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Traditional Chinese medicine composition for treating depression and preparation and application thereof

A composition and technology for depression, applied in the field of medicine, can solve problems such as application limitation, cancer of reproductive system, etc.

Active Publication Date: 2021-04-23
WUXI HEALTH VOCATIONAL & TECHN SCHOOL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The onset of PMD is closely related to the decline of estrogen level. Estrogen replacement therapy (Estrogen Replacement Therapy, ERT) can improve the symptoms of PMD, but the estrogen treatment of depression is limited by the window period, and there is a risk of inducing reproductive system cancer. The application is also restricted. limit

Method used

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  • Traditional Chinese medicine composition for treating depression and preparation and application thereof
  • Traditional Chinese medicine composition for treating depression and preparation and application thereof
  • Traditional Chinese medicine composition for treating depression and preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] (1) Grinding: Take 6 parts of Angelica sinensis, 4 parts of Bamboo leaves, 3 parts of Jujube Seed, 2 parts of Radix Astragali, 3 parts of Licorice Root, 1 part of Radix Paeoniae Alba, and grind them separately. The medicinal material powder to be extracted;

[0033] (2) Extraction: Add water to decoct the medicinal material powder obtained in step (1) twice, add 10 times the weight of the medicinal material powder for the first time and decoct for 2 hours, and add water 8 times the weight of the medicinal material powder to be extracted for the second time Decoct for 2 hours and combine the water decoction; for the third time, add 10 times the amount of ethanol of the medicinal material powder to be extracted for reflux extraction for 2 hours, for the fourth time add 8 times the amount of ethanol for extraction of the medicinal material powder for 2 hours, and combine the ethanol extract .

[0034] (3) Concentration: Cool the water decoction obtained in step (2) and le...

Embodiment 2

[0037] (1) Grinding: Take 6 parts of Angelica sinensis, 4 parts of Danzhu leaves, 3 parts of Jujube Seed, 2 parts of Radix Astragali, 3 parts of Radix Glycyrrhizae, 1 part of Radix Paeoniae Alba, and grind them separately. The medicinal material powder to be extracted;

[0038] (2) Extraction: Add water to the medicinal material powder to be extracted obtained in step (1) and decoct twice, add 10 times the weight of the medicinal material powder for the first time and decoct for 1 hour, and add water 8 times the weight of the medicinal material powder to be extracted for the second time Decoct for 1 hour and combine the water decoction; for the third time, add 10 times the amount of ethanol of the medicinal material powder to be extracted for reflux extraction for 1 hour, for the fourth time add 8 times the amount of ethanol for extraction of the medicinal material powder for 1 hour, and combine the ethanol extract .

[0039] (3) Concentration: Cool the water decoction obtain...

Embodiment 3

[0042] (1) Pulverization: Take 6 parts of Angelica sinensis, 4 parts of Bamboo leaves, 3 parts of Jujube Seed, 2 parts of Radix Astragali, 3 parts of Licorice Root, 1 part of Radix Paeoniae Alba, and grind them separately. The medicinal material powder to be extracted;

[0043] (2) Extraction: Add water to decoct the medicinal material powder obtained in step (1) twice, add 10 times the weight of the medicinal material powder for the first time and decoct for 6 hours, and add water 8 times the weight of the medicinal material powder to be extracted for the second time Decoct for 6 hours and combine the water decoction; for the third time, add 10 times the amount of ethanol of the medicinal material powder to be extracted for reflux extraction for 3 hours, for the fourth time add 8 times the amount of ethanol for extraction of the medicinal material powder for 3 hours, and combine the ethanol extract .

[0044] (3) Concentration: Cool the water decoction obtained in step (2) a...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating depression. The traditional Chinese medicine composition comprises the following components in parts by weight: 6 parts of angelica sinensis, 4 parts of lophatherum gracile, 3 parts of spina date seeds, 2 parts of astragalus membranaceus, 3 parts of liquorice and 1 part of radix paeoniae alba. The angelica sinensis is commonly used for treating dizziness and palpitation, the lophatherum gracile is used for treating delirium and annoyance, apoplexy aphonia, painful headache, and relieving palpitation and coma, and the spina date seeds have the effects of nourishing heart and tonifying liver, calming heart and tranquilizing, arresting sweating and promoting salivation and are commonly used for treating insomnia with weakness and irritability and palpitation and dreaminess. Radix bupleuri has the effects of reconciling superficies and interior, soothing the liver and raising yang, and is commonly used for treating liver Qi stagnation, sternal rib swelling pain and the like, the astragalus membranaceus has the effects of tonifying qi and strengthening superficies, stopping sweating and treating sex hormone, and the radix paeoniae alba has the effects of warming yang and clearing damp, tonifying body deficiency, strengthening the spleen and stomach and the like. The traditional Chinese medicine composition disclosed by the invention accords with the compatibility principle of all medicines, and a preparation of the traditional Chinese medicine composition can be used for treating depression. A formula is reasonable in compatibility and remarkable in effect; the cost is low, and side effects are small; and the clinical effect is obvious.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating depression, its preparation and application, and belongs to the technical field of medicine. Background technique [0002] Depression refers to the disorder of human brain structure and function under the action of biological, psychological and social factors, resulting in varying degrees of disorders in cognition, emotion, will and other mental activities. According to the WHO Global Burden of Disease study, depressive disorders account for 10% of the disability caused by non-infectious diseases, and it is estimated that by 2020 it will become the second largest source of disease burden after cardiovascular diseases. Many patients with major depressive disorder committed suicide because they did not receive formal treatment in time. Suicide is the fifth cause of death among Chinese population, and the first cause of death among people aged 15-34. Therefore, it is of gre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P25/24
CPCA61K36/232A61K36/899A61K36/725A61K36/481A61K36/484A61K36/71A61K36/65A61P25/24A61K2236/331A61K2236/39A61K2236/33A61K2236/55A61K2300/00
Inventor 徐红丹彭玉勃张正一雷霞刘国良孙琪祁永华
Owner WUXI HEALTH VOCATIONAL & TECHN SCHOOL