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Non-contact micro/nano-particle control method

A non-contact and granular technology, applied in the direction of liquid separation into beads and granulation, etc., can solve the problems of cell damage, liquid volume reduction, detachment, etc., and achieve the effect of easy miniaturization, good convenience, and good reliability

Active Publication Date: 2020-04-07
HUAIYIN INSTITUTE OF TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantage of this method of gathering micro / nano substances is that the vibration transmission needle and the ring are in direct contact with the suspension, which will pollute the micro / nano substances, and ultrasonic waves are prone to occur at the gas-liquid-solid three-phase interface. Atomization, so that the volume of the liquid is continuously reduced and a part of the micro / nano substances are separated from the suspension with the atomized micro-droplets
In biomedicine, in order to control the movement of micro / nano substances in cells or organic solutions, precision tweezers are often used, which can easily cause irreversible damage to cells and other organisms.

Method used

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  • Non-contact micro/nano-particle control method

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Embodiment Construction

[0023] The present invention will be described in detail below in conjunction with the accompanying drawings.

[0024] In the description of the invention, it should be understood that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "vertical", "horizontal", "top", "bottom" etc. The orientation or positional relationship shown in the figure is only for the convenience of describing the present invention and simplifying the description, and does not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be construed as a reference to this invention. Invention Limitations.

[0025] In the present invention, unless otherwise clearly specified and limited, terms such as "installation", "connection", "connection" and "fixation" should be understood in a broad sense, for example, it can be a fixed connection or a detachable connec...

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Abstract

The invention relates to the technical field of ultrasonic and micro-nano control, and discloses a non-contact micro / nano-particle control method. A device for implementing the method comprises an ultrasonic transducer, a vibration transmission plate, a substrate and a plurality of ultrasonic needles. The method comprises the following steps: S1, mixing a solution with micro / nano particles; S2, dropwise adding the mixed solution obtained in step S1 onto the substrate to form liquid drops; S3, adjusting distances between the liquid drops in step S2 and the ultrasonic needles to make the liquiddrops not in contact with the ultrasonic needles; S4, starting the ultrasonic transducer, and adjusting the working frequency and the working voltage of the ultrasonic transducer; and S5, adjusting direction angles between the ultrasonic needles and the liquid drops to realize micro / nano-particle control. Non-contact control avoids damage and pollution to micro / nano particles in the prior art, andthe device has the advantages of easiness in miniaturization, convenience in use, good reliability and the like.

Description

technical field [0001] The present invention relates to the technical field of ultrasonic and micro-nano control, in particular to a nonlinear acoustic vortex generated in liquid droplets by ultrasonic excitation to perform non-contact rotation, aggregation, and removal of micro / nano particles in liquid droplets. Methods. Background technique [0002] With the rapid development of scientific fields such as biomedicine and micro-nano manufacturing, how to realize the controllable manipulation of micro / nano particles in laboratory and industrial production has become an important direction of scientific research. Manipulation of micro / nanoparticles in the way of pollution is a major technical issue we are facing. Existing micro / nano manipulation methods include optical tweezers, dielectrophoresis, magnetophoresis, etc., but these manipulation methods not only require the photoelectromagnetic properties of micro / nano particles, but may also cause irreversible damage to the man...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01J2/02
CPCB01J2/02
Inventor 汤强汪通悦沈旺陈校
Owner HUAIYIN INSTITUTE OF TECHNOLOGY
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