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Application of bougainvillea glabra

A technology of the effect of Bougainvillea glabra, applied in the field of medical and health products, can solve problems such as unfavorable product quality and stability of curative effect, incomplete application and development of Bougainvillea glabra, and no scientific interpretation of medicinal effects, etc., achieving good development and application prospects, Anti-alcoholic, liver-protecting, hypoglycemic and lipid-lowering effects, and the effect of avoiding acetaldehyde poisoning and allergic symptoms

Inactive Publication Date: 2020-10-27
ANHUI DEXIN HUAHAI BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] The purpose of the present invention is to provide the application of Bougainvillea glabra, to solve the incomplete application and development of the existing Bougainvillea glabra, the existing preparation procedures are lengthy, which is not conducive to the stability of product quality and curative effect, and there is no in-depth scientific research on the efficacy of the drug. problem of interpretation

Method used

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  • Application of bougainvillea glabra
  • Application of bougainvillea glabra
  • Application of bougainvillea glabra

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] The preparation method of light bougainvillea of ​​the present invention

[0054] 1. The application of the branches and leaves of the light bougainvillea

[0055] 1. Preparation of boiling liquid:

[0056] Picking and selection of original leaves: select leaf buds or young leaves with light green color, no disease spots, and no pests, wash them, remove dust and microorganisms on the leaf surface, drain the water, and spread them evenly in a ventilated and dry place;

[0057] Withering: naturally wither for 3 hours, and turn it up and down once in the middle, until the leaves are soft and the water loss rate is about 8%.

[0058] Boiling: Boil the withered glabra leaves and pure water for 2 hours according to the material ratio of 1:20, collect the extract, and boil again for 2 hours at the material ratio of 1:15, and collect the extract; Filtration: use the collected extract with 12 layers Filter through sterile gauze, collect the filtrate to obtain the boiling liqui...

Embodiment 2

[0087] Research on anti-alcoholic and liver-protecting effect of the present invention

[0088] 1. Materials

[0089] 1. Experimental animals

[0090] SPF male Kunming mice, weighing 18-20 g, were provided by the Comparative Medicine Center of Yangzhou University, certificate number: SCXK (Su) 2017-0007.

[0091] 2. Drugs and reagents

[0092] Boiled liquid of leaves and leaves of leaves: (see Example 1 for detailed preparation). During the experiment, a solution of corresponding concentration was prepared with sterile water for intragastric administration of mice. The dosage for mice is 750 mg crude drug amount / kg, which is equivalent to 5.71 g crude drug amount / day for a 70 kg adult in terms of body surface area.

[0093] Hot water soaking solution of leaves and leaves of leaves: (see Example 1 for detailed preparation). During the experiment, a solution of corresponding concentration was prepared with sterile water for intragastric administration of mice. The dosage f...

Embodiment 3

[0136] Research on hypoglycemic and lipid-lowering activity of the present invention

[0137] 1. Test method:

[0138] animal husbandry

[0139] Take 8 male C57BL / 6 mice as the normal control group, take a number of dbdb male mice aged 7-8 weeks and feed them adaptively for one week, fast for 12 hours, cut off the tail to take blood, measure fasting blood sugar with a blood glucose meter, and select fasting blood sugar ≥ 11.1 The dbdb mice of mmol / L are type II diabetic mice.

[0140] 2. Administration of animals in groups

[0141] Modeled dbdb mice are divided into 15 groups: model control group, positive control group (pioglitazone hydrochloride sheet, Jiangsu Deyuan Pharmaceutical Co., Ltd.), the boiling liquid of glabra leaves of the present invention (750mg crude drug amount / kg), this Invented hot water soaking solution (750mg crude drug amount / kg) of the light leaf flower branches and leaves of the present invention, normal temperature soaking solution (750mg crude dr...

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Abstract

The invention discloses application of bougainvillea glabra and belongs to the technical field of medicines. The application is mainly used for developing fresh branches and leaves of the bougainvillea glabra, is low in cost, has remarkable social and market values and has a good development application prospect. Flowers and / or bracts and / or branches and / or leaves of the bougainvillea glabra can improve activity of acetaldehyde dehydrogenase and inhibit spirit-induced abnormal increase of glutamate-pyruvate transaminase and glutamic-oxalacetic transaminase and has the effects of dispelling effect of alcohol and protecting livers; and meanwhile, the bougainvillea glabra can be used for reducing blood sugar of mice suffering from type II diabetes, reducing blood fat, improving oral-administration sugar tolerance, obviously lowering insulin resistance, and the like, can be used for preparing health-care foods of a blood sugar reducing type, blood fat reducing type and insulin resistance relieving type and has health-care actions of reducing blood sugar and blood fat on people such as sufferers suffering from hyperglycemia, hyperlipemia and insulin resistance of the type II diabetes. The health-care foods are low in toxic or side effects and stable in quality.

Description

technical field [0001] The invention belongs to the field of medicine and health care products, and specifically relates to a product that can increase the activity of acetaldehyde dehydrogenase, inhibit the abnormal increase of alanine aminotransferase and aspartate aminotransferase caused by alcohol, and has the functions of lowering blood sugar, blood fat, improving glucose tolerance, and reducing insulin resistance. It can be used to prepare anti-alcoholic, liver-protecting, blood-sugar-lowering, blood-fat-lowering, and insulin-resistance-reducing health foods. Background technique [0002] China is a big country in the production and consumption of alcoholic beverages. The annual consumption of alcoholic beverages has reached more than 10,000 tons. There are about 100 million people who are addicted to alcohol or alcohol dependent, and the rate of acute and chronic alcoholism is increasing day by day. [0003] Alcoholism is mainly caused by ethanol, the main component i...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P1/16A61P3/10A61P3/06A23L33/105A61K133/00A61K127/00A61K135/00
CPCA23V2002/00A61K36/185A23L33/105A61P1/16A61P3/06A61P3/10A23V2200/32A23V2200/328A23V2200/3262
Inventor 康梦实戚微岩于瑞河
Owner ANHUI DEXIN HUAHAI BIOLOGICAL TECH CO LTD
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