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Preparation method of Chinese herbal medicine wall-broken decoction pieces

A technology of broken-walled decoction pieces and Chinese herbal medicines, which can be applied to medical formulas, medical preparations containing active ingredients, etc. The surface permeability is enhanced, the modification effect is improved, and the effect of intermixing effect is enhanced

Inactive Publication Date: 2020-10-30
广东汇群中药饮片股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the broken-wall decoction piece technology is not widely used in domestic decoction piece production enterprises, and no real industry norms have been formed.
[0003] The following problems occur in Chinese herbal medicine using the existing wall-breaking technology: 1. Using ultra-micro technology, the dissolution rate of active substances in Chinese herbal medicine is low; 2. The particle size of Chinese herbal medicine obtained by using ultra-micro technology is reduced, the specific surface area is increased, and the interaction between drugs Force enhancement, easy to reunite, difficult to disperse, affect the preparation of medicines, in view of this, the invention provides a kind of preparation method of Chinese herbal medicine broken wall decoction pieces

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A kind of preparation method of Chinese herbal medicine broken wall decoction piece of the present embodiment, comprises the following steps:

[0025] Step 1, pretreatment of Chinese herbal medicines: (1) surface modification: place Chinese herbal medicines in a plasma box for 1 min, with a working current of 0.2A and an air pressure of 1Mpa, and then proton irradiation treatment for 2 min;

[0026] (2) Solution modification: Put (1) modified Chinese herbal medicine into the treatment solution and stir for 15 minutes at a speed of 100r / min. After the stirring is completed, then homogeneously treat, finally centrifuge, wash with water, and dry. ;

[0027] Step 2, coarse powder of Chinese herbal medicines: pulverize the Chinese herbal medicines processed in step 1 to 200 meshes with a pulverizer, and then continue to grind them to 100 meshes with a 1000r / min grinder;

[0028] Step 3, Chinese herbal medicine micropowder: send the coarsely powdered Chinese herbal medicine ...

Embodiment 2

[0037] A kind of preparation method of Chinese herbal medicine broken wall decoction piece of the present embodiment, comprises the following steps:

[0038] Step 1, pretreatment of Chinese herbal medicines: (1) Surface modification: place Chinese herbal medicines in a plasma box for 3 minutes, with a working current of 1A and an air pressure of 2Mpa, and then use proton irradiation for 4 minutes;

[0039] (2) Solution modification: send the modified Chinese medicinal material into the treatment solution and stir at a speed of 200r / min for 15-25min, after the stirring is completed, then homogenize, finally centrifuge, wash with water, and dry. can;

[0040] Step 2, coarse powder of Chinese medicinal materials: the Chinese medicinal materials processed in step 1 are pulverized to 400 mesh with a pulverizer, and then continue to be ground to 200 mesh with a grinder at 1500 r / min;

[0041] Step 3, micropowder of Chinese herbal medicines: send the coarsely powdered Chinese herbal...

Embodiment 3

[0050] A preparation method of Chinese herbal medicine broken wall decoction pieces, comprising the following steps:

[0051] Step 1, pretreatment of Chinese herbal medicines: (1) surface modification: place Chinese herbal medicines in a plasma box for 2 minutes, with a working current of 0.6A and an air pressure of 1.5Mpa, and then use proton irradiation for 3 minutes;

[0052] (2) Solution modification: put the modified Chinese herbal medicine into the treatment solution and stir at a speed of 150r / min for 20 minutes, after the stirring is completed, then homogeneously treat, finally centrifuge, wash with water, and dry. ;

[0053] Step 2, coarse powder of Chinese herbal medicines: pulverize the Chinese herbal medicines processed in step 1 to 300 meshes with a pulverizer, and then continue to grind them to 150 meshes with a grinder at 1000-1500 r / min;

[0054] Step 3, micropowder of Chinese herbal medicines: the coarsely powdered Chinese herbal medicines were frozen at -5°C...

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Abstract

The invention provides a preparation method of Chinese herbal medicine wall-broken decoction pieces, which comprises the following steps: step 1, pretreatment of traditional Chinese medicinal materials: (1) surface modification: treating the traditional Chinese medicinal materials in a plasma box for 1-3 minutes under the conditions that the working current is 0.2-1A and the air pressure is 1-2 Mpa, and then performing proton irradiation treatment for 2-4 minutes. According to the method, the traditional Chinese medicinal materials are modified in a surface physics and solution chemistry combined mode, plasma and proton irradiation treatment is adopted for surface modification, the surface microstructure of the traditional Chinese medicinal materials can be damaged, and a basis is providedfor subsequent chemical solution modification.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a preparation method of broken-wall decoction pieces of Chinese herbal medicines. Background technique [0002] Broken-wall decoction pieces of traditional Chinese medicine is a traditional Chinese medicine decoction piece processed in powder form by using modern ultrafine pulverization technology. Broken wall decoction pieces of traditional Chinese medicine are all ingredients used as medicine, and the medicinal material basis remains unchanged, which is in line with the connotation of Chinese medicine decoction pieces. It can be directly brewed and taken together with the dregs of the medicine. However, the broken-wall decoction pieces technology is not widely used in domestic decoction pieces production enterprises, and no real industry norms have been formed. [0003] The following problems occur in Chinese herbal medicine using the existing wall-break...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/00A61K47/36A61K47/02
CPCA61K36/00A61K47/02A61K47/36A61K2236/15
Inventor 李春泉黄聪林泳冰陈德宾
Owner 广东汇群中药饮片股份有限公司
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