Nose comforting tablet and preparation method and use method thereof

A comfortable tablet and comfortable technology, which is applied in the field of rhinitis medicine, can solve the problems of uneven quality of nasal comfort tablets, and achieve the effects of reducing oral drug dosage, improving curative effect, and improving solubility and volatility

Inactive Publication Date: 2020-06-19
广东省惠州市中药厂有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, there are currently many manufacturers and production processes for nasal comfort tablets, resulting in uneven quality of nasal comfort tablets. In addition, there are more and more air pollution harmful to human body in the current

Method used

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  • Nose comforting tablet and preparation method and use method thereof
  • Nose comforting tablet and preparation method and use method thereof
  • Nose comforting tablet and preparation method and use method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0033] One embodiment, a nasal comfort tablet, comprising the following traditional Chinese medicine components in parts by mass: 300-400 parts of cocklebur, 120-160 parts of wild chrysanthemum, 200-220 parts of geese not eating grass, 100-120 parts of Angelica dahurica, Fangfeng 100-120 parts, 200-220 parts of Eclipta, 130-160 parts of Paeoniae Alba, 60-80 parts of Dannanxing, 65-85 parts of licorice, 200-220 parts of Tribulus terrestris, and 0.1-0.5 parts of chlorpheniramine. The nasal comfort tablet prepared by the formula has the effects of clearing away heat, reducing inflammation and clearing the mind, and can be used for treating sneezing, runny nose, nasal congestion, headache, allergic rhinitis and chronic sinusitis caused by chronic rhinitis.

[0034] In order to improve the efficacy and quality of the Nasal Comfort Tablet, as another example, the Nasal Comfort Tablet includes the following traditional Chinese medicine components in parts by mass: 364 parts of cockleb...

Embodiment 1

[0055] The preparation method of nasal comfort tablet comprises the following steps: 364g cocklebur, 145g wild chrysanthemum, 218g goose not eating grass, 109g angelica, 109g Fangfeng, 218g black lotus, 145g white peony root, 70g dannanxing, 73g licorice, 218g Tribulus terrestris and 0.3 g of chlorpheniramine were mixed, followed by crushing operation, granulation operation and tabletting operation to obtain nasal comfort tablet.

[0056] The weight of each Nasal Comfort Tablet is 0.2g, orally 3 times a day, 2-3 tablets at a time, and fumigated for external use 2 times a day, 2-3 tablets at a time.

[0057] The method for fumigation of nasal comfort tablets for external use includes the following steps: putting the above-mentioned nasal comfort tablets and water into the medicine storage cavity 3111, covering the sealing cover 331, and controlling the stirring column 332 to stir, so that the The nasal comfort tablet is dissolved to obtain a medicinal liquid; the heating device...

Embodiment 2

[0060] The preparation method of nasal comfort tablet comprises the following steps: 364g cocklebur, 145g wild chrysanthemum, 218g goose not eating grass, 109g angelica, 109g Fangfeng, 218g black lotus, 145g white peony root, 70g dannanxing, 73g licorice, 218g Tribulus terrestris and 0.3g chlorpheniramine are mixed, and carbon dioxide supercritical extraction operation is carried out to obtain a pre-extraction; wherein, the extraction pressure is 30Mpa, the extraction temperature is 30°C, the separator pressure is 20Mpa, and the separator The temperature is 50°C, the separation time is 3h, and the carbon dioxide flow rate is 30L / h; the pre-extraction liquid is subjected to a decompression drying operation to obtain a pre-dry paste; wherein, the decompression drying operation temperature is 70 ℃; carry out high-energy nano-impact milling operation on the pre-dried paste to obtain pre-dried paste powder; wherein, the particle size of the pre-dried paste powder is 250nm; perform g...

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Abstract

The present invention relates to the field of rhinitis medicines and discloses a nasal comforting tablet and a preparation method and a use method thereof. The nasal comforting tablet comprises the following traditional Chinese medicine components in parts by mass: 300-400 parts of cocklebur fruits, 120-160 parts of wild chrysanthemum flowers, 200-220 parts of centipeda minima, 100-120 parts of radix angelicae, 100-120 parts of divaricate saposhnikovia root, 200-220 parts of herba ecliptae, 130-160 parts of white paeony root, 60-80 parts of arisaema cum bile, 65-85 parts of liquorice, 200-220parts of tribulus terrester and 0.1-0.5 part of chlorpheniramine. The formula of the nasal comforting tablet has effects of clearing heat, eliminating inflammation and freeing orifice, and can be usedto treat sneezing, runny nose, stuffy nose, headache, allergic rhinitis and chronic sinusitis caused by chronic rhinitis. Then special steps such as carbon dioxide supercritical extraction operationsand reduced-pressure drying operations can solve problems of slow disintegration of oral administration and insufficient volatilization of fumigation for external use; and then the oral administration and special fumigation for external use are combined to significantly improve curative effects of the nasal comforting tablet and reduce burden and side effects of oral administration drugs on humanbody liver.

Description

technical field [0001] The invention relates to the field of rhinitis drugs, in particular to a nasal comfort tablet and a preparation method and application method thereof. Background technique [0002] According to reports, one sixth of the world's population suffers from various types of rhinitis, and the incidence of rhinitis in China is much higher than this data. The rate of increase is 3-5%, while in China, because of environmental issues, this figure is about 10%. In 2015, the overall size of the ENT drug market was 13.9 billion yuan, an increase of 9% compared with 2014; from the perspective of ENT drug sales channels, the retail market is the largest sales channel in the ENT drug market, according to the monitoring data of Zhongkang CMH In 2015, the market share of otolaryngology drugs in retail pharmacies reached 52.5%; the share of urban level hospitals accounted for 26.7%. Judging from the changes in market share in the past two years, the growth momentum of r...

Claims

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Application Information

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IPC IPC(8): A61K36/8884A61K9/20A61P11/02A61P25/00A61P37/08A61K31/4402
CPCA61K9/0043A61K9/20A61K31/4402A61K36/185A61K36/232A61K36/238A61K36/28A61K36/287A61K36/484A61K36/65A61K36/71A61K36/8884A61K2236/37A61K2236/51A61P11/02A61P25/00A61P37/08A61K2300/00
Inventor 李玉英李六平余松铭
Owner 广东省惠州市中药厂有限公司
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