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High-sensitivity liquid chromatography detection system

A liquid chromatography and detection system technology, applied in measurement devices, instruments, scientific instruments, etc., can solve the problems of narrow liquid passage, limited detection limit, limited optical path, etc., and achieve low detection limit, wide range and high compatibility. Effect

Pending Publication Date: 2021-02-09
上海倍蓝光电科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Usually the optical path is very short, 0.1mm or 1-2mm, the maximum is not more than 10mm. The disadvantage of this method is that the diameter of the liquid passage is usually relatively narrow or relatively short, and the optical path is limited, so the detection limit is limited. limited

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  • High-sensitivity liquid chromatography detection system
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Embodiment Construction

[0028] Exemplary embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings, these embodiments are for a more thorough understanding of the present invention and can fully convey the scope of the present disclosure to those skilled in the art. While the drawings show exemplary embodiments of the present disclosure, it is to be understood that the invention is not to be limited to the embodiments set forth herein.

[0029] A high-sensitivity liquid chromatography detection system, the detection optical path is changed from the transverse direction to the longitudinal direction, and the detection optical path is defined as a detection optical path unit that can change parameters such as length, thickness, etc. The optical path of light passing through the liquid path is changed from um to mm It can be extended to tens of mm or even hundreds of mm. It can be replaced according to the liquid concentration. The light inpu...

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Abstract

The invention discloses a high-sensitivity liquid chromatography detection system, which is characterized in that a liquid path joint group comprises an upper liquid path joint (1) and a lower liquidpath joint (2), and a coupling lens group comprises an upper coupling lens (6) and a lower coupling lens (7); liquid flows in from the upper liquid path joint (1) and flows out from the lower liquid path joint (2); liquid path and light path guide pipes (3) are mounted on the front side of the upper liquid path joint (1) and the rear side and the middle part of the lower liquid path joint (2); a light path coupling joint (4) is arranged at the top of the upper liquid path joint (1), a light source (5) is arranged at the top of the light path coupling joint (4), an upper coupling lens (6) is arranged at the joint of the light path coupling joint (4) and the upper liquid path joint (1), and a lower coupling lens (7) is arranged at the bottom of the lower liquid path joint (2). According to the invention, the optical path can be increased, the detection limit is improved, and the improved multiple can reach dozens of times or more.

Description

technical field [0001] The invention relates to biochemical analysis, more specifically a high-sensitivity liquid chromatography detection system for analyzing chemical components of substances and preparing, separating and purifying. Background technique [0002] The liquid chromatography detection system is an instrument that uses the difference in the distribution ratio of the mixture between liquid-solid or two immiscible liquids to separate the mixture first, and then analyze and identify it. Liquid chromatography is divided into liquid-liquid chromatography LLC and liquid-solid chromatography LSC according to whether the stationary phase is liquid or solid. A modern liquid chromatograph consists of a high-pressure infusion pump, a sampling system, a temperature control system, a chromatographic column, a detector, and a signal recording system. Compared with the classical liquid chromatography device, it has the characteristics of high efficiency, rapidity and sensiti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/02G01N30/74
CPCG01N30/02G01N30/74G01N2030/027
Inventor 于立民曹丽娜陈志伟
Owner 上海倍蓝光电科技有限公司