Medicine for preventing/treating type 2 diabetes and application thereof

A type 2 diabetes and drug technology, applied in the field of medicine, can solve the problems of low survival rate of islets, large blood sugar fluctuations, and difficulty in the source of islets, and achieve the effect of increasing the expression and production of insulin and reducing blood sugar levels

Inactive Publication Date: 2020-07-28
SHENZHEN INST OF ADVANCED TECH
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Problems solved by technology

Among them, hypoglycemic drugs include: sulfonylureas, glinides, GLP-1 receptor agonists, DPP-4 inhibitors, biguanides, thiazolidinediones, direct injection of insulin, etc. It is to control the blood sugar level of the patient, and it needs to be used continuously for a long time, which will affect the quality of life of the patient
And the method of controlling blood sugar may cause the release of insulin not controlled by blood sugar, or the release of blood sugar does not conform to the circadian rhythm, etc. The blood sugar of patients often fluctuates greatly, and it is easy to cause...

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  • Medicine for preventing/treating type 2 diabetes and application thereof
  • Medicine for preventing/treating type 2 diabetes and application thereof
  • Medicine for preventing/treating type 2 diabetes and application thereof

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Embodiment Construction

[0050] The following will clearly and completely describe the technical solutions in the embodiments of the present application with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only some of the embodiments of the present application, not all of them. Based on the embodiments in this application, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the scope of protection of this application.

[0051] Type 2 diabetes T2DM, also known as non-insulin-dependent diabetes mellitus, is a type of disease caused by insulin resistance and relative insufficiency of insulin secretion. The importance of these two factors varies in different patients at different stages of the disease, ranging from predominantly insulin resistance with relative insulin deficiency to predominantly insulin deficiency with insulin resistance. Insulin resistance initiates the pathoge...

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Abstract

The invention provides a medicine for preventing/treating type 2 diabetes and an application thereof, and active ingredients in the medicine take miR-21 as a target spot and promote miR-21 in a targeted manner. In this way, the pancreas islet function can be promoted, and the purpose of reducing blood sugar is achieved.

Description

technical field [0001] The application relates to the technical field of medicines, in particular to a medicine for preventing / treating type 2 diabetes and its use. Background technique [0002] Diabetes is the third largest non-communicable disease after cardiovascular diseases and tumors. It affects more than 300 million people worldwide. The prevention, diagnosis and treatment of diabetes and its complications are key research and development problems in the field of medicine in various countries around the world. major direction. Currently, about 90% of diabetic patients belong to type 2 diabetes mellitus (T2DM). The abnormality of pancreatic β-cell function is the key factor leading to abnormal glucose tolerance in people with normal glucose metabolism and the development of T2DM in people with abnormal glucose tolerance, and it is also a key factor in the gradual progression and deterioration of T2DM patients. [0003] The current treatment methods for T2DM include: ...

Claims

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Application Information

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IPC IPC(8): A61K45/00A61K31/713A61P3/10
CPCA61K45/00A61K31/713A61P3/10
Inventor 阮庆国刘芮伶贺晓珍刘翠莲杨浩然
Owner SHENZHEN INST OF ADVANCED TECH
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