37 results about "Diagnostic Test Result" patented technology

This invention belongs to the field of diagnostic testing technology. Addressing the problem that existing gestational diabetes screening methods may miss the optimal time for early intervention, leading to the failure to promptly detect and manage some potentially hyperglycemic pregnant women, increasing the risk of adverse maternal and fetal outcomes, this invention proposes a plasma metabolic biomarker for the early diagnosis or prediction of gestational diabetes and its application. This plasma metabolic biomarker is at least one of L-lysine, propargylglycine, N6-acetyl-L-lysine, cyclic leucine, and glycine-deoxycholic acid. The five plasma metabolic biomarkers provided by this invention can be applied to the early diagnosis or prediction of gestational diabetes, and are of great significance for the prevention or treatment of gestational diabetes.

The present disclosure relates to techniques for preprocessing samples and using preprocessed samples and machine learning models to predict clinical diagnostic tests for a patient from their historical laboratory testing data. Particularly, aspects are directed to obtaining datasets including features and / or historical laboratory test results for subjects, filtering the datasets based on a denoise-balance scheme to obtain filtered datasets, training a machine learning model using the filtered datasets to obtain a trained machine learning model, and providing the trained machine learning model. A candidate machine learning model may be an ensemble of classifiers implemented with a boosting algorithm, and the ensemble is trained by applying base machine learning algorithms on different distributions of the filtered datasets. The ensemble is then combined into a machine learning model having the set of learned model parameters for predicting results for clinical diagnostic tests.

EMBEDDED ML VLSI DATA PROCESSING DEVICE FOR REAL-TIME PROCESSING AND DIAGNOSTIC TESTING

In some embodiments, a method of operating a plurality of diagnostic engines is provided. The method of operating includes receiving, via an instrument data manager (IDM) in communication with a plurality of diagnostic engines, a selection of one of the plurality of diagnostic engines for testing a sample of a patient; employing the IDM to disable at least one of the plurality of diagnostic engines that was not selected; prior to displaying a test result from the selected diagnostic engine for the sample of the patient, requiring entry of at least one of patient information and sample information; and after receiving entry of the patient information or sample information, employing the IDM to enable any disabled diagnostic engine. Numerous other embodiments are provided.

Managing diagnostic testing of computing hardware, including: identifying a particular computing hardware for performing a diagnostic test at, the particular computing hardware associated with a shared library; receiving telemetry data associated with the particular computing hardware; determining that the telemetry data indicates a possible security event associated with the particular computing hardware, and in response: providing data indicating the shared library to a third-party vulnerability scanning service; receiving, from the third-party vulnerability scanning service, data indicating a security vulnerability of the shared library, and in response: identifying a diagnostic test that is implemented at the particular computing hardware via side band communication channel of the particular computing hardware; implementing, through the side band communication channel, the diagnostic test at the particular computing hardware; determining that the diagnostic test failed at the particular computing device, and in response, performing, independent of user action, a corrective action at the particular computing hardware.

This application relates to the field of diagnostic testing of electronic control units (ECUs), and discloses a diagnostic testing method and apparatus for ECUs. The method includes: obtaining a structured diagnostic process configuration file, the configuration file defining a sequence of diagnostic steps including at least one user data injection point and data filling rules corresponding to the injection point; in response to executing the diagnostic step sequence to reach the user data injection point, obtaining external data input by the user; and dynamically filling the external data into a specified position of the diagnostic message to be sent according to the data filling rules. This application solves the problem of rigid automated diagnostic testing processes that cannot be compatible with dynamic data input at runtime, and achieves a flexible unification of automated testing processes and user dynamic input requirements. It maintains the consistency of automated execution while improving the reusability and adaptability of testing tools to different testing scenarios.

The present invention is directed to olfactory diagnostic testing compositions and kits for detecting, screening and / or monitoring the progression of specific disease states or other conditions in a subject. In one aspect, the invention is directed to a method and testing kit using a pathology-specific panel of fragrances to detect, screen and / or monitor a specific disease state or condition. In another aspect, the invention is directed to a method of making diagnostic compositions having a specific complex fragrance such as an essential oil fragrance and diagnostic testing kits including such diagnostic compositions.

To provide a method and device for analyzing non-volatile organic substances in exhaled breath. [Solution] A method and device for analyzing non-volatile organic compounds in exhaled breath and other aerosols is disclosed, using a variety of diagnostic tools that enable rapid, low-cost point-of-care assays for several diseases, including respiratory diseases such as COVID-19. The disclosed method and system selectively captures non-volatile organic compounds in exhaled breath and other aerosols in a packed bed column. The non-volatile organic compounds are eluted, and the sample is analyzed using a diagnostic instrument, including MALDI-TOFMS. The disclosed system and method provide diagnostic test results in less than approximately 20 minutes and enable autonomous operation with minimal human intervention.

A method for estimating a number of phagocytes in a body fluid of an animal includes stimulating NADPH oxidase activity of the phagocytes; and quantifying a resulting reductive dioxygenation of a chemiluminigenic substrate by an emitted chemiluminescence of the chemiluminigenic substrate using an instrument capable of measuring light. The NADPH oxidase activity of the phagocytes is preferably stimulated by an immunologic or chemical capable of activating a respiratory burst by the phagocytes. The NADPH oxidase activity of the phagocytes is preferably stimulated by a stimulus in solution or coated to a surface contacted by the phagocytes. The stimulus is preferably phorbol myristate acetate (PMA). The animal is preferably human, and the body fluid is preferably blood and / or spinal fluid. The phagocytes are preferably neutrophil leukocytes, and the chemiluminigenic substrate is preferably lucigenin (N,N′-dimethyl-9,9′-biacridinium dinitrate). Also provided is a method of treatment based on the estimation method.

Methods and apparatus for automatically determining a diagnostic test result from a lateral flow assay are provided. The method comprises receiving at least one image of the lateral flow assay, identifying, with a hardware computer processor, a view window in the at least one image, determining, within the identified view window, a first signal strength for a control line and a second signal strength for one or more test lines, determining the diagnostic test result based on the first signal strength and / or the second signal strength, and outputting an indication of the diagnostic test result.

The present disclosure relates to a storage device for an automated diagnostic testing system and an automated diagnostic testing system including the same. More particularly, the storage device includes a storage area configured to store materials, an identification information reader, a material dispensing interface configured to interact with a transfer device of the automated diagnostic testing system, and a controller configured to control the storage device, wherein the controller determines, based on identification information of a sample loaded in the automated diagnostic testing system, materials to be supplied to a functional device, and controls the storage device such that the determined materials are supplied to the functional device.

Systems and methods for integration of user-administered diagnostic test results with electronic health records are provided. In one aspect, a method includes receiving a prescription specifying a user-administered test and a patient, transmitting prescription information to a pharmacy and to the test provider, generating a unique order identifier which is sent to a user application that associates the order identifier with a test result after the user administers the test, receiving the test result in association with the order identifier, storing the test result and the order identifier in a medical record database in association with a medical record number or a consultation identifier, and sending a notification of the test result to the prescribing clinician.

The invention relates to application of a myocardial injury marker RSPO1 in preparation of a product for identifying cardiovascular diseases. The invention evaluates the expression profiles of all LGR4 ligands under cardiovascular diseases at present, provides the application of RSPO1 as a potential drug target, and further provides the application of the myocardial injury marker RSPO1 in preparation of products for identifying cardiovascular diseases based on the application. The invention also provides application of the reagent for detecting the RSPO1 protein level in preparation of products for diagnosing cardiovascular diseases. According to the invention, the problem of insufficient adaptability and specificity of the existing marker is solved, RSPO1 is developed into a diagnostic marker, a DY4645-05 ELISA kit is adopted for detection and adaptation of multiple samples such as serum, multiple cardiovascular diseases can be diagnosed, cross-species application is realized, a basic research and clinical diagnosis detection system is unified, and powerful support is provided for diagnosis and treatment of cardiovascular diseases.

This invention relates to the field of automotive technology and discloses a vehicle diagnostic method, device, and storage medium for vehicles with separate upper and lower body panels. The vehicle diagnostic method determines whether the suppliers of the upper and lower body panels are the same to provide corresponding diagnostic methods. If the suppliers of the upper and lower body panels are the same, the diagnosis of both upper and lower body panels is achieved through a first gateway; if the suppliers of the upper and lower body panels are different, the diagnosis of both upper and lower body panels is achieved through both the first gateway and a second gateway. This invention fulfills the diagnostic requirements for vehicles with separate upper and lower body panels; simultaneously, it provides a complete diagnostic system for emerging electric vehicle manufacturers without experience in whole-vehicle development, covering diagnostic implementation at the vehicle end, and diagnostic testing needs from engineering to after-sales service.

1. Name of the product in this design: Calibration and calibration plate (ADAS). 2. Purpose of this design: To be attached to the surface of vehicle glass to assist advanced driver assistance systems in diagnostic testing and calibration. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The disclosed diagnostic test cartridges collect a controlled amount of a patient sample using a capillary slide. The capillary slide mates with a capillary channel to cause diluent to mix in a controlled manner with the patient sample to prepare it for further processing, such as sonication and diagnostic testing. The cartridge can be a two-part design in some examples that selectively couple together to cause the patient sample to be collected in a controlled manner and the diluent to be released to mix with the patient sample in a controlled manner to improve the quality of the prepared sample for diagnostic testing.

The invention relates to a method for detecting and signaling security events occurring in an automation component (100) within an automation system, and to an automation component suitably configured, in particular for carrying out the method. It is specifically proposed that, in response to the initiation of an activation process, i.e., the switching on and startup of the automation component, the firmware stored in it is executed by a processor (110), and that during the activation process of the automation component, a security manager (120) checks the firmware to be executed by the processor before it is processed.is subjected to a diagnostic test; and a security event based on the result of the diagnostic test is displayed by a security indicator instrument (160) that interacts with the security manager and / or the processor solely for the purpose of displaying such security events based on the result of the diagnostic test.

Providing enriched antigen-specific antibodies for analytical and therapeutic use. [Solution] The present invention relates to a method for eliminating interference as described herein, or for enriching or isolating biomarkers, particularly antibodies, before diagnostic testing, or for use for prophylactic or therapeutic purposes, using particles (e.g., fine particles, nanoparticles; magnetic, nonmagnetic) having a surface containing the capture portion described herein. A simple, efficient, and cost-effective method for conditioning biological samples to control and mitigate a number of known sample-specific interferences that can result in erroneous test results and increased risks to patient safety, such as heterophilic antibodies in patients treated with monoclonal mouse antibodies or patients who have received them for diagnostic purposes, is described herein.

Embodiments of the method for diagnostic testing include: providing a sampling kit to a subject, the sampling kit including a sample container for receiving a sample from a collection site of the subject; receiving the sample from the subject; generating a microbiome sequence dataset based on sequencing nucleic acid content of a microbial portion of the sample; detecting a presence of a set of microbiome targets; generating a diagnostic analysis based on the detected set of microbiome targets; generating a therapy recommendation based on the set of microbiome targets; and scheduling the therapy recommendation in coordination with a presentation of information derived from the diagnostic analysis.

Disclosed are mutations in the MEN1 gene of cancer cells that affect sensitivity of the cells to menin-inhibitory therapeutics. Also disclosed are diagnostic tests to detect the mutations. Diagnostic testing of cancer cells from a patient undergoing therapy with menin inhibitors can indicate that the therapy should be changed or stopped. Diagnostic of cells from a patient prior to treatment with a menin inhibitors can indicate an alternative therapy should be used.

A system and method, the method comprising receiving a laboratory diagnostic testing result associated with a specimen of a subject, the steps of receiving a clinomic profile of the subject, identifying a cohort of similar subjects based at least in part on the clinomic profile of the subject, providing the diagnostic testing results, clinomic profile, and the cohort of similar subjects to a smart output module to generate a personalized, precision medicine based laboratory diagnostic testing result as a smart output and displaying the smart output to a user.

Briefly, one or more embodiments are direct to a process, system, and article for transmitting a request for a diagnostic scan of a vehicle from a diagnostic application running on a computing device to an On-Board Diagnostic (OBD) system of a vehicle. A file may be received, by the diagnostic application, from the OBD system of the vehicle in response to the OBD system performing the diagnostic scan. The diagnostic application may launch a web browser application to display results stored in the file. A web browser extension of the web browser application may copy the file to generate a file copy. The file copy may be transmitted by the web browser extension to a diagnostic test results database.

Neurostimulation assemblies, systems, and methods make possible the providing of short-term therapy or diagnostic testing by providing electrical connections between muscles and / or nerves inside the body and stimulus generators and / or recording instruments mounted on the surface of the skin or carried outside the body. The assembly affords maximum patient mobility and comfort through differentiated components having minimal profiles and connected by way of detachable and adjustable connections.

The disclosed systems and method create an optically-readable code, such as a QR code, based on diagnostic test results and output for display or storing in memory the optically-readable code along with input patient data. The patient data can include patient biographic data, patient history, and medical records, for example. The optically-readable code can include the present diagnostic test results along with any past test results for the patient. The patient results include both input data about the patient and generated data about the diagnostic test results. This information is encoded in an optically-readable code, which can be displayed and stored in environments that do not have developed infrastructure to communicate with remote servers and devices, such as in remote location or under-served communities that do not have reliable Wi-Fi.

A method for estimating a number of phagocytes in a body fluid of an animal includes stimulating NADPH oxidase activity of the phagocytes; and quantifying a resulting reductive dioxygenation of a chemiluminigenic substrate by an emitted chemiluminescence of the chemiluminigenic substrate using an instrument capable of measuring light. The NADPH oxidase activity of the phagocytes is preferably stimulated by an immunologic or chemical capable of activating a respiratory burst by the phagocytes. The NADPH oxidase activity of the phagocytes is preferably stimulated by a stimulus in solution or coated to a surface contacted by the phagocytes. The stimulus is preferably phorbol myristate acetate (PMA). The animal is preferably human, and the body fluid is preferably blood and / or spinal fluid. The phagocytes are preferably neutrophil leukocytes, and the chemiluminigenic substrate is preferably lucigenin (N,N′-dimethyl-9,9′-biacridinium dinitrate). Also provided is a method of treatment based on the estimation method.

The invention concerns a combined magnetic resonance imaging and positron emission tomography apparatus (1) comprising: a magnetic resonance imaging machine (2), adapted to provide a total-body anatomical image of a patient undergoing diagnostic testing; a positron emission tomography machine (3), adapted to provide a total-body metabolic image of said patient undergoing diagnostic testing; at least one sliding table (4), adapted to accommodate the patient undergoing diagnostic testing by means of said machines (2, 3); a control console (5), operatively associated with said machines (2, 3) and with said sliding table (4), wherein the machines (2, 3) are configured to cooperate reciprocally to generate total-body diagnostic images obtained with the acquisition, reconstruction and analysis of PET metabolic images integrated with MRI attenuation maps, thus allowing total-body MRI-PET diagnostic images to be obtained deriving from the superimposition of metabolic and anatomical images of the patient under examination.

This application discloses a method, apparatus, and related equipment for processing Open Diagnostic Data Exchange (ODX) files, relating to the field of automotive technology. The method includes: acquiring an Open Diagnostic Data Exchange (ODX) file set for a vehicle, and acquiring a target ODX file. The ODX file set includes at least one ODX file, each ODX file describing the diagnostic specifications of a corresponding Electronic Control Unit (ECU), and each ODX file including diagnostic service information and diagnostic data structure information for the corresponding ECU; acquiring diagnostic data from each ODX file based on the ODX file set, and acquiring the diagnostic service information, diagnostic data structure information, and diagnostic service inheritance relationship information for each ECU; integrating the diagnostic service information and diagnostic data structure information of each ECU into the target ODX file according to the diagnostic service inheritance relationship information to obtain an integrated target ODX file, which is used for diagnostic testing.

An electric tool device and a method are disclosed, wherein the electric tool device comprises a device housing, an electric tool battery interface coupled to the device housing, and an electronic control unit. The electronic control unit comprises memory for storing firmware and a processor configured to execute the firmware to cause the electronic control unit to: receive a request from an external device to perform a self-test; perform the self-test in response to the request; record results according to the self-test; and export the results to the external device. The electric tool device may also include an integrated diagnostic circuit comprising a separate processing circuit, a diagnostic sensor, and an external communication interface.The integrated diagnostic circuit receives power from an external device, performs a diagnostic test of the electronic control unit, and sends a test result of the electronic control unit's diagnostic test to the external device.