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Blood processing filter and method of manufacturing blood processing filter

A blood treatment and filter technology, applied in chemical instruments and methods, membrane filters, filtration and separation, etc., can solve problems such as maintaining the ability to remove white blood cells

Pending Publication Date: 2021-02-19
ASAHI KASEI MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, although this method can suppress the extension of the filtration time by reducing the pressure loss, it is difficult to maintain the leukocyte removal ability satisfactorily.

Method used

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  • Blood processing filter and method of manufacturing blood processing filter
  • Blood processing filter and method of manufacturing blood processing filter
  • Blood processing filter and method of manufacturing blood processing filter

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～16、 comparative example 1～7、9

[0135]Prepare the basis weight of the number of pieces shown in Table 1 and Table 2: 93 (g / m2), air resistance per unit basis weight: 0.03 (kPa·s·m / g), CWST: 95 (mN / m) polybutylene terephthalate (hereinafter referred to as "PBT") non-woven fabric Used as filter material A, basis weight: 90(g / m2), the air permeability resistance per unit basis weight: 0.06 (kPa·s·m / g), CWST: 96 (mN / m) PBT non-woven fabric as the filter material B, according to the upstream side, all of the filter material A , All the filter materials B are stacked in the order, and the filter materials are made in the form of a laminate.

[0136]The filter material is sandwiched between two flexible vinyl chloride resin sheets with holes that become the blood inlet or outlet, and the filter material and the peripheral part of the flexible sheet are welded and integrated using a high-frequency welding machine. The effective filter area is 43cm2After the blood processing filter was subjected to high pressure steam sterili...

Embodiment 17、18

[0138]As filter material A, use basis weight: 93 (g / m2), CWST: 95 (mN / m), air resistance per unit basis weight: 0.01 (kPa·s·m / g) or 0.04 (kPa·s·m / g) PBT non-woven fabric, in addition , The same operation as in Example 1.

Embodiment 19

[0140]As filter material B, use basis weight: 90(g / m2), CWST: 96 (mN / m), air permeation resistance per unit basis weight: 0.08 (kPa·s·m / g) PBT non-woven fabric, except that the operation was the same as in Example 1.

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PUM

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Abstract

The present invention provides a blood processing filter including: a container with two openings for the entry of a liquid to be processed and for the exit of a liquid that has been processed; and afiltering material filled in the container. The filtering material has a ventilation resistance of not less than 55.0 kPa.s / m and less than 85.0 kPa.s / m. The filtering material includes a filter material A of which ventilation resistance per unit area is not less than 0.01 kPa.s.m / g and less than 0.04 kPa.s.m / g, and a filter material B of which the ventilation resistance per unit area is not lessthan 0.04 kPa.s.m / g. At least a part of the filter material A is disposed on the side closer to the entry of the liquid to be processed than the filter material B. The total of the ventilation resistance of the filter material A disposed on the side closer to the entry of the liquid to be processed than the filter material B is not less than 6.0 kPa.s / m.

Description

Technical field[0001]The present invention relates to a blood processing filter and a method for manufacturing a blood processing filter for removing undesirable components such as aggregates and white blood cells from liquid or blood containing blood components.[0002]The present invention particularly relates to blood treatment filters suitable for blood treatment filters used for the purpose of removing micro-aggregates and white blood cells that cause side effects from whole blood preparations for blood transfusion, red blood cell preparations, platelet preparations, plasma preparations, etc. filter.Background technique[0003]When whole blood collected from a donor is used as a raw material for blood component preparations such as red blood cell preparations, platelet preparations, and plasma preparations, the whole blood contains various undesirable components such as micro aggregates and white blood cells that cause side effects of blood transfusion. Therefore, removal of undesi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/02B01D39/16
CPCA61M1/3635A61M1/0218A61M1/0281A61M2207/00B01D39/08B01D39/1623B01D2239/1291B01D39/1615B01D39/1692B01D39/1669B01D39/2017B01D2239/0421B01D2239/065A61M2202/0028A61M2202/0439A61M2205/75
Inventor 中村和彦横沟朋久甲斐多佳子
Owner ASAHI KASEI MEDICAL CO LTD