Pancreatic cancer detection panel based on next-generation sequencing technology, kit and application thereof

A second-generation sequencing technology and detection kit technology, which is applied in the direction of recombinant DNA technology, microbial measurement/inspection, specific-purpose bioreactor/fermenter, etc., can solve the problem of low coverage, high cost, and no cancer issues such as guidance
CN112852966APending Publication Date: 2021-05-28FUDAN UNIV SHANGHAI CANCER CENT
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Patent Information

Authority / Receiving Office
CN Β· China
Current Assignee / Owner
FUDAN UNIV SHANGHAI CANCER CENT
Publication Date
2021-05-28

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Abstract

The invention belongs to the technical field of pancreatic cancer multi-gene detection, and discloses a pancreatic cancer detection panel based on a next-generation sequencing technology, events such as gene mutation, copy number variation and the like having clear clinical correlation with pancreatic cancer, a multi-gene screening list is made into a probe, high-risk genes are detected in a targeted manner through DNA sequencing, gene mutation with guiding significance on diagnosis and treatment can be detected more efficiently, mutant genes can be detected in a targeted mode, and the gene detection cost of patients can also be reduced.
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Description

technical field

[0001] The invention belongs to the technical field of multi-gene detection of pancreatic cancer, and relates to a pancreatic cancer detection panel, a kit and applications thereof based on next-generation sequencing technology. Background technique

[0002] Pancreatic cancer is a highly malignant tumor of the digestive tract that is difficult to diagnose and treat. About 90% of them are ductal adenocarcinomas originating from the ductal epithelium. The morbidity and mortality have increased significantly in recent years. The 5-year survival rate is <1%, and it is one of the malignant tumors with the worst prognosis. The early diagnosis rate of pancreatic cancer is not high, the surgical mortality rate is high, and the cure rate is very low.

[0003] The application of gene sequencing to determine the targeted treatment plan for patients has become more and more common in pancreatic cancer. However, the existing sequencing of pancreatic cancer either focu...

Claims

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