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Use of ulinastatin in preparing medicines for treating new coronavirus pneumonia

A technology of ulinastatin and coronavirus, applied in the field of medicine, can solve problems such as recovery of yang, and achieve the effect of rapid treatment, great social significance, and strong pertinence

Inactive Publication Date: 2020-06-26
GUANGDONG TECHPOOL BIO-PHARMA CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] As far as the current clinical manifestations of new coronary pneumonia are concerned, although the clinical manifestations of pneumonia caused by the new coronavirus have certain standards, compared with patients with SARS virus, there is a risk of returning to positive after cure, and in the presence of asymptomatic infections, the virus brings Very confusing, which brings great challenges to clinical treatment

Method used

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  • Use of ulinastatin in preparing medicines for treating new coronavirus pneumonia
  • Use of ulinastatin in preparing medicines for treating new coronavirus pneumonia
  • Use of ulinastatin in preparing medicines for treating new coronavirus pneumonia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1, preparation ulinastatin freeze-dried powder injection

[0021] Take 100 million units of ulinastatin after filtration sterilization, add 20g mannitol and 10g sodium chloride to dissolve, adjust the pH to 6.8, make up the volume to 1500mL with water for injection, filter aseptically, and distribute it in 1000 vials, Freeze-dried under sterile conditions, that is.

Embodiment 2

[0022] Embodiment 2, preparation ulinastatin freeze-dried powder injection

[0023] Take 100 million units of ulinastatin after filter sterilization, add 20g glucose and 5g sodium chloride to dissolve, adjust the pH to 7.1, make up the volume with water for injection to 1500mL, filter aseptically, and distribute it in 1000 vials, Freeze-dried under sterile conditions, that is.

Embodiment 3

[0024] Embodiment 3, preparation ulinastatin injection

[0025] Take 100 million units of ulinastatin after filter sterilization, add 20g mannitol and 10g sodium chloride to dissolve, adjust the pH to 6.9, make up the volume to 1500mL with water for injection, filter aseptically, and distribute it in 1000 vials, Instantly.

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Abstract

The present invention belongs to the technical field of medicine and particularly relates to a use of ulinastatin in preparing medicines for treating new coronavirus pneumonia. The present invention provides the use of the ulinastatin in preparing the medicines for treating the new coronavirus pneumonia. Clinical trials find that the ulinastatin has a significant therapeutic effect on the new coronavirus pneumonia.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to the use of ulinastatin in the preparation of drugs for the treatment of novel coronavirus pneumonia. Background technique [0002] At the end of December 2019, multiple cases of novel coronavirus pneumonia were discovered, and the World Health Organization officially named the disease "COVID-19". The novel coronavirus SARS-CoV-2 belongs to the genus β coronavirus, has an envelope, and the particles are round or oval, often pleomorphic, with a diameter of 60-140nm. According to the "Diagnosis and Treatment Plan for Novel Coronavirus Pneumonia (Trial Seventh Edition)" issued by the National Health and Health Commission, the clinical types of COVID-19 are mild, common, severe, and critical. Pneumonia manifests as mild; with fever, respiratory symptoms and other symptoms, imaging shows normal pneumonia; as for severe, adults meet any of the following as severe patients:...

Claims

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Application Information

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IPC IPC(8): A61K38/57A61P31/14A61P11/00
CPCA61K38/57A61P31/14A61P11/00
Inventor 宋建东张志军柯樱李翰明何少灵叶晓春祝琳
Owner GUANGDONG TECHPOOL BIO-PHARMA CO LTD
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