Processing method of polymer pipe for intravascular stent

A technology for polymer tubes and vascular stents, applied in the field of medical devices, can solve the problems of low fracture strength, small radial support force, and poor mechanical properties of stents, so as to improve the fracture strength and increase the radial support force. , the effect of excellent mechanical properties

Pending Publication Date: 2020-12-11
乐普(深圳)国际发展中心有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The advantages of degradable stents are many, but the mechanical properties of polymer stents are poor. Most polymer stents have small radial support force and low breaking strength, which limits the application of degradable stents.

Method used

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  • Processing method of polymer pipe for intravascular stent
  • Processing method of polymer pipe for intravascular stent

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] (a) Heat the extruded polylactic acid polymer pipe 3 to 55°C, the polymer pipe 3 softens, and keep it warm at the 55°C for 20min, the wall thickness of the polymer pipe 3 is 500um;

[0024] (b) Put the heated polymer pipe 3 into the cavity of the mold 1 quickly, and feed hot air at 55°C at a constant speed into the polymer pipe 3, and the pipe 3 in the cavity is heated by the hot air. under the action of expansion and deformation in the radial direction, and the outer wall of the expanded pipe 3 is attached to the inner wall of the mold 1;

[0025] (c) Open the circulating cooling water in the mold 1, and pass cold air at 20°C into the pipe 3. The cold air inside the mold 1 and the pipe 3 with a lower temperature acts on the pipe 3 at the same time, and the pipe 3 is quickly cooled. The heat is taken away, so that the pipe material 3 is rapidly cooled to room temperature, and the mold is opened to obtain a deformed pipe material 3 with a wall thickness of 100um.

[002...

Embodiment 2

[0029] (a) Heat the extruded polylactic acid polymer pipe 3 to 60°C, the polymer pipe 3 softens, and keep it warm at the temperature of 60°C for 10 minutes, and the wall thickness of the polymer pipe 3 is 600um;

[0030] (b) Put the heated polymer pipe 3 into the cavity of the mold 1 quickly, and feed hot air at 60°C at a constant speed into the polymer pipe 3, and the pipe 3 in the cavity is heated by the hot air. under the action of expansion and deformation in the radial direction, and the outer wall of the expanded pipe 3 is attached to the inner wall of the mold 1;

[0031] (c) Open the circulating cooling water in the mold 1, and pass cold air at 20°C into the pipe 3. The cold air inside the mold 1 and the pipe 3 with a lower temperature acts on the pipe 3 at the same time, and the pipe 3 is quickly cooled. The heat is taken away, the pipe 3 is quickly cooled to room temperature, and the mold is opened to obtain the deformed pipe 3 with a wall thickness of 200um.

[003...

Embodiment 3

[0035] (a) Heat the extruded polylactic acid polymer pipe 3 to 65°C, the polymer pipe 3 softens, and keep it warm at 65°C for 10 minutes, and the wall thickness of the polymer pipe 3 is 500um;

[0036] (b) Put the heated polymer pipe 3 into the cavity of the mold 1 quickly, and feed hot air at 70°C at a constant speed into the polymer pipe 3, and the pipe 3 in the cavity is heated by the hot air. under the action of expansion and deformation in the radial direction, and the outer wall of the expanded pipe 3 is attached to the inner wall of the mold 1;

[0037] (c) Turn on the circulating cooling water in the mold 1, and pass cold air at 25°C into the pipe 3. The cold air inside the mold 1 and the pipe 3 with a lower temperature acts on the pipe 3 at the same time, and the pipe 3 will be quickly The heat is taken away, so that the pipe material 3 is rapidly cooled to room temperature, and the mold is opened to obtain a deformed pipe material 3 with a wall thickness of 100um.

...

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Abstract

The invention discloses a processing method of a polymer pipe for an intravascular stent. The processing method comprises the following steps that (a) a formed polymer pipe is heated to a first temperature, and the temperature is kept for 10-20 minutes; (b) the heated polymer pipe is rapidly placed into a cavity of a mold, hot air is introduced into the polymer pipe at a constant speed, the pipe expands and deforms in the radial direction under the action of the hot air, and the outer wall of the expanded pipe is attached to the inner wall of the mold; (c) circulating cooling water is turned on, cold air is introduced into the pipe, the pipe is quickly cooled to room temperature, and the mold is opened to obtain a deformed pipe; and the mold is provided with a cooling water tank, and circulating cooling water is introduced into the cooling water tank. The pipe expands in the mold and is quickly cooled under the action of the mold, so that the orientation of polymer is kept, the breaking strength of the polymer is improved, and the supporting performance of the polymer pipe is enhanced.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and in particular relates to a processing method for a polymer pipe used for vascular stents. Background technique [0002] Vascular stents for coronary intervention include permanent bare metal stents, drug-eluting permanent metal stents, and degradable polymer stents. The biodegradable polymer stent is made of biodegradable materials, which can support the blood vessel after being implanted in the lesion, and rebuild the blood supply function of the blood vessel. After the treatment is completed, the degradable stent degrades into a Toxic products are excreted from the body through normal metabolism and disappear. Degradable stents have many advantages, but the mechanical properties of polymer stents are poor. Most polymer stents have small radial support force and low breaking strength, which limit the application of degradable stents. Contents of the invention [0003] The object ...

Claims

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Application Information

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IPC IPC(8): B29C61/04B29L23/00B29L31/00
CPCB29C61/04B29L2023/00B29L2031/753
Inventor 戴燕陈果何成
Owner 乐普(深圳)国际发展中心有限公司
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