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Device and method for diagnostic testing of COVID-19, viruses, antibodies and markers

A biodetector, bioassay technology, applied in biochemical equipment and methods, chemical instruments and methods, and microbial determination/inspection, etc., can solve the problems of analysis delay, low sensitivity, etc.

Pending Publication Date: 2021-06-18
自主医疗设备公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[40] One of the challenges is to find targets specific to SARS-CoV-2
Abbott responded that this issue may be caused by analysis delays
Another study rejected the test in their clinical setting because of this low sensitivity

Method used

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  • Device and method for diagnostic testing of COVID-19, viruses, antibodies and markers
  • Device and method for diagnostic testing of COVID-19, viruses, antibodies and markers
  • Device and method for diagnostic testing of COVID-19, viruses, antibodies and markers

Examples

Experimental program
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Embodiment Construction

[0106] The device of the illustrated embodiment includes a central unit that includes electronic components, cameras, optical components, digital data collection components, and communication components to communicate with a cloud-based expert diagnostic server via the Internet, and to provide information on Covid-19 and other viruses or Electromechanical components required for on-site portable diagnostic testing of bacterial infections. The same hub unit supports at least three different microfluidic discs 68 (CD) for diagnostic assays or detection, i.e., microarrays for antibodies such as IgG and IgM for virological detection using surface acoustic wave (SAW) detectors Serological detectors, as well as RT-PCR assays for nucleic acid targets using fluorescent detectors, are designated by Autonomous Medical Devices Inc. as detectors A10, A20, and A30 CD, respectively. The unit and its corresponding CD are measuring or assaying devices that do not perform high-level diagnostic...

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Abstract

An automated system that communicates with a remote server and is used to perform diagnostic field tests on samples collected from patients using automated portable handheld instruments to determine the presence of Covid-19 and / or antibodies. The system includes: a microfluidic circuit defined in a rotatable disk, which is used to perform a bioassay using a microarray to generate an electrical signal indicating a measurement value of the bioassay; a microarray operably located in a microfluidic circuit; one or more lasers; one or more positionable valves in the microfluidic circuit; a central unit, which is used to rotate the disk for biometrics according to the protocol, is used to control the laser to selectively open the positionable valve in the microfluidic disk, and is used to operate the microarray to generate a digital image as a biometric measurement and used to transmit biometric measurement values to a remote server, and used to associate the performed biometric measurement and its corresponding biometric measurement value with the patient.

Description

[0001] This application is a continuation-in-part and claims priority and benefit of an earlier filed U.S. non-provisional patent application entitled "An Automated, Cloud-Based, Point-of-Care (POC) Pathogen and Antibody Array Detection Systems and Methods," filed June 25, 2020, Serial No. 16 / 912,568, pursuant to 35 USC 120, the entire contents of which are incorporated herein by reference. technical field [0002] The present invention relates to the field of point-of-care (POC) pathogen and multiplex pathogen and antibody array detection platforms and methods, as in CPC C40B 60 / 12. Background technique [0003] COVID-19 testing involves analyzing samples to assess for the current or past presence of SARS-CoV-2. These two main branches detect the presence of viruses or the presence of antibodies produced as a result of infection. Virus presence tests are used to diagnose individual cases and allow public health authorities to track and contain outbreaks. Instead, antibody...

Claims

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Application Information

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IPC IPC(8): G16H10/40G01N33/569G01N33/68
CPCG16H10/40G01N33/56983G01N33/6854G01N2333/165G16H50/80G01N33/54366B01L3/50273B01L2200/0605B01L2300/0636B01L2300/0803B01L2400/0409B01L2300/023B01L2300/021Y02A90/10B01L3/5027C12Q1/6804C12Q1/70G01N29/02G01N33/48G01N33/483G01N33/569G01N35/00G01N35/00871G01N35/00069G16H40/67G16H50/20G16H50/50B01L3/502715G01N2035/00881G01N2035/00158B01L2300/026B01L2300/0663
Inventor J·沙查尔R·科恩伯格
Owner 自主医疗设备公司
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