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Preparation method of active peptide sterilization antiviral spray

A production method and anti-virus technology, which is applied in the direction of anti-viral agent, anti-inflammatory agent, aerosol delivery, etc., can solve the problems of poor inactivation effect, and achieve the effect of promoting mucosal repair, inhibiting replication, and inhibiting inflammation

Pending Publication Date: 2021-01-05
合肥天泰医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Existing antiviral sprays have poor inactivation effect on COVID-19 (i.e. novel coronavirus), so we propose a method for making active peptide bactericidal antiviral spray to solve the above problems

Method used

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  • Preparation method of active peptide sterilization antiviral spray

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] refer to figure 1 , a preparation method of an active peptide bactericidal antiviral spray, comprising the following components in mass percentage: 20% antiviral active polypeptide, 20% antiviral active agent, 10% auxiliary antibacterial agent, 10% taste masking agent, and 40% solvent , the content of the antiviral active polypeptide and the auxiliary antibacterial agent is 30%;

[0020] The preparation method comprises the following steps:

[0021] 1) Spray mixing: mix the antiviral active polypeptide, antiviral active agent, auxiliary antibacterial agent, taste masking agent and solvent in proportion to obtain a drug mixture, and add the drug mixture to a mixing container and mix at high speed;

[0022] 2) Atomization of the spray: add the drug mixture into the atomization device, which is preferably an air compression atomizer, a heating atomizer, a vibrating mesh microporous atomizer or an ultrasonic atomizer.

[0023] The antiviral active polypeptide is a viral p...

Embodiment 2

[0025] refer to figure 1 , a method for making an active peptide bactericidal antiviral spray, comprising the following components in mass percentage: 20% antiviral active polypeptide, 25% antiviral active agent, 10% auxiliary antibacterial agent, 10% taste masking agent, and 35% solvent , the content of the antiviral active polypeptide and the auxiliary antibacterial agent is 30%;

[0026] The preparation method comprises the following steps:

[0027] 1) Spray mixing: mix the antiviral active polypeptide, antiviral active agent, auxiliary antibacterial agent, taste masking agent and solvent in proportion to obtain a drug mixture, and add the drug mixture to a mixing container and mix at high speed;

[0028] 2) Atomization of the spray: add the drug mixture into the atomization device, which is preferably an air compression atomizer, a heating atomizer, a vibrating mesh microporous atomizer or an ultrasonic atomizer.

[0029] The antiviral active polypeptide is a viral prote...

Embodiment 3

[0031] refer to figure 1 , a method for making an active peptide bactericidal antiviral spray, comprising the following components in mass percentage: 25% antiviral active polypeptide, 20% antiviral active agent, 10% auxiliary antibacterial agent, 10% taste masking agent, and 35% solvent , the content of the antiviral active polypeptide and the auxiliary antibacterial agent is 30%;

[0032] The preparation method comprises the following steps:

[0033] 1) Spray mixing: mix the antiviral active polypeptide, antiviral active agent, auxiliary antibacterial agent, taste masking agent and solvent in proportion to obtain a drug mixture, and add the drug mixture to a mixing container and mix at high speed;

[0034] 2) Atomization of the spray: add the drug mixture into the atomization device, which is preferably an air compression atomizer, a heating atomizer, a vibrating mesh microporous atomizer or an ultrasonic atomizer.

[0035] The antiviral active polypeptide is a viral prote...

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Abstract

The invention discloses an active peptide sterilization antiviral spray. The active peptide sterilization antiviral spray comprises the following components of, in percentage by mass, 1%-30% of antiviral active polypeptide, 1%-30% of antiviral active agent, 1%-30% of auxiliary antibacterial agent, 1%-30% of taste masking agent and 1%-60% of solvent, wherein the contents of the antiviral active polypeptide and the auxiliary antibacterial agent are not 30% at the same time; the antiviral active polypeptide is a virus protease inhibition polypeptide, the mass percentage content of the antiviral active polypeptide is 1%-25%, preferably 5%-25%; the mass percentage content of the antiviral active agent is 1%-25%, preferably 5%-25%; the mass percentage content of the auxiliary antibacterial agentis 1%-25%, preferably 5%-25%; and the mass percent content of the taste masking agent is 1%-25%, preferably 5%-25%. The spray can inhibit replication of the novel coronavirus, inhibit inflammation and promote mucous membrane repair, so that the prevention and treatment effects of the novel coronavirus are achieved.

Description

technical field [0001] The invention relates to the technical field of antiviral sprays, in particular to a preparation method of an active peptide bactericidal antiviral spray. Background technique [0002] Active peptide is a general term for more than one thousand peptides (such as soybean peptide, deep-sea fish skin peptide, sea cucumber peptide, etc. are one of the active peptides). A peptide is a compound in which two or more amino acids are connected by peptide bonds. It plays an important physiological role in the human body and exerts physiological functions. Active peptides are called active peptides, also known as biologically active peptides or biologically active peptides. Active peptides play a key role in human growth and development, metabolism, disease, aging, and death. Active peptides are the most important active substances in the human body. It is precisely because of the increase or decrease of its secretion in the body that human beings have a cycle ...

Claims

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Application Information

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IPC IPC(8): A61K38/55A61K45/06A61K9/12A61K47/10A61P31/14A61P29/00A61K36/539A61K31/685A61K31/4706A61K31/427A61K31/513
CPCA61K38/55A61K36/539A61K45/06A61K31/685A61K31/4706A61K31/427A61K31/513A61K9/12A61K47/10A61P31/14A61P29/00A61K2300/00
Inventor 解放刘未斌
Owner 合肥天泰医疗科技有限公司