Composition for improving side effects of oral bowel cleansing or intestinal tract preparation agent electrolyte disorders

A technology of intestinal preparation and composition, applied in the field of medicine, which can solve the problems of patient health hazards, intestinal mucosal barrier damage, electrolyte loss, etc.

Active Publication Date: 2021-03-12
唐传生物科技(厦门)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, magnesium sulfate often causes rapid loss of electrolytes in the digestive juice during intestinal preparation, and at the same time reduces the effective absorption of supplemented electrolytes, resulting in electrolyte disturbances such as hyponatremia and hypokalemia, which are harmful to patients with intestinal preparation health hazard
And studies have also shown that intestinal cleansing agents such as magnesium sulfate often lead to increased intestinal m...

Method used

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  • Composition for improving side effects of oral bowel cleansing or intestinal tract preparation agent electrolyte disorders

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0123] This example 1 investigates the effect of L-arabinose and electrolytes on the improvement of electrolyte disturbance caused by intestinal preparation of magnesium sulfate

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PUM

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Abstract

The present invention relates to a composition for improving the side effects of oral gut purging or intestinal preparation agent electrolyte disorders. Specifically, the invention provides a composition which comprises arabinose, sodium sulfate, sodium chloride, potassium chloride and sodium bicarbonate. The invention finds that oral administration of arabinose, sodium sulfate, sodium chloride, potassium chloride and sodium bicarbonate can effectively improve the side effects of electrolyte disorder, intestinal mucosa permeability increase, intestinal mucosa injury, intestinal mucosa barrierdamage and the like caused in the intestinal tract preparation process of the bowel cleansing agent or the intestinal tract preparation agent; therefore, side effects caused by oral administration ofthe gut purge or the intestinal tract preparation are improved, and health recovery of intestinal tract preparation of a patient is improved.

Description

technical field [0001] The invention relates to the field of medicaments, in particular to a composition for improving the side effects of oral bowel cleansing or intestinal preparation preparation electrolyte disturbance. Background technique [0002] Electrolytes are widely distributed inside and outside cells, participate in various important metabolic activities in the body, and play a very important role in maintaining normal life activities. Disturbance of electrolyte metabolism can cause corresponding obstacles to the physiological functions of various organ systems, especially the cardiovascular system and nervous system, and the substance metabolism of the body. In severe cases, it can lead to animal death. Potassium ions in serum electrolytes can maintain the normal physiological activities of the body, ensure cell metabolism, especially the electrical activity of cardiomyocytes, normal functions of nerves and muscles, maintain normal acid-base balance, and stabili...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61K33/00A61K33/04A61K31/7004A61K33/06A61P3/12A61P1/00A23L33/16A23L33/125
CPCA61K33/14A61K33/00A61K33/04A61K31/7004A61K33/06A61P3/12A61P1/00A23L33/125A23L33/16A23V2002/00A61K2300/00A23V2250/602A23V2250/161A23V2250/1614A23V2250/16A23V2200/30A23V2200/32Y02A50/30
Inventor 林卫军石国良王羽娟蔡许斌郭志坚
Owner 唐传生物科技(厦门)有限公司
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