injection molding, so that the product does not deform and discolor, has high strength and long service life.

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PUM

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Abstract

The invention provides a preparation method of a medicine mixer, and belongs to preparation methods of medical products. According to the preparation method of the medicine mixer, the temperature of abrace is cooled to 40-60 DEG C, so that the brace has not only certain toughness but also certain brittleness, and the brace is conveniently cut into grains; PP raw material consists of polypropylene, an ethylene-hexene-propylene copolymer, a styrene-ethylene-butene-styrene copolymer and an ethylene-propylene copolymer; nonvolatile matter per 100 ml is dissolved out by 0.49 mg in a dissolution test, and the safety is high; the puncture force value is less than 40 N in a use adaptability test, the puncture permeability performance is excellent, and no chip falls during puncture, so that the problems that rubber plug particles enter a human body to block blood vessels and generate granulation and inflammation are effectively avoided; and after injection molding, sterilization is carried outwith the temperature of 121 DEG C, so that the medicine mixer is not deformed, does not change color, and has high strength and long service life.

Description

technical field [0001] The invention belongs to a preparation method of a medical product, in particular to a preparation method of a medicine mixer. Background technique [0002] A drug mixer is a device for mixing powders and injections before injecting drugs to patients. [0003] However, the traditional powder injection infusion dispensing still exists. During the dispensing, it is necessary to dissolve the medicine, oscillate and mix it, and repeatedly extract the medicine solution. During this process, repeated punctures are likely to produce rubber plug particles. When rubber plug particles enter the human body, they are likely to block blood vessels and produce granulation. , inflammation and other issues. Contents of the invention [0004] The purpose of the present invention is to overcome the existence of traditional powder injection infusion dispensing. During the dispensing, it is necessary to dissolve the medicine, oscillate and mix it, and repeatedly extrac...

Claims

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Application Information

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IPC IPC(8): B29B9/06B29B9/16B29C48/40B29C48/92B29C48/88B29C45/00A61L2/04C08L23/12C08L23/08C08L53/02
CPCA61L2/04B29B9/065B29B9/16B29C45/0001B29C48/40B29C48/88B29C48/92B29C2948/92704C08L23/12C08L2205/025C08L2205/035C08L23/0815C08L53/025
Inventor 夏岳韬何小平
Owner HUNAN NOVOL MEDICINE CHARTERS MATERIAL SCI TECH
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