Composition with multi-target acne removing effect and preparation method and application of composition
A composition and multi-target technology, applied in the directions of medical preparations containing active ingredients, drug combinations, preparations for skin care, etc., to achieve the effects of simple preparation process, good inhibition effect, and inhibition of acne inflammation
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Embodiment 1
[0036] This example provides a traditional Chinese medicine extract with multi-target anti-acne effect and its preparation method:
[0037] (1) Sophora flavescens extract, its preparation method: dry Sophora flavescens to constant weight, pulverize, pass through a 60-mesh sieve, and use 80% ethanol solution to reflux extract for 1 hour according to the ratio of solid to liquid (g:mL) , stirring continuously, filtering after the first extraction, and extracting the residue once with 80% ethanol, filtering, merging the filtrate twice, rotating the filtrate to concentrate into an extract, and freeze-drying to obtain the Sophora flavescens extract ;
[0038] Artemisia argyi extract, its preparation method: dry the artemisia argyi leaves to constant weight, pulverize, pass through a 60-mesh sieve, use g:mL as 1:6 according to the ratio of material to liquid, reflux extraction with 60% ethanol solution for 1 hour, and keep stirring. Filter after the first extraction, extract the re...
Embodiment 2
[0051] This example provides a traditional Chinese medicine extract with multi-target anti-acne effect and its preparation method:
[0052] (1) The Sophora flavescens extract, its preparation method: dry Sophora flavescens to constant weight, pulverize, pass through a 60-mesh sieve, use g:mL as 1:8 according to the material-liquid ratio, and reflux with 80% ethanol solution Extract for 1 hour, keep stirring, filter after the first extraction, extract the residue once more with 80% ethanol, filter, combine the two filtrates, carry out rotary evaporation to concentrate the filtrate into an extract, and freeze-dry to obtain the Sophora flavescens Extract;
[0053] The preparation method of the Artemisia argyi leaf extract is as follows: dry the leaves of Artemisia argyi to constant weight, crush them, pass through a 60-mesh sieve, and use a 60% ethanol solution to reflux and extract for 1 hour without stopping Stir, filter after the first extraction, extract the residue once mor...
Embodiment 3
[0066] This example provides a traditional Chinese medicine extract with multi-target anti-acne effect and its preparation method:
[0067] (1) Sophora flavescens extract, its preparation method: dry Sophora flavescens to constant weight, pulverize, pass through a 60-mesh sieve, and use 80% ethanol solution to reflux extract for 1 hour according to the ratio of solid to liquid (g:mL) , stirring continuously, filtering after the first extraction, and extracting the residue once with 80% ethanol, filtering, merging the filtrate twice, rotating the filtrate to concentrate into an extract, and freeze-drying to obtain the Sophora flavescens extract ;
[0068] Artemisia argyi extract, its preparation method: dry the artemisia argyi leaves to constant weight, pulverize, pass through a 60-mesh sieve, use g:mL as 1:6 according to the ratio of material to liquid, reflux extraction with 60% ethanol solution for 1 hour, and keep stirring. Filter after the first extraction, extract the re...
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