Compound brain protein hydrolysate tablet and preparation process thereof

Abstract

The invention discloses a compound brain protein hydrolysate tablet and a preparation process thereof, and relates to the technical field of medicine processing. The compound brain protein hydrolysatetablet is prepared from the following components in parts by mass: 60-75 parts of brain protein hydrolysate, 6-7 parts of glutamic acid, 6-7 parts of sodium chondroitin sulfate, 11-13 parts of microcrystalline fibers, 10-12 parts of vitamin B1, 0.1-0.3 part of vitamin B6, 7-9 parts of dextrin, 8-10 parts of calcium carbonate, 10-12 parts of corn starch, 3-5 parts of magnesium stearate for coating, 100-130 parts of sucrose and 60-70 parts of talcum powder. The preparation process comprises the following steps: sequentially granulating the raw materials, drying, granulating and totally mixing,tabletting, coating, and airing, thereby obtaining the compound brain protein hydrolysate tablet. The coating is performed in three steps, namely an isolation layer, a powder coating layer and a colored sugar coating layer. The coating raw materials are prepared from syrup, so that the disintegration time of the coating is accelerated, the drug effect time is prolonged, and the taste of the compound brain protein hydrolysate is guaranteed.

Description

technical field [0001] The disclosure belongs to the technical field of pharmaceutical processing, and in particular relates to a compound cerebroprotein hydrolyzate tablet and a preparation process thereof. Background technique [0002] Cerebroprotein hydrolyzate is an aqueous solution of a mixture of various amino acids and low-molecular-weight peptides obtained by enzymatic hydrolysis of animal brain tissue proteins. It is a unique peptide energy neurotrophic drug for the brain, which can act on the central nervous system in various ways to regulate And improve the metabolism of neurons, promote the formation of synapses, induce the differentiation of neurons, and further protect nerve cells from various ischemia and neurotoxin damage. It is used to improve symptoms such as insomnia, headache, memory loss, dizziness and irritability, and can promote the rehabilitation of sequelae of brain trauma, sequelae of cerebrovascular diseases, sequelae of encephalitis, acute cerebr...

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Problems solved by technology

[0003] At present, the commonly used dosage forms of cerebroprotein hydrolyzate preparations mainly include injections, oral tablets, etc., among which oral tablets are film-coated tablets. tablet, coating, packaging and other steps, the role of the coating not only facilitates the storage of the tablet, but also its disintegration time directly affects the efficacy of the drug. Aiming at the problem that the existing coating is not easy to disintegrate, we propose a A kind of compound cerebroprotein hydrolyzate sheet and its preparation process

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