Preparation method of lignan compound and application thereof

A technology of lignans and compounds, which is applied in the field of medicine, can solve the problems of unclear active ingredients, unclear substances that act on liver diseases, etc., and achieve the effect of reducing the content
CN111925404AActive Publication Date: 2020-11-13JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE +1
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
Publication Date
2020-11-13

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Abstract

The invention relates to the technical field of medicines, in particular to a preparation method of a lignan compound in sabia parviflora and an application thereof, and further provides an application of the lignan compound in preparation of medicines or health care products for preventing and treating fatty liver injury. The pharmacological studies show that the compound provided by the invention can significantly reduce a large amount of cell apoptosis caused by FFA treatment of LO2 cells, can reduce the cell apoptosis rate caused by FFA when the concentration of the compound is greater than 2.5 [mu]g / ml, and has concentration dependence; meanwhile, when the concentration of the compound is greater than 2.5 [mu]g / ml, the content of Albumin can be up-regulated; the activity of AST and ALT is weakened, and the content of TG is reduced, so that the compound has a protective effect on FFA-induced liver normal cell damage, and is expected to be developed into a new medicine or health care product for preventing and treating fatty liver injury diseases.
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Description

technical field

[0001] The invention relates to the technical field of medicines, in particular to a preparation method and application of a lignan compound in Teng hua qingfeng. Background technique

[0002] Xiaohua Qingfengteng is a liana of Qingfeng rattan family Qingfeng rattan, Xiaohua Qingfengteng Sabia parviflora Dried stems and leaves of Wall. exRoxb. The small flower Qingfengteng produced in Guizhou is a folk medicine of the Buyi and Miao nationalities. It is mainly distributed in Xingyi City, Anlong County, Ceheng County, Wangmo County and other places in Guizhou. Its rhizomes and leaves can be used as medicine. Anti-inflammatory and analgesic effects, the treatment of viral hepatitis A and B has remarkable curative effect, and the side effects are small. Its related varieties are mostly used clinically for diseases related to the liver. However, the main active ingredients in Qingfengteng are unknown at present, and the active substances of its liver diseases ar...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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