The invention provides an oral medicine for treating the fatty liver. The oral medicine is prepared through using radix bupleuri, Artemisia capillaries, white peony root, Fructus Amomi, Rhizoma Sparganii, Polygonum multiflorum, haw, alga, Rhizoma Curcumae, safflower, Fructus Aurantii, Radish Seed, Fructus Toosendan, Immature Bitter Orange, Radix Codonopsis, Flos Citri Sarcodactylis, Rhizoma Polygoni Cuspidati, Ligusticum wallichii, Rhizoma Cyperi, Semen Cassiae, Abrus cantoniensis, Longstamen Onion Bulb, Rheum officinale, Herba Taraxaci, Rhizoma Alismatis, Caulis Perillae, Poria cocos, Pinellia Tuber, Pericarpium Arecae, Ligustri Lucidi Fructus, Rhizoma Coptidis, Polyporus Umbellatus, Bletilla striata, Rhizoma curcumae longae, Polygonatum sibiricum, Gentiana scabra Bunge, lotus leaf, coix seed, Luffa Vegetable Sponge and Fortune Eupatorium Herb. The oral medicine treats blood quickening, stasis dispelling, spleen invigorating, liver nourishing, dampness dispelling, yin nourishing and body fluid generating as a treatment principle, can simultaneously treat principal and subordinate symptoms, can realize the unblocked blood vessel operation, sufficient body fluid, healthy spleen and liver operation, and sufficient cerebral blood circulation, treats a series of clinic symptoms caused by the fatty liver, delays the generation of fatty liver pathologies, and improves the working and living qualities of persons.