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A prebiotic combination that effectively reduces blood sugar, blood lipids and body weight in patients with type 2 diabetes

A technology of type 2 diabetes and prebiotics, applied in the direction of drug combinations, medical preparations containing active ingredients, microorganisms, etc., can solve problems such as abdominal discomfort, vomiting and diarrhea, and affect the physiological functions of patients, so as to improve blood sugar and eliminate toxins. Side effects, effect of lowering serum cholesterol level

Active Publication Date: 2022-04-22
WUHAN UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, practice has shown that this type of dietary fiber is difficult to digest and absorb, and a slight dose of carelessness can lead to adverse reactions such as abdominal discomfort, flatulence, anorexia, nausea, vomiting and diarrhea, and even affect the normal physiological functions of patients in severe cases.

Method used

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  • A prebiotic combination that effectively reduces blood sugar, blood lipids and body weight in patients with type 2 diabetes
  • A prebiotic combination that effectively reduces blood sugar, blood lipids and body weight in patients with type 2 diabetes
  • A prebiotic combination that effectively reduces blood sugar, blood lipids and body weight in patients with type 2 diabetes

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A prebiotic combination for efficiently reducing blood sugar, blood fat and body weight in patients with type 2 diabetes. The prebiotic combination is composed of 30% lactulose, 30% arabinose and 40% plantarum CGMCC 8198 in terms of weight percentage.

Embodiment 2

[0027] A prebiotic combination for efficiently reducing blood sugar, blood fat and body weight in patients with type 2 diabetes. The prebiotic combination is composed of 20% lactulose, 40% arabinose and 40% plantarum CGMCC 8198 by weight percentage.

Embodiment 3

[0029] A prebiotic combination for efficiently reducing blood sugar, blood fat and body weight in patients with type 2 diabetes. The prebiotic combination is composed of 40% lactulose, 20% arabinose and 40% plantarum CGMCC 8198 by weight percentage.

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Abstract

The invention relates to the technical field of functional food, in particular to a combination of prebiotics that can efficiently reduce blood sugar, blood fat and body weight of patients with type 2 diabetes. The prebiotic combination consisting of lactulose, arabinose and Lactobacillus plantarum can effectively improve blood sugar, blood lipid and body weight levels in patients with type 2 diabetes. The present invention not only provides an important theoretical basis for elucidating the mechanism of intestinal microecological regulation affecting the therapeutic effect of diabetes, but also introduces the combination of prebiotics into the dietary treatment plan for type 2 diabetes, providing a new method for clinically improving the curative effect of type 2 diabetes. way.

Description

technical field [0001] The invention relates to the technical field of functional food, in particular to a combination of prebiotics that can efficiently reduce blood sugar, blood fat and body weight of patients with type 2 diabetes. Background technique [0002] Studies have shown that the increase in the incidence of diabetes is not only due to genetics, improper diet or reduced physical activity, gut microbiota may play a more important role in it. The intestinal microflora is symbiotic with humans, but it has 150 times the human genes, and the massive genetic information it contains may become a new target for diabetes prevention and treatment. The literature has reported a close relationship between gut flora and type 2 diabetes mellitus (T2DM): the ratio of Bacteroidetes to Firmicutes and the ratio of Bacteroides prausnitzii to Enterococci in the intestines of T2DM patients were positively correlated with blood glucose levels, It has nothing to do with body mass index...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/20A61K35/747A61K31/7016A61K31/7004A61P3/10A61P3/06A61P3/04A23L33/125A23L33/135C12R1/25
CPCA61K31/7016A61K31/7004A61K35/747A61P3/10A61P3/06A61P3/04A23L33/125A23L33/135A23V2002/00A61K2300/00A23V2200/3262A23V2200/328A23V2200/332
Inventor 张同存周翔王琼杨杨
Owner WUHAN UNIV OF SCI & TECH