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Rapid film-forming liquid bandage containing pseudo-ginseng extracting solution

A technology of extracting liquid and band-aid, applied in the field of medical supplies, can solve the problems of complex preparation process of liquid band-aid, poor film-forming performance of film-forming materials, and few types of film-forming materials, etc., so as to shorten the plasma recalcification time and reduce the plasma recalcification time. The effect of shortening the time and shortening the film formation time

Active Publication Date: 2020-04-10
中山大学新华学院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main problems in the current research on liquid band-aids are that the preparation process of liquid band-aids is complicated, there are few types of film-forming materials, and the film-forming properties of film-forming materials are not good [Liu Haixia, Zhang Aijun, Zhang Lin. Research progress on liquid band-aids[J] .Chinese Medical Science, 2016,6(4):28-31]
Patent CN105363066A discloses a liquid band-aid made of PVB, PVP, ethanol, ethyl acetate, and glycerin, but the film-forming time of the obtained liquid band-aid is 2 to 3 minutes, and the film-forming time is too long, which is not conducive to the hemostasis of the wound

Method used

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  • Rapid film-forming liquid bandage containing pseudo-ginseng extracting solution
  • Rapid film-forming liquid bandage containing pseudo-ginseng extracting solution
  • Rapid film-forming liquid bandage containing pseudo-ginseng extracting solution

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Embodiment 1 Preparation and performance evaluation of a liquid band-aid

[0037] 1. Preparation of liquid band-aid

[0038] (1) Preparation of Radix Notoginseng Extract

[0039] Weigh 30g of Panax notoginseng powder, put it in a conical flask, add 500mL of pure water, ultrasonically extract twice, each time for 15min, 3500r·min -1 Centrifuge for 15 minutes, take the supernatant to obtain the Panax notoginseng water, transfer it to a conical flask, concentrate the water extract at 80°C to 50 mL, and obtain the Panax notoginseng extract.

[0040] (2) Preparation of Liquid Band-Aids Added with Panax notoginseng Extract

[0041] S1. Weigh 25g of ethanol, 23g of butyl acetate and 26g of amyl acetate and mix evenly, weigh 8g of PVB-180S while stirring, add the mixed solution, seal (to prevent volatilization) and stir until dissolved;

[0042] S2. Add 0.5g of PVA to continue to dissolve completely, add 0.5g of castor oil and mix well;

[0043] S3. Add 1 g of Panax notogin...

Embodiment 2

[0063] Embodiment 2 Preparation and performance evaluation of a liquid band-aid

[0064] 1. Preparation of liquid band-aid

[0065] (1) Preparation of Radix Notoginseng Extract

[0066] Weigh 30g of Panax notoginseng powder, put it in a conical flask, add 500mL of pure water, ultrasonically extract twice, each time for 15min, 3500r·min -1 Centrifuge for 15 minutes, take the supernatant to obtain the Panax notoginseng water, transfer it to a conical flask, concentrate the water extract at 80°C to 50 mL, and obtain the Panax notoginseng extract.

[0067] (2) Preparation of Liquid Band-Aids Added with Panax notoginseng Extract

[0068] S1. Weigh 24g of ethanol, 25g of butyl acetate and 28g of amyl acetate and mix evenly, weigh 10g of PVB-180S and add the mixture while stirring, seal it (to prevent volatilization) and stir until dissolved;

[0069] S2. Add 1.5g of PVA to continue to dissolve completely, add 1.0g of castor oil and mix well;

[0070] S3. Add 2g of Panax notogins...

Embodiment 3

[0083] Embodiment 3 A kind of preparation of liquid band-aid and its performance evaluation

[0084] 1. Preparation of liquid band-aid

[0085] (1) Preparation of Radix Notoginseng Extract

[0086] Weigh 30g of Panax notoginseng powder, put it in a conical flask, add 500mL of pure water, ultrasonically extract twice, each time for 15min, 3500r·min -1 Centrifuge for 15 minutes, take the supernatant to obtain the Panax notoginseng water, transfer it to a conical flask, concentrate the water extract at 80°C to 50 mL, and obtain the Panax notoginseng extract.

[0087] (2) Preparation of Liquid Band-Aids Added with Panax notoginseng Extract

[0088] S1. Weigh 23g of ethanol, 21g of butyl acetate and 24g of amyl acetate and mix evenly, weigh 6g of PVB-180S while stirring, add the mixed solution, seal (to prevent volatilization) and stir until dissolved;

[0089] S2. Add 0.5g of PVA to continue dissolving completely, add 0.5g of castor oil and mix well;

[0090] S3. Add 1 g of Pa...

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Abstract

The invention discloses a rapid film-forming liquid bandage containing a pseudo-ginseng extracting solution. Experiments show that when the pseudo-ginseng extracting solution is added into the formulaof the liquid bandage, the film-forming property can be remarkably improved, the film-forming time is greatly shortened, and meanwhile, the plasma recalcification time is also greatly shortened. Theliquid bandage is prepared by mixing PVB-180S, PVA, castor oil, amyl acetate, butyl acetate, ethanol, peppermint oil and the pseudo-ginseng extracting solution. According to the invention, the film-forming materials are reasonably compounded; by adding the pseudo-ginseng extracting solution, the prepared liquid bandage can greatly shorten the plasma recalcification time and promote wound hemostasis, and the prepared liquid bandage can be rapidly diffused, rapidly dried and formed into a breathable and waterproof elastic protective film, so that the wound surface is instantly sealed, and woundinfection and bacterial invasion are prevented.

Description

technical field [0001] The invention relates to the technical field of medical supplies, in particular to a rapid film-forming liquid band-aid containing a panax notoginseng extract. Background technique [0002] Band-aid is the most commonly used surgical drug in people's life. The traditional band-aid is a long adhesive plaster with gauze soaked in medicine in the middle, so as to protect the wound and temporarily stop bleeding. Traditional band-aids are suitable for superficial wounds, neat and clean wounds, little bleeding and small wounds that do not require sutures. Compared with traditional band-aids, liquid band-aids are not only more effective, waterproof, and more breathable, but also have no shape restrictions on the wound, just apply directly to the wound, non-greasy, non-stick to clothing, free movement, clean and dry. The liquid band-aid is easy to use, has a wide range of applications, and has great development value. [0003] Liquid bandage (1liquid bandage...

Claims

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Application Information

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IPC IPC(8): A61L26/00
CPCA61L26/0057A61L26/0061A61L26/0066A61L2300/30A61L2300/418A61L2400/04
Inventor 徐娟娟张素中王有娣郑晖晖何杺虞
Owner 中山大学新华学院
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