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Degradable spring coil system for treating intracranial aneurysm

A technology of intracranial aneurysms and coils, which is applied in the field of medical devices, can solve the problems of rapid thrombosis due to the mass effect of coils, expensive metal materials of coils, etc., so as to avoid acute bleeding, solve material cost problems, and avoid occupying space effect of effect

Pending Publication Date: 2020-10-16
SHANDONG BRANDEN MEDICAL DEVICE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Aiming at the deficiencies in the prior art, the present invention provides a degradable coil system for the treatment of intracranial aneurysms, which mainly solves the problems of expensive coil metal materials, space occupation effect of coils and rapid thrombosis

Method used

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  • Degradable spring coil system for treating intracranial aneurysm
  • Degradable spring coil system for treating intracranial aneurysm

Examples

Experimental program
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Effect test

Embodiment 1

[0032] In this embodiment, a degradable coil system for treating aneurysms includes: 1 microcatheter, 2 stainless steel guide wire, 3 metal coil body and 31 drug coating coated on the surface of the metal coil. 33 The body of the metal spring coil is made of zinc-iron-copper material, and the mass percentage is 95% zinc, 4% iron, and 1% copper. The diameter of the metal spring ring body is 0.30-0.40mm. According to different requirements of spring softness, the optimum range of spring wire diameter is 0.03-0.05mm.

[0033] The surface of the wire is porous-treated to form 32 porous surfaces. figure 2 It is an enlarged schematic diagram of the partially degradable medical coil filling the aneurysm or arteriovenous malformation in the released state after being released through the catheter delivery system. Thrombosis-promoting drugs (such as snake venom hemocoagulase, vitamin K) are coated on the surface of the degradable coil by ultrasonic spraying, and the drug loading is ...

Embodiment 2

[0038] The degradable medical coil of this embodiment is substantially the same as that of the first embodiment, except that the body of the bare metal coil is made of a zinc-iron-copper alloy material.

[0039] In the zinc-iron-copper alloy material, the mass percentages of various components are as follows: zinc is 90%; iron is 8%; copper is 2%.

[0040] Experiments have proved that the degradable medical coil meets the application requirements.

Embodiment 3

[0042] The degradable medical coil of this embodiment is substantially the same as that of the first embodiment, except that the body of the bare metal coil is made of a zinc-iron-copper alloy material.

[0043] In the zinc-iron-copper alloy material, the mass percentages of various components are as follows: zinc is 93%; iron is 6%; copper is 1%.

[0044] Experiments have proved that the degradable medical coil meets the application requirements.

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Abstract

The invention belongs to a nervous intervention technique in the field of medical equipment and particularly relates to a degradable spring coil system for treating intracranial aneurysm. The degradable spring coil system comprises a porous bare metal spring coil body prepared from a degradable zinc alloy wire, a drug coating coating the surface of a spring coil, a guide wire and a microcatheter.According to the degradable spring coil system, a degradable metal material zinc is applied to preparation of the spring coil; through adjusting the ratio of various metal materials in an alloy, the degradation rate of the spring coil in arterial aneurysm is controlled and the biocompatibility of the spring coil after being implanted is improved. Through a porous structure of the degradable springcoil system, procoagulant drugs are easily adhered, and the procoagulant drugs are released into surrounding blood and tissue under current and ultrasonic stimulation or in a natural degradation process, so that healing of hemangioma is further promoted. The degradable spring coil disclosed by the invention are rich and easily available in material, good in safety and low in cost, is suitable formass production and has relatively high application value.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a degradable coil system for treating aneurysms. Background technique [0002] Intracranial aneurysms are formed by localized bulging of the arterial wall of a blood vessel. As the aneurysm grows, the vessel wall becomes less compliant and more tense, and the aneurysm can rupture. Ruptured aneurysms can cause cerebral vasospasm, disturbance of consciousness, neurological dysfunction, and even death. At present, the surgical methods for intracranial aneurysms mainly include microsurgical clipping, endovascular intervention, and extracranial artery bypass grafting. In recent years, due to the advantages of less trauma and faster recovery, vascular intervention has become a treatment method with broad prospects. In addition, in the treatment of some aneurysms with deep location, high risk of craniotomy, difficult surgical clipping or difficult separation from surrounding ...

Claims

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Application Information

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IPC IPC(8): A61B17/12
CPCA61B17/12113A61B17/1204A61B17/1215A61B2017/1205A61B2017/12059A61B2017/1209A61B2017/00893A61B2017/00004
Inventor 张海军刘爱华田振凡曹明昆侯文博尹玉霞鲁手涛袁坤山段翠海
Owner SHANDONG BRANDEN MEDICAL DEVICE