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External pharmaceutical composition as well as preparation method and application thereof

A technology of external drug and composition, applied in the field of external drug composition and its preparation and application, which can solve problems such as anemia and inconvenient movement, and achieve the effect of good curative effect and excellent clinical application prospect

Active Publication Date: 2020-08-04
四川省中医药科学院中医研究所 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Hemorrhoid is a kind of very common clinical common anorectal disease, though not fatal, can show effect at any time, affects people's life and health " its sickness rate is very high, and about 90% are internal hemorrhoids, and internal hemorrhoids take bleeding and prolapse as the main Mainly, long-term repeated bleeding can easily cause anemia, and repeated prolapse can cause mobility inconvenience

Method used

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  • External pharmaceutical composition as well as preparation method and application thereof
  • External pharmaceutical composition as well as preparation method and application thereof
  • External pharmaceutical composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
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Embodiment 1

[0024] Embodiment 1 Preparation of hemorrhoid ointment of the present invention

[0025] Raw material composition:

[0026] Medicinal rhubarb 50g, Coptidis 10g, Burnet 50g, Comfrey 50g, Sophora flavescens 50g, Phellodendron 30g, Dried blood 11.34g, Licorice 22.9g, Bletilla striata 45.73g, Chizhi 1g, Xuanming powder 11.34g, Borneol 3.3g, Borax 6.6 g, myrrh resin 0.5g, frankincense 0.5g, calamine 45.7g;

[0027] Production Process:

[0028] (1) Rhubarb, Coptis chinensis, Burnet, Comfrey, Sophora flavescens, Phellodendron phellodendri, and 500g of palm oil, deep-fried in the same pot until the old yellow color, remove residue, filter, add palm oil to the filtrate to 500ml;

[0029] (2) Dried blood, licorice, bletilla striata, red sesame, xuanming powder, borneol, borax, myrrh, frankincense, calamine: crushed and passed through a 100-mesh sieve;

[0030] (3) Take the above-mentioned medicated oil, heat it to 60°C, add 340g of yellow vaseline, 10g of white wax, stir to dissolve,...

experiment example 1

[0036] Experimental example 1 the clinical curative effect statistics of drug treatment hemorrhoid of the present invention

[0037] (1) Source of patients

[0038] All were recruited from the Outpatient Department of the Second Hospital of Traditional Chinese Medicine of Sichuan Province and the society. A total of 128 patients were recruited, including 61 males and 67 females, aged 18 to 65 years.

[0039] (2) Diagnostic criteria

[0040] Western medicine diagnostic criteria:

[0041] Refer to the diagnostic classification criteria formulated by the first national anorectal academic conference in 1975.

[0042] ①Symptoms:

[0043] Bleeding, dripping, or ejaculation from the anus when defecating.

[0044] Hemorrhoids protrude outside the anus during defecation or after exertion, and can be reset by themselves or by hand.

[0045] Discomfort in the anus when defecating, accompanied by dull pain.

[0046] ② inspection

[0047] The anal margin is red and swollen, and the ...

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Abstract

The invention discloses an external medicine composition which is used for treating haemorrhoids or scalds and is prepared from the following active pharmaceutical ingredients, by weight, 30-80 partsof Chinese rhubarb, 5-30 parts of coptis chinensis, 20-70 parts of sanguisorba officinalis, 30-90 parts of lithospermum erythrorhizon, 20-70 parts of radix sophorae flavescentis, 10-50 parts of cortexphellodendri, 5-30 parts of dragon's blood, 10-40 parts of licorice root, 20-70 parts of bletilla striata, 0.5-5 parts of ganoderma lucidum, 5-30 parts of compound of mirabilitum dehydratum, 1-10 parts of borneol, 3-10 parts of borax, 0.1-10 parts of myrrh, 0.1-3 parts of frankincense and 20-60 parts of calamine. The medicine composition can be used for effectively treating haemorrhoids and has an excellent application prospect.

Description

technical field [0001] The invention relates to a pharmaceutical composition for external use, a preparation method and application thereof. Background technique [0002] Hemorrhoid is a kind of very common clinical common anorectal disease, though not fatal, can show effect at any time, affects people's life and health " its sickness rate is very high, and about 90% are internal hemorrhoids, and internal hemorrhoids take bleeding and prolapse as the main Mainly, long-term repeated bleeding can easily cause anemia, and repeated prolapse can cause inconvenience. With the progress of research on the etiology, pathology and mechanism of hemorrhoids, people have gradually realized that non-surgical treatment should be the first choice for the treatment of hemorrhoids. Except for severe internal hemorrhoids and mixed hemorrhoids In addition to surgical treatment as the first choice for hemorrhoid patients, drug treatment is generally the first choice for other mild to moderate pa...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P9/14A61P17/02A61K31/045A61K33/04A61K33/22A61K33/30
CPCA61K36/708A61K36/718A61K36/739A61K36/30A61K36/489A61K36/756A61K36/889A61K36/896A61K36/484A61K36/898A61K36/074A61K33/04A61K31/045A61K33/22A61K36/328A61K36/324A61K33/30A61K9/0014A61K47/44A61P17/02A61P9/14A61K2300/00
Inventor 毛红罗霞赵希忠许晓燕赵强江南杨军义康进唐平
Owner 四川省中医药科学院中医研究所