Rabbit coccidiosis attenuated live vaccine suspending aid for drinking water immunization and preparation method of rabbit coccidiosis attenuated live vaccine suspending aid

A live attenuated vaccine, rabbit coccidiosis technology, applied in the field of immunobiology, can solve the problem of suspension stability, difficult rabbit coccidiosis live attenuated vaccine and other problems

Active Publication Date: 2020-10-27
INNER MONGOLIA AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, when the coccidiosis vaccine suspending agent applied to chickens in the prior art is applied to the live attenuated vaccine of rabbit coccidiosis, there will be problems in the suspension stability
In addition, it is also necessary to consider the possible adverse effects of the suspending agent on the vaccine and the animal body, and it is more difficult to directly apply the coccidiosis vaccine suspending agent used in chickens to the live attenuated coccidiosis vaccine in rabbits

Method used

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  • Rabbit coccidiosis attenuated live vaccine suspending aid for drinking water immunization and preparation method of rabbit coccidiosis attenuated live vaccine suspending aid
  • Rabbit coccidiosis attenuated live vaccine suspending aid for drinking water immunization and preparation method of rabbit coccidiosis attenuated live vaccine suspending aid
  • Rabbit coccidiosis attenuated live vaccine suspending aid for drinking water immunization and preparation method of rabbit coccidiosis attenuated live vaccine suspending aid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] This example provides a suspension of live attenuated coccidiosis vaccine for drinking water, containing 0.3‰ of carrageenan and 0.3‰ of KCl in mass percentage.

[0029] This embodiment further provides a method for preparing the suspension of the rabbit coccidiosis live attenuated vaccine suspension for drinking water immunization. Carrageenan and KCl are mixed to form an aqueous solution at a temperature above 60°C.

Embodiment 2

[0031] This example provides a suspension of live attenuated coccidiosis vaccine for drinking water immunization, which contains 0.6‰ of carrageenan and 0.6‰ of KCl in mass percentage.

[0032] The preparation method is the same as in Example 1.

Embodiment 3

[0034] This example provides a suspension of live attenuated coccidiosis vaccine for drinking water immunization, which contains 0.3‰ of carrageenan and 0.5‰ of KCl in mass percentage.

[0035] The preparation method is the same as in Example 1.

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Abstract

The invention relates to the field of immunobiology, in particular to a rabbit coccidiosis attenuated live vaccine suspending aid for drinking water immunization and a preparation method of the rabbitcoccidiosis attenuated live vaccine suspending aid. The rabbit coccidiosis attenuated live vaccine suspending aid for drinking water immunization comprises 0.03% to 0.06% of carrageenan and 0.03% to0.06% of KCl. According to the suspending aid disclosed by the invention, rabbit coccidiosis oocysts can be uniformly suspended in drinking water and are not settled after 8 hours, so that the uniformity of vaccine oocysts ingested by rabbits is improved, and the immune effect is improved. Moreover, the components of the suspending aid are simplified as much as possible, and meanwhile, the dosageof the components is reduced, so that the influence of the suspending aid on vaccines and rabbits can be avoided to the maximum extent, and the production cost is favorably reduced.

Description

technical field [0001] The invention relates to the field of immunobiology, in particular to a suspension agent of live attenuated coccidiosis vaccine for drinking water and a preparation method thereof. Background technique [0002] Rabbit coccidiosis is one of the most serious infectious diseases that harm the intensive rabbit breeding industry. It has a high infection rate in the domestic rabbit (Oryctolagus cuniculus) population and is highly pathogenic. It is extremely harmful to the rabbit breeding industry and is listed as a national The second type of animal disease is listed as the four major rabbit diseases together with rabbit plague, rabbit pasteurellosis and rabbit mange. The pathogen of this disease is rabbit Eimeria spp. (rabbitEimeria spp.), and it belongs to apicomplexa (Apicomplexa), sporozoa (Sporozoa), coccidia (Coccidia), coccidia (Coccidiida), Eimeiria. There are many kinds of coccidia in the genus Eimeria rabbits, and 25 species of coccidia have been...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/36A61K47/02A61K39/012A61P33/02
CPCA61K47/36A61K47/02A61K39/012A61P33/02A61K2039/522A61K2039/542A61K2039/552
Inventor 闫鑫磊郭军王鹤静韩汶荧杜权马宇轩
Owner INNER MONGOLIA AGRICULTURAL UNIVERSITY
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