Application of semiliquidambar cathayensis or extract thereof in preparation of anti-depression drug

A technology for the extract of Scutellaria chinensis and its extract, which is applied in the field of application of scutellaria chinensis or its extract in the preparation of antidepressant drugs, achieving huge social and economic benefits, good industrialization prospects, and simple extraction methods

Active Publication Date: 2021-01-29
GUANGXI INST OF CHINESE MEDICINE & PHARMA SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Learned from document retrieval, in the prior art, only Banfenghe is disclosed as the medicine of anti-hepatitis B virus, promoting blood circulation and removing blood stasis, anti-inflammatory analgesia, osteoarthritis; It is used for the treatment of depression and related diseases caused by it, and the medicine for the treatment or suppression of depression does not contain the extract of maple leaf

Method used

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  • Application of semiliquidambar cathayensis or extract thereof in preparation of anti-depression drug
  • Application of semiliquidambar cathayensis or extract thereof in preparation of anti-depression drug
  • Application of semiliquidambar cathayensis or extract thereof in preparation of anti-depression drug

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Example 1 The preparation of the extract of the maple lotus

[0037]Take half maple lotus 1kg, add 6L distilled water to soak for 60min, then heat to 80°C to extract for 60min, filter, and collect the filtrate; Extract at ℃ for 60 minutes, filter, and collect the filtrate; combine the three extracts, concentrate to 1.0-1.2g / mL, and obtain the product.

Embodiment 2

[0038] Example 2 The preparation of the extract of maple lotus

[0039] Take half maple lotus 1kg, add 6L distilled water to soak for 60min, then heat to 90°C for extraction for 60min, filter, and collect the filtrate; Extract at ℃ for 60 minutes, filter, and collect the filtrate; combine the three extracts, concentrate to 1.0-1.2g / mL, and obtain the product.

Embodiment 3

[0040] Example 3 The preparation of the extract of maple lotus

[0041] Take half maple lotus 1kg, add 6L distilled water to soak for 60min, then heat to 98°C for extraction for 60min, filter, and collect the filtrate; Extract at ℃ for 60 minutes, filter, and collect the filtrate; combine the three extracts, concentrate to 1.0-1.2g / mL, and obtain the product.

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PUM

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Abstract

The invention discloses an application of semiliquidambar cathayensis or an extract thereof in preparation of an antidepressant drug, the semiliquidambar cathayensis is a dry root of Semiliquidambar cathayen.sis Chang, the extract of semiliquidambar cathayensis is an aqueous extract of semiliquidambar cathayensis or an organic solvent extract of semiliquidambar cathayensis. The extraction method of the extract is as follows: taking the semiliquidambar cathayensis, adding a solvent for soaking treatment, heating for extraction, combining liquid medicines extracted for multiple times and concentrating to obtain the extract. It is found for the first time that semiliquidambar cathayensis or the extract of semiliquidambar cathayensis has the obvious anti-depression activity and has the patentmedicine potential for preparing medicine preparations for preventing or treating depression and related diseases, the preparation method of the medicine preparations is simple, the cost is low, and the patent medicine economic benefits are good.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to the application of a kind of maple lotus or its extract in the preparation of antidepressant drugs. Background technique [0002] Depression is an affective disorder and mental illness characterized by low mood, lack of interest, and sleep disturbance. It has two high and one difficult treatment characteristics (high incidence, high recurrence rate, and difficult cure). The onset of depression does not choose race, people or gender. Due to the aggravation of many stress factors, depression has become a common disease with a high incidence in the current society. At present, there are 340 million depressed patients in the world, and the number of depressed patients in China has exceeded 26 million. In recent years, many celebrities, young students, and pregnant women have died of depression. Depression not only caused great mental torture to the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P25/24A61P19/02A61P29/00A61P21/00A61P15/00A23L33/105A61K125/00
CPCA61K36/185A61P25/24A61P19/02A61P29/00A61P21/00A61P15/00A23L33/105A61K2236/331A61K2236/39A61K2236/333A23V2002/00A23V2200/322A23V2200/30A23V2250/21Y02A50/30
Inventor 何俊慧韦洁李冬梅何飞韦桂宁韦冬梅李懿
Owner GUANGXI INST OF CHINESE MEDICINE & PHARMA SCI
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