Artificial cornea

Abstract

The invention relates to an artificial cornea, and in particular relates to the artificial cornea that does not easily fall out, prevents the leakage of aqueous humor, and is beautiful and natural. The artificial cornea includes a central optical part and an umbrella wing is proposed, the central optical part is a round light-transmitting part, and the side surface is rough; the edge of the central optical part includes at least two fixing feet, and the fixing feet are used to be inserted into a corneal stroma of a graft bed to fix the central optical part and prevent the central optical partfrom falling out; the center of the umbrella-shaped wing is a circular hole and is arranged relative to the circular light-transmitting part, and the diameter of the central circular hole of the umbrella-shaped wing is less than or equal to the diameter of the circular light-transmitting part; the outer side of the central circular hole of the umbrella-shaped wing is an annular leak-proof zone; and the outer side of the umbrella-shaped wing annular leak-proof zone includes at least two side wings, and each side wing includes a biointegration zone for biointegration with a conjunctiva.

Description

technical field [0001] The invention relates to an artificial cornea, in particular to an artificial cornea which is not easy to prolapse, prevents the leakage of aqueous humor, and is beautiful and natural. Background technique [0002] Corneal transplantation technology is relatively mature, but the donor cornea is far from meeting the needs of a large number of patients with corneal diseases. In addition, the patient may have a rejection of the donor cornea and induce other eye diseases. Therefore, artificial corneas provide a new option for the treatment of patients. [0003] The teaching hospital of Harvard Medical School and the Department of Ophthalmology and Otology of Massachusetts General Hospital jointly publish the webpage of the Digital Journal of Ophthalmology http: / / www.djo.harvard.edu / site.php?idjo. The article "TheBoston Keratoprosthesis: A New Threadless Design" published at url= / physicians / oa / 1055 introduces a collar-buttoned corneal prosthesis Boston ty...

AI Technical Summary

Problems solved by technology

The paper "AlphaCor Artificial Cornea Transplantation Treating Rabbit Corneal Alkaline Burn" in the journal "Ophthalmology Research" in June 2010, Volume 28, Issue 6, explained that the postoperative complications of AlphaCor artificial cornea mainly include: (1) implantation of AlphaCor artificial cornea must be carried out Two operations before and after are not convenient enough for patients; (2) only relying on the centripetal tension formed by the artificial corneal skirt with a width of less than 1.5mm clamped and fixed by the front and rear lamellar corneas of the recipient, it is difficult to resist the impact of intraocular pressure on the artificial cornea. The external thrust of the cornea, so that the artificial cornea is easy to protrude; (3) PHEMA material may affect the transparency of the central optic part due to material precipitation and self-calcification tendency; (4) The plane of the central optic part is lower than its surroundings after the second stage operation The front lamellar plane of the cornea makes the exposed central optical area more prone to secretion adhesion and prelamellar graft fiber proliferation, which affects the patient's vision; (5) The overall diameter of the AlphaCor artificial cornea is 7.00 mm (mm), located in the center of the implant bed , accounting for only 1 / 2 of the entire recipient cornea area, and its peripheral skirt is opaque, in contrast, it is obviously different from the normal cornea, unsightly and natural

The shortcomings of the CorNeat artificial cornea are: (1) The posterior turret design used to prevent the protruding of the artificial cornea is actually a contact connection between the artificial cornea and the recipient cornea rather than a tight connection. The artificial cornea is affected by the eyelid. The impact of movement is prone to rotational displacement, and the posterior surface of the recipient cornea that the posterior castellation contacts is susceptible to abrasion by the posterior castellation, resulting in edema and melting of the implant bed

(2) The nano-pores of the integrated skirt are very small. It takes a long time for biological integration of such pores that can only be seen under an optical or even electron microscope, and the integrated tissue is not strong enough to effectively fix the CorNeat artificial cornea. (3) The connecting surface between the central optical part and the recipient cornea is smooth, and it is easy to move due to eye movement, and the recipient cornea is easily eroded, so the gap between the two increases, followed by leakage of aqueous humor

(4) Although the edge of the central optical part is marked for the incision of the inner eye surgery in the future, because the integrated skirt is designed in a dome shape, if other inner eye surgery is performed after artificial corneal implantation, the incision must go through Integrate the skirt cut, which inevitably destroys the adhesions between the cornea and the sclera, which are not dense

[0007] At present, the above-mentioned kinds of artificial corneas cannot meet the ideal requirements, and there are complications such as easy prolapse, aqueous humor leakage, too small size of the optical part, and unsightly appearance, respectively or at the same time.

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