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Tibetan medicine compound for treating calf gastrointestinal diseases and preparation method thereof

A technology for gastrointestinal diseases and compound recipes, applied in the field of pharmaceutical preparations, can solve problems such as inability to achieve therapeutic effects, and achieve the effects of not easy bacterial drug resistance, high-efficiency therapeutic effects, and inhibition of intestinal epithelial cell shedding

Active Publication Date: 2021-04-09
LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For complex calf diarrhea, the therapeutic effect is still not achieved

Method used

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  • Tibetan medicine compound for treating calf gastrointestinal diseases and preparation method thereof
  • Tibetan medicine compound for treating calf gastrointestinal diseases and preparation method thereof
  • Tibetan medicine compound for treating calf gastrointestinal diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-5

[0041] The preparation of the Tibetan medicine compound oral liquid for the treatment of calf diarrhea type colitis provided by the invention:

[0042]The composition of the Tibetan medicine compound oral liquid is shown in the table, and the data in Table 1 are mass percentages.

[0043] Table 1 Tibetan medicine compound prescriptions with different ratios

[0044]

[0045]

[0046] Preparation:

[0047] (1) Take three needles, fennel grass, Gentiana officinalis, Myrobalan chebula, Ganqing Qinglan, and Corydalis dwarf according to the proportion, and wash with cold water to remove floating dust;

[0048] (2) Add medicinal materials in step (1), soak in cold water for 24 hours;

[0049] (3) In the airtight decoction machine, add the medicinal materials soaked in step (2), add 5-10 times the volume of water, and decoct in water for 2 hours at 115°C;

[0050] (4) four layers of gauze filter and collect step (3) decocted medicinal liquid;

[0051] (5) Add 5-10 times mor...

Embodiment 6

[0059] Example 6: Study on antidiarrheal, analgesic and antibacterial effects of Tibetan medicine compound

[0060] 1. Antibacterial effect research

[0061] The antibacterial test of Tibetan medicine compound oral liquid on highly drug-resistant Escherichia coli isolates in calves with diarrhea was carried out by the Oxford cup method. According to the proportions of Examples 1, 2, 3, 4, and 5, the medicines are taken, wherein, the medicines taken in Example 1 are: 200 grams of three needles, 300 grams of Cyperus chinensis, 200 grams of Gentiana chinensis, 200 grams of Myrobalan, and Ganqing Qinglan 100 grams, 100 grams of Corydalis dwarf, and the medicines taken in Example 2 are: 300 grams of three needles, 300 grams of Cedarwort, 300 grams of Gentiana chinensis, 200 grams of Myrobalan, 100 grams of Ganqing Qinglan, 100 grams of Corydalis dwarf, implement The medicines taken in Example 3 are: 100 grams of three needles, 100 grams of Lemongrass, 100 grams of Gentiana officin...

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Abstract

The invention relates to a Tibetan medicine compound for treating calf gastrointestinal diseases and a preparation method thereof, and relates to the technical field of pharmaceutical preparations. The Tibetan medicine compound is prepared from the following raw materials in parts by weight: 1 to 3 parts of berberis julianae schneid, 1 to 3 parts of herba elsholtziae, 1 to 5 parts of radix gentianae macrophyllae, 2 parts of fructus chebulae, 1 part of herba dracocephali tangutici and 1 part of herba corydalis. The Tibetan medicine compound provided by the invention has the effects of inhibiting bacteria, stopping diarrhea and easing pain, and also has the effect of reducing the intestinal propulsion rate; the intestinal epithelial cell falling is inhibited; the mucosal edema is reduced; the inflammatory cell infiltration is reduced; the fast healing of diarrhea is promoted; the bacterial drug resistance cannot be easily generated; and the animal production performance is not influenced.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a compound Tibetan medicine prescription for treating calf gastrointestinal diseases and a preparation method thereof. Background technique [0002] Gastrointestinal diseases cover diseases of the esophagus, stomach, small intestine, colon and rectum. The common main symptoms include rhythmic and periodic epigastric pain, diarrhea, hunger abdominal pain, acid reflux, fever, black and bloody stools, gastrointestinal bleeding and intestinal obstruction etc. Gastrointestinal disorders are among the most common in humans, the most common of which include dysphagia, gastric ulcer, peptic ulcer, gastroparesis, delayed gastric emptying, irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Calf diarrhea seriously affects the healthy development of cattle breeding industry. Calf diarrhea is caused by pathogenic microorganisms such as bacteria, viruse...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/66A61K9/08A61P1/00A61P29/00A61P1/12
CPCA61K36/29A61K36/53A61K36/534A61K36/515A61K36/185A61K36/66A61K9/0095A61K47/12A61P1/00A61P29/00A61P1/12A61K2236/13A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2300/00Y02A50/30
Inventor 张凯李建喜张康仇正英王磊张景艳王贵波郭志廷王学智
Owner LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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